LP95187-8
ACE gene
Active
Description
The ACE gene (angiotensin I converting enzyme) [HGNC Gene ID:2707] is located on chromosome 17q23.3. This gene encodes an enzyme involved in catalyzing the conversion of angiotensin I into a physiologically active peptide angiotensin II. Angiotensin II is a potent vasopressor and aldosterone-stimulating peptide that controls blood pressure and fluid-electrolyte balance. This enzyme plays a key role in the renin-angiotensin system. Many studies have associated the presence or absence of a 287 bp Alu repeat element in this gene with the levels of circulating enzyme or cardiovascular pathophysiologies. Multiple alternatively spliced transcript variants encoding different isoforms have been identified, and two most abundant spliced variants encode the somatic form and the testicular form, respectively, that are equally active. [provided by RefSeq, May 2010] [NCBI Gene ID:1636] Source: National Center for Biotechnology Information (NCBI) Gene
Reference Information
| Type | Source | Reference |
|---|---|---|
| Webcontent | Online Mendelian Inheritance in Man®Copyright OMIM® and Online Mendelian Inheritance in Man® are registered trademarks of the Johns Hopkins University. | Link to OMIM |
Basic Part Properties
- Part Name
- ACE gene
- Part Display Name
- ACE gene
- Part Type
- Component (Describes the core component or analyte measured)
- Created On
- 2009-06-25
- Construct for LOINC Short Name
- ACE gene
LOINC Terminology Service (API) using HL7® FHIR® Get Info
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Language Variants Get Info
| Tag | Language | Translation |
|---|---|---|
| zh-CN | Chinese (China) | ACE 基因 Synonyms: 血管紧张素转换酶基因 |
| et-EE | Estonian (Estonia) | ACE geen |
| es-ES | Spanish (Spain) | Gen ACE |
| it-IT | Italian (Italy) | ACE, gene Synonyms: Gene ACE |
| tr-TR | Turkish (Turkey) | ACE geni |
| ru-RU | Russian (Russian Federation) | ACE ген |
| nl-NL | Dutch (Netherlands) | ACE-gen Synonyms: ACE gen |
| fr-FR | French (France) | ACE gène |
| pl-PL | Polish (Poland) | ACE gen Synonyms: Gen ACE; |
| el-GR | Greek (Greece) | Γονίδιο ACE Synonyms: Γονίδιο ACE |
LOINC Copyright
Copyright © Regenstrief Institute, Inc. All Rights Reserved. To the extent included herein, the LOINC table and LOINC codes are copyright © Regenstrief Institute, Inc. and the Logical Observation Identifiers Names and Codes (LOINC) Committee. See https://