LP68399-2
Galectin 3
Active
Descriptions
Galectin-3 is a member of the lectin family, of which 14 mammalian galectins have been identified. Galectin-3 is approximately 30 kDa and, like all galectins, contains a carbohydrate-recognition-binding domain (CRD) of about 130 amino acids that enable the specific binding of β-galactosides. Galectin-3 is encoded by a single gene, LGALS3, located on chromosome 14, locus q21-q22. It is expressed in the nucleus, cytoplasm, mitochondrion, cell surface, and extracellular space. This protein has been shown to be involved in the following biological processes: cell adhesion, cell activation and chemoattraction, cell growth and differentiation, cell cycle, and apoptosis. Given galectin-3's broad biological functionality, it has been demonstrated to be involved in cancer, inflammation and fibrosis, heart disease, and stroke. Studies have also shown that the expression of galectin-3 is implicated in a variety of processes associated with heart failure, including myofibroblast proliferation, fibrogenesis, tissue repair, inflammation, and Ventricular remodeling. Elevated levels of galectin-3 have been found to be significantly associated with higher risk of death in both acute decompensated heart failure and chronic heart failure populations Copyright Text is available under the Creative Commons Attribution/Share-Alike License. See http://creativecommons.org/licenses/by-sa/3.0/ for details. Source: Wikipedia , Wikipedia
Galectin-3 is a member of the protein family known as galectins. Galectins bind to certain carbohydrates via specific carbohydrate recognition domains (CRDs)
Blood levels of galectin-3 may be increased in patients with certain forms of advanced cancer and other conditions with organ fibrosis.
Source: LOINC partner 1
Basic Part Properties
- Part Name
- Galectin 3
- Part Display Name
- Galectin 3
- Part Type
- Component (Describes the core component or analyte measured)
- Created On
- 2008-04-07
- Construct for LOINC Short Name
- Galectin 3
LOINC Terminology Service (API) using HL7® FHIR® Get Info
Requests to this service require a free LOINC username and password. Below is a sample of the possible capabilities. See the LOINC Terminology Service documentation for more information.
- CodeSystem lookup
- https:
//fhir.loinc.org/CodeSystem/$lookup?system=http: //loinc.org&code=LP68399-2
Language Variants Get Info
| Tag | Language | Translation |
|---|---|---|
| es-ES | Spanish (Spain) | Galectina 3 |
| it-IT | Italian (Italy) | Galectina 3 |
| et-EE | Estonian (Estonia) | Galektiin 3 |
| tr-TR | Turkish (Turkey) | Galektin 3 |
| ru-RU | Russian (Russian Federation) | Галектин 3 |
| fr-BE | French (Belgium) | Galectine 3 |
| nl-NL | Dutch (Netherlands) | galectine 3 |
| zh-CN | Chinese (China) | 半乳糖凝集素 Synonyms: 半乳糖凝素; |
| el-GR | Greek (Greece) | Γαλεκτίνη 3 Synonyms: Γαλεκτίνη 3 |
LOINC Copyright
Copyright © 2025 Regenstrief Institute, Inc. All Rights Reserved. To the extent included herein, the LOINC table and LOINC codes are copyright © Regenstrief Institute, Inc. and the Logical Observation Identifiers Names and Codes (LOINC) Committee. See https://