100845-7
Neurofascin155 IgG4 Ab [Presence] in Serum by Flow cytometry (FC)
Active
Part Description
LP32397-9 Ab.IgG4
IgG4 is the least common subtype of IgG, and it has a variety of functions. In the context of allergic disease it is thought to have an immune-inhibitory role in preventing anaphylaxis and is commonly known as a "blocking" antibody. IgG4 binding to an allergen can compete with IgE-mediated binding, thereby inhibiting the activation of mast cells and basophils and IgE-mediated presentation to T-cells. Measuring IgG4 and its ratio to IgE has a role in monitoring allergen specific immunotherapy PMID: 26023323. IgG4 is also thought to have a role in autoimmunity and be involved in a less defined entity known as IgG4-Related Disease, a chronic immune-mediated fibroinflammatory disorder that often manifests with tumor-like masses .[https://www.merckmanuals.com/professional/musculoskeletal-and-connective-tissue-disorders/igg4-related-disease/igg4-related-disease]
Source: Regenstrief LOINC
Fully-Specified Name
- Component
- Neurofascin155 Ab.IgG4
- Property
- PrThr
- Time
- Pt
- System
- Ser
- Scale
- Ord
- Method
- Flow cytometry
Additional Names
- Short Name
- Neurofascin155 IgG4 Ser Ql FC
- Display Name
- Neurofascin155 IgG4 FC Ql (S)
- Consumer Name Alpha Get Info
- Neurofascin155 IgG4 antibody, Blood
Example Answer List: LL360-9
Source: Regenstrief InstituteAnswer | Code | Score | Answer ID |
---|---|---|---|
PositiveCopyright http://snomed.info/sct ID:10828004 Positive (qualifier value) | LA6576-8 | ||
NegativeCopyright http://snomed.info/sct ID:260385009 Negative (qualifier value) | LA6577-6 |
Basic Attributes
- Class
- SERO
- Type
- Laboratory
- First Released
- Version 2.73
- Last Updated
- Version 2.73
- Order vs. Observation
- Both
Member of these Panels
LOINC | Long Common Name |
---|---|
101447-1 | Contactin-associated protein 1 Ab.IgG and Neurofascin155 Ab.IgG4 panel - Serum or Plasma |
Language Variants Get Info
Tag | Language | Translation |
---|---|---|
es-ES | Spanish (Spain) | Neurofascina155 IgG4: |
fr-FR | French (France) | Neurofascine155 Ac IgG4: |
it-IT | Italian (Italy) | Neurofascina155 Ab.IgG4: Synonyms: Anticorpi IgG4 anticorpo Citometria a flusso (FC) Neurofascina 155 Presenza o Soglia Punto nel tempo (episodio) Siero Sierologia (anticorpi e la maggior parte degli ant |
nl-NL | Dutch (Netherlands) | neurofascine155 As.IgG4: Synonyms: antistof; |
zh-CN | Chinese (China) | 神经束蛋白 155 抗体.IgG4: Synonyms: Ab.IgG4; |
LOINC Terminology Service (API) using HL7® FHIR® Get Info
Requests to this service require a free LOINC username and password. Below is a sample of the possible capabilities. See the LOINC Terminology Service documentation for more information.
- CodeSystem lookup
- https:
//fhir.loinc.org/CodeSystem/$lookup?system=http: //loinc.org&code=100845-7
Third Party Copyright
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LOINC Copyright
Copyright © 2024 Regenstrief Institute, Inc. All Rights Reserved. To the extent included herein, the LOINC table and LOINC codes are copyright