Version 2.80

Part Description

LP220403-2   MDA5
MDA5, more formally known as interferon-induced helicase C domain-containing protein 1, is an immune receptor for viral nucleic acids and plays a major role in activating antiviral responses, including the induction of type I interferons and proinflammatory cytokines. Anti-MDA5 autoantibodies, also known as anti-CADM-140, are associated with autoimmune disorders including dermatomyositis and interstitial lung disease. [UniProt: Q9BYX4] Anti-MDA5 autoantibodies are also found in a subset of patients with juvenile dermatomyositis (JDM) who have polyarthritis and ulcerative skin disease but milder muscle disease. Anti-MDA5 assays may be useful during the work-up of patients with inflammatory disorders and may help guide treatment. PMID: 24989778 Source: Regenstrief LOINC , PMID: 24989778

Fully-Specified Name

Component
MDA5 Ab
Property
ACnc
Time
Pt
System
Ser
Scale
Qn
Method

Additional Names

Long Common Name
MDA5 Ab [Units/volume] in Serum
Short Name
MDA5 Ab Ser-aCnc
Display Name
MDA5 Ab Qn (S)
Consumer Name Alpha Get Info
MDA5 antibody, Blood

Basic Attributes

Class
SERO
Type
Laboratory
First Released
Version 2.78
Last Updated
Version 2.78 (ADD)
Order vs. Observation
Both

Member of these Groups Get Info

LOINC Group Group Name
LG51600-1 MDA5 Ab|ACnc|Pt|ANYBldSerPl

Language Variants Get Info

Tag Language Translation
el-GR Greek (Greece) MDA5 Αντίσωμα:ACnc:Pt:Ορός:Qn:
Synonyms: ACnc
es-ES Spanish (Spain) MDA5 Anticuerpos:Concentración arbitraria:Punto temporal:Suero:Qn:
Synonyms: Cuantitativo
fr-FR French (France) MDA5 anticorps:Arbitraire/Volume:Ponctuel:Sérum:Numérique:
it-IT Italian (Italy) MDA5 Ab:ACnc:Pt:Siero:Qn:
Synonyms: anticorpo Concentrazione Arbitraria Punto nel tempo (episodio) Siero Sierologia (anticorpi e la maggior parte degli ant
nl-NL Dutch (Netherlands) MDA5 As:eenheid/volume:moment:serum:kwantitatief:
Synonyms: antistof; antilichaam
zh-CN Chinese (China) MDA5 抗体:任意型浓度:时间点:血清:定量型:
Synonyms: Ab;自身抗体 任意型浓度(单位体积);任意浓度;单位体积的任意单位数;人工型浓度 可用数量表示的;定量性;数值型;数量型;连续数值型标尺 干扰素诱导型解旋酶 C 结构域包含型蛋白 1;interferon-induced helicase C domain-containing protein 1 时刻;随机;随意;瞬间 血清;血清学;血清学检验项目;血清学检验项目 (非微生物学);血清学检验项目（非微生物学）;血清学检验项目类;血清学检验项目类 (非微生物学);血清学类;血清学类检验项目;血清学类检验项目 (非微生物学);血清学类试验;血清学类试验 (非微生物学);血清学试验;血清学试验 (非微生物学);血清学试验（非微生物学）;血清学试验类 (非微生物学);血清类

Example Units

Unit Source
U/mL Example UCUM Units

LOINC Terminology Service (API) using HL7® FHIR® Get Info

CodeSystem lookup
https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=105529-2