Version 2.77

Part Description

LP32397-9   Ab.IgG4
IgG4 is the least common subtype of IgG, and it has a variety of functions. In the context of allergic disease it is thought to have an immune-inhibitory role in preventing anaphylaxis and is commonly known as a "blocking" antibody. IgG4 binding to an allergen can compete with IgE-mediated binding, thereby inhibiting the activation of mast cells and basophils and IgE-mediated presentation to T-cells. Measuring IgG4 and its ratio to IgE has a role in monitoring allergen specific immunotherapy PMID: 26023323. IgG4 is also thought to have a role in autoimmunity and be involved in a less defined entity known as IgG4-Related Disease, a chronic immune-mediated fibroinflammatory disorder that often manifests with tumor-like masses .[https://www.merckmanuals.com/professional/musculoskeletal-and-connective-tissue-disorders/igg4-related-disease/igg4-related-disease] Source: Regenstrief LOINC

Fully-Specified Name

Component
Neurofascin155 Ab.IgG4
Property
PrThr
Time
Pt
System
Ser
Scale
Ord
Method
Flow cytometry

Additional Names

Short Name
Neurofascin155 IgG4 Ser Ql FC
Display Name
Neurofascin155 IgG4 FC Ql (S)
Consumer Name Alpha Get Info
Neurofascin155 IgG4 antibody, Blood

Example Answer List: LL360-9

Source: Regenstrief Institute
Answer Code Score Answer ID
PositiveCopyright http://snomed.info/sct ID:10828004 Positive (qualifier value) LA6576-8
NegativeCopyright http://snomed.info/sct ID:260385009 Negative (qualifier value) LA6577-6

Basic Attributes

Class
SERO
Type
Laboratory
First Released
Version 2.73
Last Updated
Version 2.73
Order vs. Observation
Both

Member of these Panels

LOINC Long Common Name
101447-1 Contactin-associated protein 1 Ab.IgG and Neurofascin155 Ab.IgG4 panel - Serum or Plasma

Language Variants Get Info

Tag Language Translation
es-ES Spanish (Spain) Neurofascina155 IgG4:PrThr:Punto temporal:Suero:Ord:Citometria de flujo (FC)
fr-FR French (France) Neurofascine155 Ac IgG4:Présence/Seuil:Ponctuel:Sérum:Qualitatif:Cytométrie de flux
it-IT Italian (Italy) Neurofascina155 Ab.IgG4:PrThr:Pt:Siero:Ord:Citometria a flusso
Synonyms: Anticorpi IgG4 anticorpo Citometria a flusso (FC) Neurofascina 155 Presenza o Soglia Punto nel tempo (episodio) Siero Sierologia (anticorpi e la maggior parte degli ant
nl-NL Dutch (Netherlands) neurofascine155 As.IgG4:aanwezigheid:moment:serum:ordinaal:flowcytometrie
Synonyms: antistof; antilichaam
zh-CN Chinese (China) 神经束蛋白 155 抗体.IgG4:存在情况或阈值:时间点:血清:序数型:流式细胞测量术
Synonyms: Ab.IgG4;IgG4;抗体 IgG4 Ab;自身抗体 Neurofascin-155;神经束蛋白-155;Nfasc155;NF-155 依次型;分类顺序型;定性的;序数型（或称等级型）;性质上的;有序型;有序性分类应答;有序性分类结果;秩次型;等级型;筛查;顺序型 动态 存在情况;存在;存在与否;是否存在;阈值;界值;界限;阀值;临界值;存在情况（存在、存在与否、是否存在）或阈值（界值、界限、阀值、临界值） 时刻;随机;随意;瞬间 流 流式细胞光度计;流式细胞测量术（Flow Cytometry，FC）;流式细胞计 血清;血清学;血清学检验项目;血清学检验项目 (非微生物学);血清学检验项目（非微生物学）;血清学检验项目类;血清学检验项目类 (非微生物学);血清学类;血清学类检验项目;血清学类检验项目 (非微生物学);血清学类试验;血清学类试验 (非微生物学);血清学试验;血清学试验 (非微生物学);血清学试验（非微生物学）;血清学试验类 (非微生物学);血清类

LOINC Terminology Service (API) using HL7® FHIR® Get Info

CodeSystem lookup
https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=100845-7