LP71162-9

SOS1 gene

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Description

The SOS1 gene (son of sevenless homolog 1 (Drosophila)) [HGNC Gene ID:11187] is located on chromosome 2p21. This gene encodes a protein that is a guanine nucleotide exchange factor for RAS proteins, membrane proteins that bind guanine nucleotides and participate in signal transduction pathways. GTP binding activates and GTP hydrolysis inactivates RAS proteins. The product of this gene may regulate RAS proteins by facilitating the exchange of GTP for GDP. Mutations in this gene are associated with gingival fibromatosis 1 and Noonan syndrome type 4. [provided by RefSeq, Jul 2008] [NCBI Gene ID:6654] Source: National Center for Biotechnology Information (NCBI) Gene

Reference Information

Type	Source	Reference
Webcontent	Online Mendelian Inheritance in Man^®Copyright OMIM® and Online Mendelian Inheritance in Man® are registered trademarks of the Johns Hopkins University.	Link to OMIM

Basic Part Properties

Part Name: SOS1 gene
Part Display Name: SOS1 gene
Part Type: Component (Describes the core component or analyte measured)
Created On: 2008-09-19
Construct for LOINC Short Name: SOS1 gene

Related Codes

Code System	Code	Code Text	Code Version
HUGO Gene Nomenclature Committee (HGNC)	HGNC:11187	SOS1
National Center for Biotech Info (NCBI) Gene (National Center for Biotechnology Information (NCBI) Gene)	6654	SOS1

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Language Variants Get Info

Tag	Language	Translation
zh-CN	Chinese (China)	SOS1 基因 Synonyms: GF1;GGF1;GINGF;HGF;NS4;OTTHUMP00000128306;gingival fibromatosis, hereditary, 1;guanine nucleotide exchange factor;son of sevenless homolog 1;son of sevenless homolog 1 (Drosophila);牙龈纤维瘤病, 遗传性, 1;鸟苷酸置换因子;鸟苷酸交换因子;无七之子同系物 1;无七之子同源物 1;无七之子同系物 1 (果蝇);无七之子同源物
et-EE	Estonian (Estonia)	SOS1 geen
es-ES	Spanish (Spain)	Gen SOS1
it-IT	Italian (Italy)	SOS1, gene Synonyms: Gene SOS1
tr-TR	Turkish (Turkey)	SOS1 geni
ru-RU	Russian (Russian Federation)	SOS1 ген
nl-NL	Dutch (Netherlands)	SOS1-gen Synonyms: SOS1 gen
fr-FR	French (France)	SOS1 gène
pl-PL	Polish (Poland)	SOS1 gen Synonyms: Gen SOS1
el-GR	Greek (Greece)	Γονίδιο SOS1 Synonyms: Γονίδιο SOS1

LOINC Copyright

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