104259-7

Fibroblast growth factor 23 [Presence] in Tissue by FISH

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Part Descriptions

LP40488-6 Fibroblast growth factor 23
Fibroblast growth factor 23, or FGF23, is primarily produced in bone and helps regulate phosphate and vitamin D metabolism by binding to receptors on renal tubular cells. It is produced as a 251-amino acid precursor consisting of a signal peptide, N-terminal domain, and C-terminal domain. The bioactive form of FGF23 consists of the N- and C-terminal domains, after the signal peptide is removed, and is also called the "intact" form. Intact FGF23 is cleaved into N-terminal and C-terminal fragments, which are no longer active, though the C-terminal fragment may compete with intact FGF23 for renal tubule receptors and play a role in regulating overall FGF23 activity. The production of FGF23 is regulated by a variety of factors, including calcium and phosphate levels, 1,25 dihydroxyvitamin D, parathyroid hormone, and iron deficiency. Elevated FGF23 levels are associated with chronic kidney disease as well as cardiovascular disease. PMID: 24269946 Source: Regenstrief LOINC

LP62864-1 FISH
FISH (fluorescence in situ hybridization) is a cytogenetic technique used to detect and localize the presence or absence of specific DNA sequences on chromosomes. FISH uses fluorescent probes that bind to only those parts of the chromosome with which they show a high degree of sequence similarity. Fluorescence microscopy can be used to find out where the fluorescent probe bound to the chromosomes. FISH is often used for finding specific features in DNA for use in genetic counseling, medicine, and species identification. FISH can also be used to detect and localize specific mRNAs within tissue samples. In this context, it can help define the spatial-temporal patterns of gene expression within cells and tissues. Copyright Text is available under the Creative Commons Attribution/Share-Alike License. See http://creativecommons.org/licenses/by-sa/3.0/ for details. Source: Wikipedia, FISH

LOINC Names Get Info

Fully-Specified Name: Fibroblast growth factor 23:PrThr:Pt:Tiss:Ord:FISH
Long Common Name: Fibroblast growth factor 23 [Presence] in Tissue by FISH
Short Name: FGF-23 tiss Ql FISH
Display Name: Fibroblast growth factor 23 FISH Ql (Tiss)
Consumer Name Alpha Get Info: Fibroblast growth factor 23, Tissue

Part Model Get Info

Component
Fibroblast growth factor 23
LP40488-6
- Analyte
  Fibroblast growth factor 23
  LP40488-6
  - Component Numerator
    Fibroblast growth factor 23
    LP40488-6
    - Component Numerator Core
      Fibroblast growth factor 23
      LP40488-6
    - Component Numerator Core Suffix
      NULL
  - Component Denominator
    NULL
    - Component Denominator Core
      NULL
    - Component Denominator Core Suffix
      NULL
- Challenge
  NULL
- Adjustment
  NULL
- Count
  NULL
Property
PrThr
LP217195-9
Time
Pt
LP6960-1
- Time Core
  Pt
  LP6960-1
- Time Modifier
  NULL
System
Tiss
LP7641-6
- System Core
  Tiss
  LP7641-6
- Super System
  NULL
Scale
Ord
LP7751-3
Method
FISH
LP62864-1

Basic Attributes

Class: CHEM
Type: Laboratory
First Released: Version 2.77
Last Updated: Version 2.79 (MAJ)
Change Reason: Release 2.79: SYSTEM: Correction to revert to agreed upon representation;
Order vs. Observation: Both

