10474-5Collagen type 4 Ag [Presence] in Tissue by Immune stainActive
Part Description
LP14655-2 Collagen type 4
Type-IV collagen is a type of collagen found primarily in the basal lamina. The type IV collagen C4 domain at the C-terminus is not removed in post-translational processing, and the fibers link head-to-head, rather than in parallel. Also, type-IV lacks the regular glycine in every third residue necessary for the tight, collagen helix. This makes the overall arrangement more sloppy with kinks. These two features cause the collagen to form in a sheet, the form of the basal lamina.
The alpha 3 protein constituent of type-IV collagen is thought to be the antigen implicated in Goodpasture's syndrome, wherein the immune system attacks the basement membranes of the glomeruli and the alveoli.
Mutations to the genes coding for type-IV collagen lead to Alport syndrome.
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Source: Wikipedia, Type-IV collagen
Fully-Specified Name
- Component
- Collagen type 4 Ag
- Property
- PrThr
- Time
- Pt
- System
- Tiss
- Scale
- Ord
- Method
- Immune stain
Additional Names
- Short Name
- Collagen4 Ag Tiss Ql ImStn
- Display Name
- Collagen type 4 Ag Immune stain Ql (Tiss)
- Consumer Name Alpha
- Collagen type 4 antigen, Tissue
Basic Attributes
- Class
- PATH
- Type
- Laboratory
- First Released
- Version 1.0i
- Last Updated
- Version 2.56
- Change Reason
- The PrThr property is used for LOINC terms whose results are reported using an ordered categorical scale, regardless of whether or not an internal threshold was used to make that determination. This change was approved by the Laboratory LOINC Committee in June 2016.
- Order vs. Observation
- Both
Language Variants Get Info
- zh-CNChinese (China)
- 胶原 4 型 抗原:
存在情况或阈值: 时间点: 组织与涂片: 序数型: 免疫染色法 - nl-NLDutch (Netherlands)
- collageen type 4 Ag:
aanwezigheid: moment: weefsel en uitstrijkjes: ordinaal: immunokleuring - et-EEEstonian (Estonia)
- Kollageeni tüüp 4 antigeen:
PrThr: Pt: Tis: Ord: Immuunvärv - fr-BEFrench (Belgium)
- Collagène de type IV Ag:
PrThr: Temps ponctuel: Tissu: Ordinal: Coloration immunologique - fr-CAFrench (Canada)
- Collagène de type IV , Ag:
Présence-Seuil: Temps ponctuel: Tissu: Ordinal: Coloration immunologique - fr-FRFrench (France)
- Collagène type 4 antigène:
Présence/Seuil: Ponctuel: Tissu: Qualitatif: Coloration immune - it-ITItalian (Italy)
- Collagene tipo 4 , Ag:
PrThr: Pt: Tessuto: Ord: Colorazione immunologica - ko-KRKorean (Korea, Republic of)
- 아교질 4 형 항원:
임의농도: 검사시점: 조직: 순위척도: 면역염색 - pt-BRPortuguese (Brazil)
- Colágeno tipo 4 Ag:
ACnc: Pt: Tecido: Ord: Imunocoloração - ru-RURussian (Russian Federation)
- Коллаген тип 4 Аг:
PrThr: ТчкВрм: Тк: Пор: Иммуногистохимическая окраска - es-ARSpanish (Argentina)
- antígeno de colágeno tipo 4:
concentración arbitraria: punto en el tiempo: tejido, no especificado: ordinal: tinción inmunológica - es-MXSpanish (Mexico)
- Colágeno tipo 4 Ag:
Presencia o umbral: Punto temporal: Tejido y frotis: Ordinal: Mancha inmune - es-ESSpanish (Spain)
- Colageno tipo 4 Antígeno:
PrThr: Punto temporal: Tejido: Ord: Tinción de inmunohistoquímica - tr-TRTurkish (Turkey)
- Kollajen tip 4 Ag:
MevcEşik: Zmlı: Doku: Srl: İmmün boyama
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