102923-0
Alternaria alternata IgG4 Ab [Presence] in Serum by Radioallergosorbent test (RAST)
Active
Part Descriptions
LP13946-6 Alternaria alternata
A. alternate is a mold, a member of the imperfect fungi family, and one of the main allergens affecting children. Multiple allergens have been identified in A. alternata and the presence of specific allergens is highly dependent on growth conditions. Sensitivity to Alternaria is increasingly recognized as a risk factor for the development, persistence, and exacerbation of asthma.
In temperate climates, airborne Alternaria spores are found from May to November, peaking in late summer and autumn. The highest concentrations of spores are in grain-growing areas, such as the Midwest of the United States. A. alternata commonly grows on vegetation, soils, corn silage, rotten wood, compost, and bird nests, as well as on food and textiles.
Copyright Copyright © 2006 Phadia AB.
Source: ImmunoCap,
LP32397-9 Ab.IgG4
IgG4 is the least common subtype of IgG, and it has a variety of functions. In the context of allergic disease it is thought to have an immune-inhibitory role in preventing anaphylaxis and is commonly known as a "blocking" antibody. IgG4 binding to an allergen can compete with IgE-mediated binding, thereby inhibiting the activation of mast cells and basophils and IgE-mediated presentation to T-cells. Measuring IgG4 and its ratio to IgE has a role in monitoring allergen specific immunotherapy PMID: 26023323. IgG4 is also thought to have a role in autoimmunity and be involved in a less defined entity known as IgG4-Related Disease, a chronic immune-mediated fibroinflammatory disorder that often manifests with tumor-like masses .[https://www.merckmanuals.com/professional/musculoskeletal-and-connective-tissue-disorders/igg4-related-disease/igg4-related-disease]
Source: Regenstrief LOINC
Fully-Specified Name
- Component
- Alternaria alternata Ab.IgG4
- Property
- PrThr
- Time
- Pt
- System
- Ser
- Scale
- SemiQn
- Method
- RAST
Additional Names
- Long Common Name
- Alternaria alternata IgG4 Ab [Presence] in Serum by Radioallergosorbent test (RAST)
- Short Name
- A alternata IgG4 RAST
- Display Name
- A. alternata IgG4 RAST (S) [Presence]
- Consumer Name Alpha Get Info
- Alternaria alternata IgG4 antibody
Example Answer List: LL1927-4
Source: Wikipedia- Link to External List
- http://en.wikipedia.org/wiki/RAST_test
Answer | Code | Score | Answer ID |
---|---|---|---|
0 | LA6111-4 | ||
1 | LA6112-2 | ||
2 or more | LA6113-0 | ||
3 | LA6114-8 | ||
4 | LA6115-5 | ||
5 | LA10137-0 | ||
6 | LA10138-8 |
Basic Attributes
- Class
- ALLERGY
- Type
- Laboratory
- First Released
- Version 2.75
- Last Updated
- Version 2.75
- Order vs. Observation
- Observation
Language Variants Get Info
Tag | Language | Translation |
---|---|---|
de-DE | German (Germany) | Alternaria alternata Ak.IgG4: |
es-ES | Spanish (Spain) | Alternaria alternata IgG4: Synonyms: Semicuantitativo |
fr-CA | French (Canada) | Alternaria alternata, IgG4: |
fr-FR | French (France) | Alternaria alternata Ac IgG4: |
it-IT | Italian (Italy) | Alternaria alternata Ab.IgG4: Synonyms: Anticorpi IgG4 anticorpo Presenza o Soglia Punto nel tempo (episodio) Risposta agli antigeni Siero Test di radioallergoassorbimento (RAST) |
nl-NL | Dutch (Netherlands) | Alternaria alternata As.IgG4: Synonyms: antistof; |
zh-CN | Chinese (China) | 链格孢 抗体.IgG4: Synonyms: Ab.IgG4; |
LOINC Terminology Service (API) using HL7® FHIR® Get Info
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- CodeSystem lookup
- https:
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LOINC Copyright
Copyright © 2024 Regenstrief Institute, Inc. All Rights Reserved. To the extent included herein, the LOINC table and LOINC codes are copyright © Regenstrief Institute, Inc. and the Logical Observation Identifiers Names and Codes (LOINC) Committee. See https://