LP97958-0
Gestrinone
Active
Description
Gestrinone was developed in the early 1970s and was tested clinically as a weekly oral contraceptive in European and North American countries. ]. Without significant advantages over other oral contraceptives and with its high price, gestrinone was no longer used after the Stage II clinical trial. However, from 1982 aroused widespread interest due to substantial therapeutic effects in treating endometriosis. Under different endocrine conditions, gestrinone possesses estrogenic, progestational, androgenic, antiestrogenic and antiprogesterone actions. Starting from gestrinone, chemists can synthesize tetrahydrogestrinone (THG) in one reaction step. THG is a real designer steroid; designer steroids (chemically modified steroids) pose a threat to the integrity of the sport community. These compounds have recently been detected in urine specimens from athletes, resulting in temporary or permanent suspension from amateur and/or professional competition. PMID: 15934041, PMID: 17707720 Copyright Copyright ©2005-2009 Genome Alberta (Reference to original publication: Wishart DS, Knox C, Guo AC, et al. HMDB: a knowledgebase for the human metabolome. Nucleic Acids Res. 2009 37(Database issue):D603-610.) Source: Human Metabolome Database, Gestrinone
Basic Part Properties
- Part Name
- Gestrinone
- Part Display Name
- Gestrinone
- Part Type
- Component (Describes the core component or analyte measured)
- Created On
- 2009-11-18
- Construct for LOINC Short Name
- Gestrinone
LOINC Terminology Service (API) using HL7® FHIR® Get Info
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Language Variants Get Info
| Tag | Language | Translation |
|---|---|---|
| et-EE | Estonian (Estonia) | Gestrinoon |
| es-ES | Spanish (Spain) | Gestrinona |
| it-IT | Italian (Italy) | Gestrinone |
| tr-TR | Turkish (Turkey) | Gestrinon |
| ru-RU | Russian (Russian Federation) | Гестринон |
| nl-NL | Dutch (Netherlands) | gestrinon |
| fr-BE | French (Belgium) | Gestrinone |
| fr-FR | French (France) | Gestrinone |
| zh-CN | Chinese (China) | 孕三烯酮 Synonyms: 内美通; |
| pl-PL | Polish (Poland) | Gestrinon |
| el-GR | Greek (Greece) | Γεστρινόνη Synonyms: Γεστρινόνη |
LOINC Copyright
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