Language Variants Get Info

Tag	Language	Translation
cs-CZ	Czech (Czechia)	Fibroblastový růstový faktor 23:Přítomnost nebo práh:Časový bod:Tkáň:Ordinální:Fluorescenční in situ hybridizace (FISH)
el-GR	Greek (Greece)	Αυξητικός παράγοντας ινοβλαστών 23:PrThr:Pt:Ιστός:Ord:Φθορίζουσα υβριδοποίηση in situ Synonyms: CHEM Ord PrThr Pt Αυξητικός παράγοντας ινοβλαστών 23 Ιστός Φθορίζουσα υβριδοποίηση in situ
es-ES	Spanish (Spain)	Factor de crecimiento fibroblástico 23:PrThr:Punto temporal:Tejido:Ord:Hibridación in situ fluoresente (FISH)
et-EE	Estonian (Estonia)	Fibroblastide kasvufaktor 23:PrThr:Pt:Tis:Ord:FISH Synonyms: Järgarvuline Juhuslik Kude
fr-FR	French (France)	FGF-23:Présence/Seuil:Ponctuel:Tissu:Qualitatif:FISH
fr-BE	French (Belgium)	Facteur de croissance fibroblaste 23:PrThr:Temps ponctuel:Tissu:Ordinal:Hybridation fluorescente in situ Synonyms: FISH
fr-CA	French (Canada)	Facteur de croissance fibroblaste 23:Présence-Seuil:Temps ponctuel:Tissu:Ordinal:Hybridation fluorescente in situ
it-IT	Italian (Italy)	Fibroblasto 23, fattore di crescita:PrThr:Pt:Tessuto:Ord:FISH Synonyms: Chimica Fattore di crescita del fibroblasto 23 Ibridazione in situ fluorescente (FISH) Presenza o Soglia Punto nel tempo (episodio) Tessuto & Strisci
nl-NL	Dutch (Netherlands)	fibroblast groeifactor 23:aanwezigheid:moment:weefsel en uitstrijkjes:ordinaal:FISH
pl-PL	Polish (Poland)	Czynnik wzrostu fibroblastów 23:granica wykrywalności:punkt w czasie:tkanka i rozmazy:uporządkowany:FISH Synonyms: FGF-23 fluorescencyjna hybrydyzacja in situ
tr-TR	Turkish (Turkey)	Fibroblast büyüme faktörü 23:MevcEşik:Zmlı:Doku:Srl:FISH Synonyms: Mevcut
zh-CN	Chinese (China)	成纤维细胞生长因子 23:存在情况或阈值:时间点:组织与涂片:序数型:FISH Synonyms: FGF 23;FGF23;FGF-23;Fibroblast GF 23;伴有高磷血症的家族性肿瘤性普遍性钙质沉着;伴有高磷血症的家族性肿瘤性石未沉着症;伴有高磷血症的家族性肿瘤性钙质沉着;伴有高磷血症的家族性肿瘤性钙质沉着症;伴有高磷酸盐血症的家族性肿瘤性普遍性钙质沉着;伴有高磷酸盐血症的家族性肿瘤性石未沉着症;伴有高磷酸盐血症的家族性肿瘤性钙质沉着;伴有高磷酸盐血症的家族性肿瘤性钙质沉着症;常染色体显性低磷佝偻病;常染色体显性低磷软骨病;常染色体显性低磷酸盐性佝偻症;常染色体显性低磷酸盐性软骨病;纤维 Fluorescent in situ hybridization;荧光原位杂交依次型;分类顺序型;定性的;序数型（或称等级型）;性质上的;有序型;有序性分类应答;有序性分类结果;秩次型;等级型;筛查;顺序型化学;化学检验项目;化学检验项目类;化学类;化学试验;非刺激耐受型化学检验项目;非刺激耐受型化学检验项目类;非刺激耐受型化学试验;非刺激耐受型化学试验类因素存在情况;存在;存在与否;是否存在;阈值;界值;界限;阀值;临界值;存在情况（存在、存在与否、是否存在）或阈值（界值、界限、阀值、临界值）时刻;随机;随意;瞬间未作说明的组织;组织;组织 & 涂片系数纤维原细胞生长因子纤维母细胞生长因子

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LOINC Copyright

Copyright © Regenstrief Institute, Inc. All Rights Reserved. To the extent included herein, the LOINC table and LOINC codes are copyright © Regenstrief Institute, Inc. and the Logical Observation Identifiers Names and Codes (LOINC) Committee. See https://loinc.org/license for the full LOINC copyright and license.