LP68400-8

CD235a

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Description

Glycophorin A (MNS blood group), also known as GYPA, is a human gene. GYPA has also recently been designated CD235a (cluster of differentiation 235a). Glycophorins A (GYPA) and B (GYPB) are major sialoglycoproteins of the human erythrocyte membrane which bear the antigenic determinants for the MN and Ss blood groups. GYPA gene consists of 7 exons and has 97% sequence homology with GYPB from the 5' UTR to the coding sequence encoding the first 45 amino acids. In addition to the M or N and S or s antigens, that commonly occur in all populations, about 40 related variant phenotypes have been identified. These variants include all the variants of the Miltenberger complex and several isoforms of Sta; also, Dantu, Sat, He, Mg, and deletion variants Ena, S-s-U- and Mk. Most of the variants are the result of gene recombinations between GYPA and GYPB. Copyright Text is available under the Creative Commons Attribution/Share-Alike License. See http://creativecommons.org/licenses/by-sa/3.0/ for details. Source: Wikipedia, CD235a

Basic Part Properties

Part Name

CD235a

Part Display Name

CD235a

Part Type

Component (Describes the core component or analyte measured)

Created On

2008-04-07

Construct for LOINC Short Name

CD235a

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