104772-9

Salmonella sp serotype [Identifier] in Isolate by Sequencing

Active

Part Descriptions

LP150045-5   Sequencing
Sequencing is a method used to determine the sequence of individual genes, larger genetic regions (i.e. clusters of genes or operons), full chromosomes or entire genomes. Historically, most sequencing has been performed using the chain termination method developed by Frederick Sanger in 1977. PMID: 271968 Sequencing technologies have improved dramatically, making them cheaper, faster, and more accurate. Next-generation sequencing (NGS), also known as high-throughput sequencing, deep sequencing, and second-generation sequencing, is a type of technology that uses parallel sequencing of multiple small fragments of DNA to determine sequence. This "high-throughput" technology has increased the speed and amount of DNA sequenced at a significantly reduced cost. PMID: 18576944 Several NGS platforms (ie, sequencing instruments and associated reagents) have been developed. Third-generation sequencing is another methodology currently under development that uses parallel sequencing similar to NGS. In contrast to NGS, third-generation sequencing uses single DNA molecules rather than amplified DNA as a template. PMID: 20858600 Source: Regenstrief LOINC

LP16750-9   Salmonella sp
Salmonella are gram-negative, flagellated, facultative intracellular, anaerobic bacilli with O, H and Vi surface antigens. Once ingested, Salmonella survives the gastric acid barrier and penetrates the epithelial cells of the small and large intestines. The invasion of the epithelial cells stimulates the release of cytokines and a subsequent inflammatory response leading to diarrhea and possible ulceration of the mucosa.[NCBI Books: 8435] Antibodies to Salmonella are the body's defense when the bacteria is outside of its host cell which occurs at the initial infection and when the bacillus moves from cell to cell. There is a 10 minute window of opportunity when the Salmonella bacillus leaves the macrophage to invade another. During that time, antibodies and complement work to eradicate the bacilli, but some of the extracellular bacilli will evade attack and enter another host cell. Studies have shown that vaccines play an important role in the fight against typhoid fever. PMID: 25566248 There are two species of Salmonella: S. enterica and S. bongori. These species can be further subclassified into subspecies and serovars.

Veterinary Medicine:
Salmonella infection is most often caused by the serovars Salmonella choleraesuis, and Salmonella typhimurium and less often by Salmonella derby. Infected pigs can be asymptomatic and become carriers of S. choleraesius. Typically, the bacteria survive in the mesenteric lymph nodes that drain into the intestines, and are not shed in the feces unless the pig is under stress. The carrier state lasts for weeks to months and is self-limiting. Severe infection with S. choleraesius can be serious starting out as septicemia and progressing to pneumonia and enteritis. The infection can spread to various tissues including to the central nervous system leading to meningitis and to the joints where it manifests as arthritis. Severe infections with S. choleraesius occurs at any age, but most often in pigs 12-14 weeks of age.http://www.thepigsite.com/pighealth/article/357/salmonellosis/ Source: Regenstrief LOINC

LOINC Names Get Info

Fully-Specified Name

Salmonella sp serotype:ID:Pt:Isolate:Nom:Sequencing

Long Common Name

Salmonella sp serotype [Identifier] in Isolate by Sequencing

Short Name

Salmonella Sertyp Islt Seq

Display Name

Salmonella sp serotype Sequencing Nom (Isol) [ID]

Consumer Name Alpha Get Info

Salmonella sp serotype

Part Model Get Info

• Component

  Salmonella sp serotype
  LP174086-1

  • Analyte

    Salmonella sp serotype
    LP174086-1

    • Component Numerator

      Salmonella sp serotype
      LP174086-1

      • Component Numerator Core

        Salmonella sp
        LP16750-9

      • Component Numerator Core Suffix

        serotype
        LP29274-5

    • Component Denominator

      NULL
       

      • Component Denominator Core

        NULL
         

      • Component Denominator Core Suffix

        NULL
         

  • Challenge

    NULL
     

  • Adjustment

    NULL
     

  • Count

    NULL
     

• Property

  ID
  LP6818-1

• Time

  Pt
  LP6960-1

  • Time Core

    Pt
    LP6960-1

  • Time Modifier

    NULL
     

• System

  Isolate
  LP7370-2

  • System Core

    Isolate
    LP7370-2

  • Super System

    NULL
     

• Scale

  Nom
  LP7750-5

• Method

  Sequencing
  LP150045-5

Basic Attributes

Class

MICRO

Type

Laboratory

First Released

Version 2.78

Last Updated

Version 2.78 (ADD)

Order vs. Observation

Both

Language Variants Get Info

Related Names

• high-throughput sequencing
• HTS
• Ident
• Identifier
• Islt
• Isol
• Microbiology
• Next generation sequencing
• NGS
• Nominal
• Point in time
• Random
• Sal
• Salmonel
• Sertyp
• species
• spp

LOINC Terminology Service (API) using HL7^® FHIR^® Get Info

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CodeSystem lookup

https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=104772-9

LOINC Copyright

Copyright © Regenstrief Institute, Inc. All Rights Reserved. To the extent included herein, the LOINC table and LOINC codes are copyright © Regenstrief Institute, Inc. and the Logical Observation Identifiers Names and Codes (LOINC) Committee. See https://loinc.org/license for the full LOINC copyright and license.