Abstract
In 2018 the University Hospital of Giessen (UHG) moved its hospital information system from an in-house solution to commercial software. The introduction of MEONA and Synedra-AIM allowed for the successful migration of clinical documents. The large pool of structured clinical data has been addressed in a second step and is now consolidated in a HAPI-FHIR server and mapped to LOINC and SNOMED for semantic interoperability in multicenter research projects, especially the German Medical Informatics Initiative (MII) and the Medical Informatics in Research and Care in University Medicine (MIRACUM) consortium.