LP95084-7
Cholesterol ester transfer protein
Active
Description
Cholesterol ester transfer protein (CETP), also called plasma lipid transfer protein, is a plasma protein that facilitates the transport of cholesteryl esters and triglycerides between the lipoproteins. It collects triglycerides from very low-density (VLDL) or low-density lipoproteins (LDL) and exchanges them for cholesteryl esters from high-density lipoproteins (HDL), and vice versa. Most of the time, however, CETP does a homoexchange, trading a triglyceride for a triglyceride or a cholesteryl ester for a cholesteryl ester.
Rare mutations leading to increased function of CETP have been linked to accelerated atherosclerosis. In contrast, a polymorphism (I405V) of the CETP gene leading to lower serum levels has also been linked to exceptional longevity and to metabolic response to nutritional intervention. However, this mutation also increases the prevalence of coronary heart disease in patients with hypertriglyceridemia. The D442G mutation, which lowers CETP levels and increases HDL levels also increases coronary heart disease.
Elaidic acid, a major component of trans fat, increases CETP activity.
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Source: Wikipedia
, Cholesterol ester transfer protein
Basic Part Properties
- Part Name
- Cholesterol ester transfer protein
- Part Display Name
- Cholesterol ester transfer protein
- Part Type
- Component (Describes the core component or analyte measured)
- Created On
- 2009-06-19
- Construct for LOINC Short Name
- Cholest est trnsfr prot
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Language Variants Get Info
| Tag | Language | Translation |
|---|---|---|
| es-ES | Spanish (Spain) | Proteína colesterol ester transferasa |
| it-IT | Italian (Italy) | Colesterolo, proteina trasferimento esteri Synonyms: CETP |
| tr-TR | Turkish (Turkey) | Kolesterol ester transfer protein |
| ru-RU | Russian (Russian Federation) | Холестерол эфир переносящий протеин Synonyms: Эфир-холестерин-переносящий белок |
| fr-BE | French (Belgium) | Cholesterol ester transfer protéine |
| nl-NL | Dutch (Netherlands) | cholesterolester-transfer-proteïne |
| pl-PL | Polish (Poland) | CEPT |
| zh-CN | Chinese (China) | 胆固醇酯转移蛋白 Synonyms: Cholesterol ester transfer protein; |
| el-GR | Greek (Greece) | Μεταφορική πρωτεΐνη εστέρων χοληστερόλης Synonyms: Μεταφορική πρωτεΐνη εστέρων χοληστερόλης |
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