Version 2.78

Part Description

LP14853-3   Varicella zoster virus
Varicella zoster virus (VZV) is a double-stranded alphaherpesvirus that causes seasonal outbreaks of chickenpox and shingles in non-immunized populations. VZV is highly infectious and is transmitted by contact with the ruptured fluid filled blisters and respiratory secretions of infected individuals. Immunity post infection is usually lifelong though the latent virus inhabits the sensory nerve ganglia where it can reactivate causing shingles when immunity declines with aging.[http://jvi.asm.org/content/88/24/13936.full] In the over fifty strains of VZV that have been sequenced it has been found that a single nucleotide polymorphism occurs about every 100 bases. The patterns of polymorphisms in VZV correlate with different geographical regions of infection and is the basis for the classification of viral clades.[https://grose.lab.uiowa.edu/vzv-genomes-and-evolution] Breuer proposed the nomenclature for the VZV clades as 1-5 with the suspected clades VI and VII to be confirmed later. The geographical regions associated with the seven clades are as follows:
Clades 1 and 3-represent the dominant clades of the circulating VZV in Europe and the Americas
Clades 4 and 5-found in Africa
Clade VI found in France, Italy
Clade VII exclusively isolated in the US
Clade 2-Asia from Korea, Japan, China not found in India, Nepal and Bangladesh where clades 4 and 5 were dominant
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5054591/ Source: Regenstrief LOINC

Fully-Specified Name

Component
Varicella zoster virus DNA
Property
PrThr
Time
Pt
System
Respiratory System Specimen
Scale
Ord
Method
Probe.amp.tar

Additional Names

Short Name
VZV DNA Resp Ql NAA+probe
Display Name
VZV DNA NAA+probe Ql (Respiratory system specimen)
Consumer Name Alpha Get Info
Varicella zoster virus (VZV; Chickenpox), Respiratory system specimen

Example Answer List: LL744-4

Source: Regenstrief Institute
Answer Code Score Answer ID
Detected LA11882-0
Not detected LA11883-8

Basic Attributes

Class
MICRO
Type
Laboratory
First Released
Version 2.74
Last Updated
Version 2.75
Change Reason
Release 2.75: SYSTEM: There are 2 similar system's in LOINC: 1- Respiratory system 2- Respiratory specimen Due to an applied logic, the display in the System axis for 1 is Respiratory (adjective) without specification of sample, specimen, or other specific noun, while 2 is displayed fully as Respiratory specimen. Therefore for now we replaced 1 with Respiratory system specimen, which will affect 83 term. The result is replacing "Respiratory" with "Respiratory system specimen". This is the short approach. The bigger project is to potentially merge data that has either 1 or 2 together. This is a project to pass by the laboratory committee and will involve about 1500 concepts.;
Order vs. Observation
Both

Member of these Groups Get Info

LOINC Group Group Name
LG32750-8 Varicella zoster virus
LG50851-1 Varicella zoster virus DNA|PrThr|Sys:ANYResp

Language Variants Get Info

Tag Language Translation
es-ES Spanish (Spain) Virus Varicella zoster ADN:PrThr:Punto temporal:Muestra del sistema respiratorio:Ord:Sonda con amplificación dirigida
Synonyms: Muestra del tracto respiratorio Muestra respiratoria Tracto respiratorio
fr-CA French (Canada) Virus varicelle-zona, ADN:Présence-Seuil:Temps ponctuel:Échantillon du système respiratoire:Ordinal:Sonde avec amplification de la cible
fr-FR French (France) Varicelle zona virus ADN:Présence/Seuil:Ponctuel:Échantillon du système respiratoire:Qualitatif:PCR amplification de cible
it-IT Italian (Italy) Varicella zoster, virus DNA:PrThr:Pt:Campione da Sistema Respiratorio:Ord:Sonda.amp.tar
Synonyms: Campione da Apparato Respiratorio Microbiologia Presenza o Soglia Punto nel tempo (episodio) Sonda con amplificazione Sonda con amplificazione del target Sonda di DNA Virus della varicella zoster
nl-NL Dutch (Netherlands) varicella-zostervirus DNA:aanwezigheid:moment:respiratoir monster:ordinaal:probe-detectie
Synonyms: probe.amp.tar systema respiratorium; ademhalingsstelsel Varicella zoster virus
zh-CN Chinese (China) 水痘带状疱疹病毒 DNA:存在情况或阈值:时间点:呼吸系统标本:序数型:探针法.基因扩增.靶向
Synonyms: HHV-3 DNA HHV-3;VZ;VZV;人类疱疹病毒 3 型;人类疱疹病毒 III 型;带状疱疹;水痘;水痘带状疱疹;水痘病毒;Varicella zoster virus;水痘-带状疱疹病毒 VZV DNA 人类疱疹病毒 3 型 DNA 人类疱疹病毒 III 型 DNA 传染毒;传染毒素;滤过性病原体;病毒类;过滤性病原体 供检查用的材料;待检物;待试验物;样品;样本;试料;试样 依次型;分类顺序型;定性的;序数型（或称等级型）;性质上的;有序型;有序性分类应答;有序性分类结果;秩次型;等级型;筛查;顺序型 借助扩增的探针方法;借助扩增的探针法;探针法.扩增 借助靶向扩增的探针方法;借助靶向扩增的探针法;探针法.扩增.靶向 去氧核糖核酸;脱氧核糖核酸 去氧核糖核酸;脱氧核糖核酸;脱氧核糖核酸（Deoxyribonucleic acid，DNA） 受检物 呼吸道标本（样品、样本）;呼吸系统标本（样品、样本） 存在情况;存在;存在与否;是否存在;阈值;界值;界限;阀值;临界值;存在情况（存在、存在与否、是否存在）或阈值（界值、界限、阀值、临界值） 微生物学;微生物学试验;微生物学试验（培养、DNA、抗原及抗体） 扩增型 扩增性 时刻;随机;随意;瞬间 样品 样本 水痘病毒 DNA 经过扩增的 脱氧核糖核酸探针 试样

LOINC Terminology Service (API) using HL7® FHIR® Get Info

CodeSystem lookup
https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=101428-1