100053-8
Fluoroquinolone [Susceptibility]
Active
Part Description
LP266717-0 Fluoroquinolone
Fluorquinolones are among most beneficial drugs used to treat multi-drug resistant Mycobacterium tuberculosis (MDR-TB) infections. The fluorquinolones affect the activity of DNA gyrase by reducing the cell's ability for DNA replication and transcription. DNA gyrase in Mycobacterium tuberculosis (TB) is made of two subunits that are encoded by gyrA and gyrB. Mutations in the gyrA quinolone resistance-determining region (QRDR) are responsible for causing most of the drug resistance of TB to the fluoroquinolones. The gyrB mutations have a much smaller impact on TB resistance to the fluoroquinolones.[PMID: 26763957]
Source: Regenstrief LOINC
Fully-Specified Name
- Component
- Fluoroquinolone
- Property
- Susc
- Time
- Pt
- System
- Isolate
- Scale
- OrdQn
- Method
Additional Names
- Short Name
- FLQ Susc Islt
- Display Name
- Fluoroquinolone [Susc]
- Consumer Name Alpha
- Susceptibility to Fluoroquinolone
Example Answer List: LL360-9
Source: Regenstrief Institute| Answer | Code | Score | Answer ID |
|---|---|---|---|
| PositiveCopyright http://snomed.info/sct ID:10828004 Positive (qualifier value) | LA6576-8 | ||
| NegativeCopyright http://snomed.info/sct ID:260385009 Negative (qualifier value) | LA6577-6 |
Basic Attributes
- Class
- ABXBACT
- Type
- Laboratory
- First Released
- Version 2.72
- Last Updated
- Version 2.72
- Order vs. Observation
- Both
Member of these Groups
| LOINC Group | Group Name |
|---|---|
| LG51364-4 | FluoroquinoloneSusc| |
Language Variants
| Tag | Language | Translation |
|---|---|---|
| es-ES | Spanish (Spain) | Fluoroquinolona: |
| it-IT | Italian (Italy) | Fluorochinolone: Synonyms: |
| de-DE | German (Germany) | Fluorchinolon: |
| zh-CN | Chinese (China) | 氟喹诺酮: Synonyms: |
| nl-NL | Dutch (Netherlands) | fluorchinolon: |
LOINC Terminology Service (API) using HL7® FHIR®
Requests to this service require a free LOINC username and password. Below is a sample of the possible capabilities. See the LOINC Terminology Service documentation for more information.
- CodeSystem lookup
- https:
//fhir.loinc.org/CodeSystem/$lookup?system=http: //loinc.org&code=100053-8
Third Party Copyright
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LOINC Copyright
Copyright © 2023 Regenstrief Institute, Inc. All Rights Reserved. To the extent included herein, the LOINC table and LOINC codes are copyright