103691-2

MDA5 Ab [Units/volume] in Serum by Immunoassay

Active

Part Description

LP220403-2 MDA5
MDA5, more formally known as interferon-induced helicase C domain-containing protein 1, is an immune receptor for viral nucleic acids and plays a major role in activating antiviral responses, including the induction of type I interferons and proinflammatory cytokines. Anti-MDA5 autoantibodies, also known as anti-CADM-140, are associated with autoimmune disorders including dermatomyositis and interstitial lung disease. [UniProt: Q9BYX4] Anti-MDA5 autoantibodies are also found in a subset of patients with juvenile dermatomyositis (JDM) who have polyarthritis and ulcerative skin disease but milder muscle disease. Anti-MDA5 assays may be useful during the work-up of patients with inflammatory disorders and may help guide treatment. PMID: 24989778 Source: Regenstrief LOINC, PMID: 24989778

LOINC Names Get Info

Fully-Specified Name: MDA5 Ab:ACnc:Pt:Ser:Qn:IA
Long Common Name: MDA5 Ab [Units/volume] in Serum by Immunoassay
Short Name: MDA5 Ab Ser IA-aCnc
Display Name: MDA5 Ab IA Qn (S)
Consumer Name Alpha Get Info: MDA5 antibody, Blood

Part Model Get Info

Component
MDA5 Ab
LP220404-0
- Analyte
  MDA5 Ab
  LP220404-0
  - Component Numerator
    MDA5 Ab
    LP220404-0
    - Component Numerator Core
      MDA5
      LP220403-2
    - Component Numerator Core Suffix
      Ab
      LP20667-9
  - Component Denominator
    NULL
    - Component Denominator Core
      NULL
    - Component Denominator Core Suffix
      NULL
- Challenge
  NULL
- Adjustment
  NULL
- Count
  NULL
Property
ACnc
LP6773-8
Time
Pt
LP6960-1
- Time Core
  Pt
  LP6960-1
- Time Modifier
  NULL
System
Ser
LP7567-3
- System Core
  Ser
  LP7567-3
- Super System
  NULL
Scale
Qn
LP7753-9
Method
IA
LP217197-5

Basic Attributes

Class: SERO
Type: Laboratory
First Released: Version 2.77
Last Updated: Version 2.77 (ADD)
Order vs. Observation: Both

Member of these Groups Get Info

LOINC Group	Group Name
LG51600-1	MDA5 Ab\|ACnc\|Pt\|ANYBldSerPl

Language Variants Get Info

Tag	Language	Translation
cs-CZ	Czech (Czechia)	MDA5 Ab:Arbitrární koncentrace:Časový bod:Sérum:Kvantitativní:Imunoanalýza
el-GR	Greek (Greece)	MDA5 Αντίσωμα:ACnc:Pt:Ορός:Qn:IA Synonyms: ACnc IA MDA5 Pt Qn SERO Αντίσωμα Ορός
es-ES	Spanish (Spain)	MDA5 Anticuerpos:Concentración arbitraria:Punto temporal:Suero:Qn:IA Synonyms: Cuantitativo
fr-FR	French (France)	MDA5 Ac:Arbitraire/Volume:Ponctuel:Sérum:Numérique:Immunoanalyse
it-IT	Italian (Italy)	MDA5 Ab:ACnc:Pt:Siero:Qn:IA Synonyms: anticorpo Concentrazione Arbitraria Immunoassay Punto nel tempo (episodio) Siero Sierologia (anticorpi e la maggior parte degli ant
nl-NL	Dutch (Netherlands)	MDA5 As:eenheid/volume:moment:serum:kwantitatief:immunoassay Synonyms: antistof; antilichaam IA
zh-CN	Chinese (China)	MDA5 抗体:任意型浓度:时间点:血清:定量型:免疫测定法 Synonyms: Ab;自身抗体任意型浓度(单位体积);任意浓度;单位体积的任意单位数;人工型浓度免疫测定;免疫分析法;免疫检定法;免疫检定;免疫试验;酶免疫测定法;酶免疫测定;酶免疫分析法;酶免疫检定法;酶免疫检定;酶免疫试验可用数量表示的;定量性;数值型;数量型;连续数值型标尺干扰素诱导型解旋酶 C 结构域包含型蛋白 1;interferon-induced helicase C domain-containing protein 1 时刻;随机;随意;瞬间血清;血清学;血清学检验项目;血清学检验项目 (非微生物学);血清学检验项目（非微生物学）;血清学检验项目类;血清学检验项目类 (非微生物学);血清学类;血清学类检验项目;血清学类检验项目 (非微生物学);血清学类试验;血清学类试验 (非微生物学);血清学试验;血清学试验 (非微生物学);血清学试验（非微生物学）;血清学试验类 (非微生物学);血清类

Example Units

Unit	Source
[arb'U]/mL	Example UCUM Units

LOINC Terminology Service (API) using HL7^® FHIR^® Get Info

CodeSystem lookup: https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=103691-2

LOINC Copyright

Copyright © Regenstrief Institute, Inc. All Rights Reserved. To the extent included herein, the LOINC table and LOINC codes are copyright © Regenstrief Institute, Inc. and the Logical Observation Identifiers Names and Codes (LOINC) Committee. See https://loinc.org/license for the full LOINC copyright and license.