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Part Description

LP437609-3   V gene rearrangement
The gene rearrangement that combines two or three gene segments to form a complete V-region exon generates diversity in two ways. First, there are multiple different copies of each type of gene segment, and different combinations of gene segments can be used in different rearrangement events. This combinatorial diversity is responsible for a substantial part of the diversity of the heavy- and light-chain V regions. Second, junctional diversity is introduced at the joints between the different gene segments as a result of addition and subtraction of nucleotides by the recombination process. A third source of diversity is also combinatorial, arising from the many possible different combinations of heavy- and light-chain V regions that pair to form the antigen-binding site in the immunoglobulin molecule. The two means of generating combinatorial diversity alone could give rise, in theory, to approximately 3.5 × 106 different antibody molecules. Source: NCBI PubMed,

LOINC Names Get Info

Fully-Specified Name
V gene rearrangement:Prid:Pt:XXX:Nom:Molgen
Long Common Name
V gene rearrangement [Identifier] in Specimen by Molecular genetics method Nominal
Short Name
V-region genes Spec
Display Name
V gene rearrangement Molgen Nom (Specimen)
Consumer Name Alpha Get Info
V gene rearrangement, Specimen

Part Model Get Info

  • Component
    V gene rearrangement
    LP437609-3
    • Analyte
      V gene rearrangement
      LP437609-3
      • Component Numerator
        V gene rearrangement
        LP437609-3
        • Component Numerator Core
          V gene rearrangement
          LP437609-3
        • Component Numerator Core Suffix
          NULL
           
      • Component Denominator
        NULL
         
        • Component Denominator Core
          NULL
           
        • Component Denominator Core Suffix
          NULL
           
    • Challenge
      NULL
       
    • Adjustment
      NULL
       
    • Count
      NULL
       
  • Property
    Prid
    LP6850-4
  • Time
    Pt
    LP6960-1
  • System
    XXX
    LP7735-6
    • System Core
      XXX
      LP7735-6
    • Super System
      NULL
       
  • Scale
    Nom
    LP7750-5
  • Method
    Molgen
    LP6404-0

Example Answer List: LL6551-7

AnswerCodeScoreAnswer ID
IGHV4-34*02LA34026-7
IGHV4-39*01LA34027-5
IGHV3-48*02LA34028-3
IGHV1-58*02LA34029-1
IGHV4-59*01LA34030-9
IGHV4-59*08LA34031-7
IGHV1-69*01LA34032-5
IGHV1-2*02LA34033-3
IGHV1-2*04LA34034-1
IGHV1-3*01LA34035-8
IGHV2-5*05LA34036-6
IGHV2-5*10LA34037-4
IGHV3-7*03LA34038-2
IGHV3-11*05LA34039-0
IGHV3-13*01LA34040-8
IGHV3-15*06LA34041-6
IGHV3-23*01LA34042-4
IGHV3-30*14LA34043-2
IGHV3-30*18LA34044-0

Basic Attributes

Class
MOLPATH.REARRANGE
Type
Laboratory
First Released
Version 2.77
Last Updated
Version 2.77 (ADD)
Order vs. Observation
Observation

Language Variants Get Info

TagLanguageTranslation
cs-CZCzech (Czechia)Gen V přestavba:Přítomnost nebo identita:Časový bod:XXX:Nominální:Molekulární genetika
el-GRGreek (Greece)Αναδιατάξεις γονιδίων V:Prid:Pt:XXX:Nom:Μοριακή γενετική
Synonyms: MOLPATH MOLPATH.REARRANGE Nom Prid Pt V XXX Αναδιατάξεις γονιδίων V Γονίδιο Μοριακή γενετική
es-ESSpanish (Spain)Reordenamiento de gen V:Presencia o identidad:Punto temporal:XXX:Nom:Genética molecular
fr-FRFrench (France)V gène réarrangement:Identification:Ponctuel:Milieux divers:Résultat nominal:Biologie moléculaire
it-ITItalian (Italy)Riarrangiamenti genici V:Prid:Pt:XXX:Nom:Molgen
Synonyms: Genetica molecolare Patologia molecolare Presenza o Identità Punto nel tempo (episodio) Riarrangiamento genico
nl-NLDutch (Netherlands)V-genherschikking:identificator:moment:XXX:nominaal:moleculair genetisch onderzoek
Synonyms: molgen
pl-PLPolish (Poland)Rearanżacja genu V:obecność lub identyfikacja:punkt w czasie:XXX:skala nominalna:genetyka molekularna
Synonyms: diagnostyka molekularna Rearanżacja genu regionu V wynik kategorialny
zh-CNChinese (China)V 基因重排:存在与否或特征标识:时间点:XXX:名义型:分子遗传学类实验室方法
Synonyms: V 型 V 基因重排（重组） 不明的;其他;将在相应消息内其他部分之中加以详细说明;未作详细说明的;未作说明的;未做说明的标本;未加规定的;未加说明的标本;杂项 分子病理学.基因重排;分子病理学.重排;分子病理学试验.基因重排;分子病理学试验.重排;分子病理学试验类.重排;基因重排;重排 分子病理学;分子病理学试验 分子遗传学;分子遗传学方法;分子遗传学类方法;分子遗传学类检验方法;包括 RFL、PCR 及其他方法在内，用于在分子基础上检测遗传属性的方法的大类;聚合酶链反应;聚合酶链式反应 分类型应答;分类型结果;名义性;名称型;名词型;名词性;标称性;没有自然次序的名义型或分类型应答 存在;存在与否;特征标识;身份;身份标识 时刻;随机;随意;瞬间 遗传基因;遗传因子;吉恩;生物基因

LOINC Terminology Service (API) using HL7® FHIR® Get Info

CodeSystem lookup
https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=104269-6