101746-6
PCA-Tr Ab [Presence] in Serum by Cell binding immunofluorescent assay
Active
Part Descriptions
LP269367-1 CBA IFA
In cell binding assays or cell-based assays (CBA) also known as cell-based immunoassays, the DNA coding for a particular antigen is transfected into cultured cells, which are then used directly as substrate for antibody detection by immunofluorescence. The advantage of CBA IFA over conventional immunoassays is that purification and stability of the antigen is not required and they provide an in vivo substrate.
Source: Regenstrief LOINC,
LP31709-6 Purkinje cell cytoplasmic type Tr
Purkinje cell cytoplasmic-Tr (PCA-Tr) antibodies are associated with Hodgkin's lymphoma. The clinical presentation that corresponds with PCA-Tr antibodies includes paraneoplastic cerebellar degeneration (PCD) and limbic encephalopathy (LE). PMID: 22412264 PCD and LE are types of paraneoplastic neurological syndrome (PNS), an autoimmune disorder that is manifested by progressive neurological syndromes of any combination of the central, peripheral and autonomic nervous systems. The antibodies that attack the neural tissue develop in response to tumor cells. The neurological symptoms include encephalitis, autonomic failure, peripheral neuropathy, cerebellar ataxia, visual complaints and more. The neoplasm may or may not be detectable using conventional imaging modalities. Since PNS can be associated with multiple antibodies, testing usually includes a panel of PNS antibodies. In addition, the different PNS antibodies are associated with certain cancers so the antibody pattern can assist in identifying the specific tumor if it was previously undiagnosed. PMID: 22412264
Source: Regenstrief LOINC
LP39528-2 Purkinje cell cytoplasmic type Tr Ab
Purkinje cell cytoplasmic-Tr (PCA-Tr) antibodies are associated with Hodgkin's lymphoma. The clinical presentation that corresponds with PCA-Tr antibodies includes paraneoplastic cerebellar degeneration (PCD) and limbic encephalopathy (LE). PMID: 22412264 PCD and LE are types of paraneoplastic neurological syndrome (PNS), an autoimmune disorder that is manifested by progressive neurological syndromes of any combination of the central, peripheral and autonomic nervous systems. The antibodies that attack the neural tissue develop in response to tumor cells. The neurological symptoms include encephalitis, autonomic failure, peripheral neuropathy, cerebellar ataxia, visual complaints and more. The neoplasm may or may not be detectable using conventional imaging modalities. Since PNS can be associated with multiple antibodies, testing usually includes a panel of PNS antibodies. In addition, the different PNS antibodies are associated with certain cancers so the antibody pattern can assist in identifying the specific tumor if it was previously undiagnosed. PMID: 22412264
Source: Regenstrief LOINC
Fully-Specified Name
- Component
- Purkinje cell cytoplasmic type Tr Ab
- Property
- PrThr
- Time
- Pt
- System
- Ser
- Scale
- Ord
- Method
- CBA IFA
Additional Names
- Short Name
- PCA-Tr Ab Ser Ql CBA IFA
- Display Name
- PCA-Tr Ab Cell binding immunofluorescent assay Ql (S)
- Consumer Name Alpha Get Info
- PCA-Tr antibody, Blood
Example Answer List: LL3950-4
Source: Regenstrief LOINCAnswer | Code | Score | Answer ID |
---|---|---|---|
PresentCopyright http://snomed.info/sct ID:52101004 Present (qualifier value) | LA9633-4 | ||
AbsentCopyright http://snomed.info/sct ID:2667000 Absent (qualifier value) | LA9634-2 |
Basic Attributes
- Class
- MICRO
- Type
- Laboratory
- First Released
- Version 2.75
- Last Updated
- Version 2.75
- Order vs. Observation
- Both
Language Variants Get Info
Tag | Language | Translation |
---|---|---|
es-ES | Spanish (Spain) | Células de Purkinje tipo Tr Anticuerpos: |
fr-FR | French (France) | Tr anticorps: |
it-IT | Italian (Italy) | Cellule di Purkinje tipo Tr Ab: Synonyms: anticorpo Fluorescenza indiretta degli anticorpi (IFA) Microbiologia Presenza o Soglia Punto nel tempo (episodio) Siero |
pl-PL | Polish (Poland) | Cytoplazmatyczne typu Tr komórek Purkinjego Ab: Synonyms: Przeciwciała typu Tr do cytoplazmy komórki Purkinjego |
zh-CN | Chinese (China) | 浦肯雅细胞胞浆 Tr 型 抗体: Synonyms: Ab; |
LOINC Terminology Service (API) using HL7® FHIR® Get Info
Requests to this service require a free LOINC username and password. Below is a sample of the possible capabilities. See the LOINC Terminology Service documentation for more information.
- CodeSystem lookup
- https:
//fhir.loinc.org/CodeSystem/$lookup?system=http: //loinc.org&code=101746-6
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