LP95083-9
Cathepsin S
Active
Description
Cathepsin S, also known as CTSS, is a protein which in humans is encoded by the CTSS gene. The protein encoded by this gene, a member of the peptidase C1 family, is a lysosomal cysteine protease that may participate in the degradation of antigenic proteins to peptides for presentation on MHC class II molecules. The encoded protein can function as an elastase over a broad pH range in alveolar macrophages. Transcript variants utilizing alternative polyadenylation signals exist for this gene.
Cathepsin S has been shown to be a significant prognostic factor for patients with type IV astrocytomas (glioblastoma multiforme), and its inhibition has shown improvement in survival time by mean average 5 months. This is because the cysteine enzyme can no longer act together with other proteases to break up the brain extracellular matrix. So the spread of the tumor is halted. Scientists have just announced that this enzyme predicts death, as it has been shown to be associated with both heart disease and cance
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Source: Wikipedia
, Cathepsin S
Basic Part Properties
- Part Name
- Cathepsin S
- Part Display Name
- Cathepsin S
- Part Type
- Component (Describes the core component or analyte measured)
- Created On
- 2009-06-19
- Construct for LOINC Short Name
- Cathepsin S
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Language Variants Get Info
| Tag | Language | Translation |
|---|---|---|
| es-ES | Spanish (Spain) | Catepsina S |
| it-IT | Italian (Italy) | Catepsina S |
| et-EE | Estonian (Estonia) | Katepsiin S |
| zh-CN | Chinese (China) | 组织蛋白酶 S Synonyms: CTS; |
| tr-TR | Turkish (Turkey) | Katepsin S |
| ru-RU | Russian (Russian Federation) | Катепсин S |
| fr-BE | French (Belgium) | Cathepsine S |
| fr-CA | French (Canada) | Cathepsine S |
| nl-NL | Dutch (Netherlands) | cathepsine S |
| el-GR | Greek (Greece) | Καθεψίνη S Synonyms: Καθεψίνη S |
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