Version 2.80

Part Description

LP150045-5   Sequencing
Sequencing is a method used to determine the sequence of individual genes, larger genetic regions (i.e. clusters of genes or operons), full chromosomes or entire genomes. Historically, most sequencing has been performed using the chain termination method developed by Frederick Sanger in 1977. PMID: 271968 Sequencing technologies have improved dramatically, making them cheaper, faster, and more accurate. Next-generation sequencing (NGS), also known as high-throughput sequencing, deep sequencing, and second-generation sequencing, is a type of technology that uses parallel sequencing of multiple small fragments of DNA to determine sequence. This "high-throughput" technology has increased the speed and amount of DNA sequenced at a significantly reduced cost. PMID: 18576944 Several NGS platforms (ie, sequencing instruments and associated reagents) have been developed. Third-generation sequencing is another methodology currently under development that uses parallel sequencing similar to NGS. In contrast to NGS, third-generation sequencing uses single DNA molecules rather than amplified DNA as a template. PMID: 20858600 Source: Regenstrief LOINC

Fully-Specified Name

Component
Lung cancer screening
Property
PrThr
Time
Pt
System
Plas.cfDNA
Scale
Ord
Method
Sequencing

Additional Names

Long Common Name
Lung cancer screening [Presence] based on Plasma cell-free DNA by Sequencing
Short Name
Lung ca screening Plas.cfDNA Ql
Display Name
Lung cancer screening Sequencing Ql (cfDNA)
Consumer Name Alpha Get Info
Fetal Lung cancer screening

Example Answer List: LL6864-4

Source: Abbott Laboratories
Answer Code Score Answer ID
Elevated LA32146-5
Not elevated LA32147-3
No results reported LA34460-8

Basic Attributes

Class
MOLPATH
Type
Laboratory
First Released
Version 2.78
Last Updated
Version 2.78 (ADD)
Order vs. Observation
Both

Language Variants Get Info

Tag Language Translation
es-ES Spanish (Spain) Cribado de detección del cáncer de pulmón:PrThr:Punto temporal:ADN en plasma libre de células:Ord:Secuenciación
fr-FR French (France) Dépistage du cancer du poumon:Présence/Seuil:Ponctuel:Plasma avec ADN libre circulant:Qualitatif:Séquençage
it-IT Italian (Italy) Screening cancro al polmone:PrThr:Pt:Plasma.DNA libero circolante:Ord:Sequenziamento
Synonyms: DNA libero circolante nel plasma Patologia molecolare Plasma Presenza o Soglia Punto nel tempo (episodio) Screening per il cancro
nl-NL Dutch (Netherlands) screenen op longkanker:aanwezigheid:moment:plasma.celvrij DNA:ordinaal:sequencing
Synonyms: circulerend DNA
zh-CN Chinese (China) 肺癌筛查:存在情况或阈值:时间点:血浆.cfDNA:序数型:序列测定
Synonyms: Asympt SCN 依次型;分类顺序型;定性的;序数型（或称等级型）;性质上的;有序型;有序性分类应答;有序性分类结果;秩次型;等级型;筛查;顺序型 分子病理学;分子病理学试验 存在情况;存在;存在与否;是否存在;阈值;界值;界限;阀值;临界值;存在情况（存在、存在与否、是否存在）或阈值（界值、界限、阀值、临界值） 序列分析;测序 无症状 无症状（Asymptomatic，Asympt） 无症状的 无症状筛查 时刻;随机;随意;瞬间 普查 普查试验 癌 癌症过筛 筛分 筛分试验 筛查（Screening，SCN） 筛查试验 筛选 筛选试验 血浆循环 cfDNA;血浆循环 DNA;循环游离核酸;血浆游离 DNA;血浆无细胞 DNA;Free circulating/Cell-free DNA;Free circulating DNA

LOINC Terminology Service (API) using HL7® FHIR® Get Info

CodeSystem lookup
https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=105603-5