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Description

The IRF6 gene (interferon regulatory factor 6) [HGNC Gene ID:6121] is located on chromosome 1q32.3-q41. This gene encodes a member of the interferon regulatory transcription factor (IRF) family. Family members share a highly-conserved N-terminal helix-turn-helix DNA-binding domain and a less conserved C-terminal protein-binding domain. The encoded protein may be a transcriptional activator. Mutations in this gene can cause van der Woude syndrome and popliteal pterygium syndrome. Mutations in this gene are also associated with non-syndromic orofacial cleft type 6. Alternate splicing results in multiple transcript variants.[provided by RefSeq, May 2011] [NCBI Gene ID:3664] Source: National Center for Biotechnology Information (NCBI) Gene

Basic Part Properties

Part Name
IRF6 gene
Part Display Name
IRF6 gene
Part Type
Component (Describes the core component or analyte measured)
Created On
2008-10-01
Construct for LOINC Short Name
IRF6 gene

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Language Variants Get Info

TagLanguageTranslation
zh-CNChinese (China)IRF6 基因
Synonyms: 干扰素调节因子-6 基因;LPS;OFC6;PIT;PPS;VWS;OTTHUMP00000034677;interferon regulatory factor 6;干扰素调节因子-6
et-EEEstonian (Estonia)IRF6 geen
es-ESSpanish (Spain)Gen IRF6
it-ITItalian (Italy)IRF6, gene
Synonyms: Gene IRF6
tr-TRTurkish (Turkey)IRF6 geni
ru-RURussian (Russian Federation)IRF6 ген
nl-NLDutch (Netherlands)IRF6-gen
Synonyms: IRF6 gen
fr-FRFrench (France)IRF6 gène
pl-PLPolish (Poland)IRF6 gen
Synonyms: Gen IRF6
el-GRGreek (Greece)Γονίδιο IRF6
Synonyms: Γονίδιο IRF6