Description

Deoxyinosine is a nucleoside that is formed when hypoxanthine is attached to a deoxyribose ring (also known as a ribofuranose) via a beta-N9-glycosidic bond. Deoxyinosine is found in DNA while Inosine is found in RNA. Inosine is a nucleic acid important for RNA editing. Adenosine deaminase (ADA) catalyzes the conversion of adenosine and deoxyadenosine to inosine and deoxyinosine, respectively. ADA-deficient individuals suffer from severe combined immunodeficiency (SCID) and are unable to produce significant numbers of mature T or B lymphocytes. This occurs as a consequence of the accumulation of ADA substrates or their metabolites. Inosine is also an intermediate in a chain of purine nucleotides reactions required for muscle movements.[HMDB ID: HMDB00071] Copyright Copyright ©2005-2009 Genome Alberta (Reference to original publication: Wishart DS, Knox C, Guo AC, et al. HMDB: a knowledgebase for the human metabolome. Nucleic Acids Res. 2009 37(Database issue):D603-610.) Source: Human Metabolome Database

Basic Part Properties

Part Name
Deoxyinosine
Part Display Name
Deoxyinosine
Part Type
Component (Describes the core component or analyte measured)
Created On
2010-03-25
Construct for LOINC Short Name
Deoxyinosine

LOINC Terminology Service (API) using HL7® FHIR® Get Info

CodeSystem lookup
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Language Variants Get Info

TagLanguageTranslation
et-EEEstonian (Estonia)Deoksüinosiin
es-ESSpanish (Spain)Deoxiinosina
it-ITItalian (Italy)Deossiinosina
tr-TRTurkish (Turkey)Deoksiinozin
ru-RURussian (Russian Federation)Дезоксиинозин
nl-NLDutch (Netherlands)deoxyinosine
fr-BEFrench (Belgium)Déoxyinosine
fr-FRFrench (France)Déoxyinosine
zh-CNChinese (China)脱氧肌苷
Synonyms: 脱氧次黄苷;deoxyinosine;dI
pl-PLPolish (Poland)Deoksyinozyna
el-GRGreek (Greece)Δεοξυϊνοσίνη
Synonyms: Δεοξυϊνοσίνη