LP99927-3
Deoxyinosine
Active
Description
Deoxyinosine is a nucleoside that is formed when hypoxanthine is attached to a deoxyribose ring (also known as a ribofuranose) via a beta-N9-glycosidic bond. Deoxyinosine is found in DNA while Inosine is found in RNA. Inosine is a nucleic acid important for RNA editing. Adenosine deaminase (ADA) catalyzes the conversion of adenosine and deoxyadenosine to inosine and deoxyinosine, respectively. ADA-deficient individuals suffer from severe combined immunodeficiency (SCID) and are unable to produce significant numbers of mature T or B lymphocytes. This occurs as a consequence of the accumulation of ADA substrates or their metabolites. Inosine is also an intermediate in a chain of purine nucleotides reactions required for muscle movements.[HMDB ID: HMDB00071] Copyright Copyright ©2005-2009 Genome Alberta (Reference to original publication: Wishart DS, Knox C, Guo AC, et al. HMDB: a knowledgebase for the human metabolome. Nucleic Acids Res. 2009 37(Database issue):D603-610.) Source: Human Metabolome Database
Basic Part Properties
- Part Display Name
- Deoxyinosine
- Part Type
- Component (Describes the core component or analyte measured)
- Created On
- 2010-03-25
- Construct for LOINC Short Name
- Deoxyinosine
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Language Variants Get Info
Tag | Language | Translation |
---|---|---|
et-EE | Estonian (Estonia) | Deoksüinosiin |
es-ES | Spanish (Spain) | Deoxiinosina |
it-IT | Italian (Italy) | Deossiinosina |
tr-TR | Turkish (Turkey) | Deoksiinozin |
ru-RU | Russian (Russian Federation) | Дезоксиинозин |
nl-NL | Dutch (Netherlands) | deoxyinosine |
fr-BE | French (Belgium) | Déoxyinosine |
zh-CN | Chinese (China) | 脱氧肌苷 Synonyms: 脱氧次黄苷; |
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