101303-6
Chikungunya virus RNA [Presence] in Blood by NAA with non-probe detection
Active
Part Descriptions
LP21132-3 Chikungunya virus
A species of ALPHAVIRUS causing an acute dengue-like fever.
Source: National Library of Medicine, MeSH 2006
LP21132-3 Chikungunya virus
Chikungunya virus (CHIKV) belongs to the mosquito-borne alphavirus genus, in the family Togaviridae, and was first observed in epidemic form in Africa. Serologically, CHIKV belongs to the Semliki Forest (SF) subgroup of alphaviruses. Infection in humans is characterized by rash, high fever and, its hallmark feature, severe arthritis that can persist for years. CHIKV is a small, spherical, enveloped, positive-strand RNA virus. The virion consists of an envelope and a nucleocapsid. The envelope glycoproteins of alphaviruses are the distinguishing factors for testing. The CHIKV genome encodes for two polyproteins; the non-structural polyprotein consisting of four proteins (nsP1, nsP2, nsP3 and nsP4) and the structural polyprotein consisting of five proteins (Capsid, E3, E2, 6K and E1). CHIKV has spikes on the virion surface that are each formed by three E1-E2 heterodimers, where the E1 glycoproteins mediate fusion and E2 glycoproteins interact with the host receptor. PMID: 20111039
CHIKV can be detected between the first and fourth day of infection (the acute phase) using PCR or virus cultivation, and virus-specific IgM and IgG antibodies can be detected during the 8th to the 10th day of infection. Antibody investigation should be performed using serum samples from the acute and convalescent stage.
Source: Regenstrief LOINC
Fully-Specified Name
- Component
- Chikungunya virus RNA
- Property
- PrThr
- Time
- Pt
- System
- Bld
- Scale
- Ord
- Method
- Non-probe.amp.tar
Additional Names
- Short Name
- CHIKV RNA Bld Ql NAA+non-probe
- Display Name
- CHIKV RNA NAA+non-probe Ql (Bld)
- Consumer Name Alpha Get Info
- Chikungunya virus, Blood
Example Answer List: LL744-4
Source: Regenstrief InstituteAnswer | Code | Score | Answer ID |
---|---|---|---|
Detected | LA11882-0 | ||
Not detected | LA11883-8 |
Basic Attributes
- Class
- MICRO
- Type
- Laboratory
- First Released
- Version 2.74
- Last Updated
- Version 2.75
- Order vs. Observation
- Both
Member of these Panels
LOINC | Long Common Name |
---|---|
101344-0 | Acute febrile illness global pathogens panel - Blood by NAA with non-probe detection |
Member of these Groups Get Info
LOINC Group | Group Name |
---|---|
LG51028-5 | Chikungunya virus |
Language Variants Get Info
Tag | Language | Translation |
---|---|---|
de-DE | German (Germany) | Chikungunya-Virus RNA: |
es-ES | Spanish (Spain) | Virus Chikungunya RNA: |
fr-CA | French (Canada) | Virus Chikungunya ARN: |
fr-FR | French (France) | Chikungunya virus ARN: |
it-IT | Italian (Italy) | Chikungunya virus RNA: Synonyms: Amplificazione target non basata su sonda CHIK Microbiologia Presenza o Soglia Punto nel tempo (episodio) Sangue Sonda con amplificazione Sonda con amplificazione del target Sonda di DNA |
zh-CN | Chinese (China) | 基孔肯亚病毒 RNA: Synonyms: 传染毒; |
LOINC Terminology Service (API) using HL7® FHIR® Get Info
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- CodeSystem lookup
- https:
//fhir.loinc.org/CodeSystem/$lookup?system=http: //loinc.org&code=101303-6
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