102925-5
Honey bee IgG4 Ab [Presence] in Serum by Radioallergosorbent test (RAST)
Active
Part Descriptions
LP17179-0 Apis mellifera
The natural range of the honeybee is thought to be Africa, Europe and the Middle East for A. mellifera and Japan, India and Indochina for A. cerona. Honeybees have been domesticated and spread throughout the world. Honeybee is the only stinging Hymenoptera that almost always leaves its fluked stinger in the skin of the victim. The venom continues to pump into the victim until the venom sac is exhausted or the stinger removed.
Venoms from honeybees and bumblebees are reported to be highly cross-reactive, which is consistent with the degree of structural similarity in the phospholipases, phospholipase A2. The hyaluronidases and phosphatases also have a high degree of similarity in honeybees and bumblebees.
Copyright Copyright © 2006 Phadia AB.
Source: ImmunoCap, ImmunoCap
LP32397-9 Ab.IgG4
IgG4 is the least common subtype of IgG, and it has a variety of functions. In the context of allergic disease it is thought to have an immune-inhibitory role in preventing anaphylaxis and is commonly known as a "blocking" antibody. IgG4 binding to an allergen can compete with IgE-mediated binding, thereby inhibiting the activation of mast cells and basophils and IgE-mediated presentation to T-cells. Measuring IgG4 and its ratio to IgE has a role in monitoring allergen specific immunotherapy PMID: 26023323. IgG4 is also thought to have a role in autoimmunity and be involved in a less defined entity known as IgG4-Related Disease, a chronic immune-mediated fibroinflammatory disorder that often manifests with tumor-like masses .[https://www.merckmanuals.com/professional/musculoskeletal-and-connective-tissue-disorders/igg4-related-disease/igg4-related-disease]
Source: Regenstrief LOINC
Fully-Specified Name
- Component
- Apis mellifera Ab.IgG4
- Property
- PrThr
- Time
- Pt
- System
- Ser
- Scale
- SemiQn
- Method
- RAST
Additional Names
- Short Name
- Honey bee IgG4 RAST
- Display Name
- Honey bee IgG4 RAST (S) [Presence]
- Consumer Name Alpha Get Info
- Honey bee IgG4 antibody
Example Answer List: LL1927-4
Source: Wikipedia- Link to External List
- http://en.wikipedia.org/wiki/RAST_test
Answer | Code | Score | Answer ID |
---|---|---|---|
0 | LA6111-4 | ||
1 | LA6112-2 | ||
2 or more | LA6113-0 | ||
3 | LA6114-8 | ||
4 | LA6115-5 | ||
5 | LA10137-0 | ||
6 | LA10138-8 |
Basic Attributes
- Class
- ALLERGY
- Type
- Laboratory
- First Released
- Version 2.75
- Last Updated
- Version 2.75
- Order vs. Observation
- Observation
Language Variants Get Info
Tag | Language | Translation |
---|---|---|
de-DE | German (Germany) | Apis mellifera Ak.IgG4: |
es-ES | Spanish (Spain) | Abeja de la miel (Apis mellifera) IgG4: Synonyms: Semicuantitativo |
fr-CA | French (Canada) | Apis mellifera, IgG4: |
fr-FR | French (France) | Abeille (venin) Ac IgG4: |
it-IT | Italian (Italy) | Apis mellifera Ab.IgG4: Synonyms: Anticorpi IgG4 anticorpo Ape (Apis mellifera) Presenza o Soglia Punto nel tempo (episodio) Risposta agli antigeni Siero Test di radioallergoassorbimento (RAST) |
nl-NL | Dutch (Netherlands) | Apis mellifera (honingbij) As.IgG4: Synonyms: antistof; |
zh-CN | Chinese (China) | 意大利蜜蜂 抗体.IgG4: Synonyms: Ab.IgG4; |
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- CodeSystem lookup
- https:
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