LOINC
Version 2.69

10474-5Collagen type 4 Ag [Presence] in Tissue by Immune stainActive

Part Description

LP14655-2   Collagen type 4
Type-IV collagen is a type of collagen found primarily in the basal lamina. The type IV collagen C4 domain at the C-terminus is not removed in post-translational processing, and the fibers link head-to-head, rather than in parallel. Also, type-IV lacks the regular glycine in every third residue necessary for the tight, collagen helix. This makes the overall arrangement more sloppy with kinks. These two features cause the collagen to form in a sheet, the form of the basal lamina.

The alpha 3 protein constituent of type-IV collagen is thought to be the antigen implicated in Goodpasture's syndrome, wherein the immune system attacks the basement membranes of the glomeruli and the alveoli.

Mutations to the genes coding for type-IV collagen lead to Alport syndrome. Copyright Text is available under the Creative Commons Attribution/Share-Alike License. See http://creativecommons.org/licenses/by-sa/3.0/ for details. Source: Wikipedia, Type-IV collagen

Fully-Specified Name

Component
Collagen type 4 Ag
Property
PrThr
Time
Pt
System
Tiss
Scale
Ord
Method
Immune stain

Additional Names

Short Name
Collagen4 Ag Tiss Ql ImStn
Display Name
Collagen type 4 Ag Immune stain Ql (Tiss)
Consumer Name Alpha
Collagen Type 4 antigen, Tissue

Basic Attributes

Class
PATH
Type
Laboratory
First Released
Version 1.0i
Last Updated
Version 2.56
Change Reason
The PrThr property is used for LOINC terms whose results are reported using an ordered categorical scale, regardless of whether or not an internal threshold was used to make that determination. This change was approved by the Laboratory LOINC Committee in June 2016.
Order vs. Observation
Both

Language Variants Get Info

zh-CNChinese (China)
胶原 4 型 抗原:存在情况或阈值:时间点:组织与涂片:序数型:免疫染色法
nl-NLDutch (Netherlands)
collageen type 4 Ag:aanwezigheid:moment:weefsel en uitstrijkjes:ordinaal:immunokleuring
et-EEEstonian (Estonia)
Kollageeni tüüp 4 antigeen:PrThr:Pt:Tis:Ord:Immuunvärv
fr-BEFrench (Belgium)
Collagène de type IV Ag:PrThr:Temps ponctuel:Tissu:Ordinal:Coloration immunologique
fr-CAFrench (Canada)
Collagène de type IV , Ag:Présence-Seuil:Temps ponctuel:Tissu:Ordinal:Coloration immunologique
fr-FRFrench (France)
Collagène type 4 antigène:Présence/Seuil:Ponctuel:Tissu:Qualitatif:Coloration immune
it-ITItalian (Italy)
Collagene tipo 4 , Ag:PrThr:Pt:Tessuto:Ord:Colorazione immunologica
ko-KRKorean (Korea, Republic of)
아교질 4 형 항원:임의농도:검사시점:조직:순위척도:면역염색
pt-BRPortuguese (Brazil)
Colágeno tipo 4 Ag:ACnc:Pt:Tecido:Ord:Imunocoloração
ru-RURussian (Russian Federation)
Коллаген тип 4 Аг:PrThr:ТчкВрм:Тк:Пор:Иммуногистохимическая окраска
es-ARSpanish (Argentina)
antígeno de colágeno tipo 4:concentración arbitraria:punto en el tiempo:tejido, no especificado:ordinal:tinción inmunológica
es-ESSpanish (Spain)
Colageno tipo 4 Antígeno:PrThr:Punto temporal:Tejido:Ord:Tinción de inmunohistoquímica
tr-TRTurkish (Turkey)
Kollajen tip 4 Ag:MevcEşik:Zmlı:Doku:Srl:İmmün boyama

LOINC FHIR® API Example - CodeSystem Request Get Info

https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=10474-5