Naloxone [Presence] in Cord tissue by Screen method
Naloxone is a pure opioid antagonist and, when taken at recommended doses, has no physiological effects in the absence of an opioid agonist. Intravenous naloxone becomes effective within two minutes of injection, but oral or sublingual naloxone has little effect due to its poor absorption. Therefore, intravenous naloxone is used to treat opioid overdose, and it is used as a sublingual combination with buprenorphine, an opioid agonist-antagonist used to treat chronic opioid-dependence, to lower buprenorphine's abuse potential as follows: when the combination is taken sublingually as prescribed, naloxone exerts little effect and buprenorphine's effects predominate; however, if crushed and injected intravenously, naloxone's antagonist properties reverse the agonist effects of buprenorphine and can precipitate withdrawal. PMID: 19368419 Nalaxone levels along with its inactive metabolite, naloxone-3-glucuronide (N3G), may be measured to monitor compliance or identify illicit opioid drug use. Source: Regenstrief LOINC, PMID: 19368419
- Short Name
- Naloxone TissCo Ql Scn
- Display Name
- Naloxone Screen Ql (Umb cord tissue)
- Consumer Name Alpha Get Info
- Naloxone, Umbilical cord tissue
Example Answer List: LL2872-1Source: Laboratory Corporation of America
|PresentCopyright http://snomed.info/sct ID:52101004 Present (qualifier value)||LA9633-4|
- First Released
- Version 2.73
- Last Updated
- Version 2.73
- Order vs. Observation
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Synonyms: Livelli farmacologici e tossicologia Presenza o Soglia Punto nel tempo (episodio) Screening tossicologico Tessuto del cordone ombelicale
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