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Term Description

This term represents the assay which detects antibodies against the lethal factor component of the anthrax toxin produced by Bacillus anthracis. This assay is crucial for understanding immune responses to anthrax exposure, aiding in diagnosis of anthrax infection, and evaluating vaccine efficacy. It can be performed on serum and venous whole blood samples (using dipotassium EDTA, sodium citrate, or sodium heparin as anticoagulants) from individuals with signs and symptoms consistent with inhalation anthrax and a likelihood of exposure. PMID: 30776143

Part Description

LP444041-0   Bacillus anthracis lethal factor
Bacillus anthracis lethal factor is one of the three components of the anthrax toxin produced by the bacterium Bacillus anthracis, which causes anthrax. This protein acts as a zinc-dependent metalloprotease that, when combined with protective antigen (PA) and entering host cells, disrupts cellular signaling by inactivating mitogen-activated protein kinases (MAPKs), leading to cell death, particularly in immune cells like macrophages, and contributing to the overall pathogenic effects of anthrax infection. Source: LOINC

LOINC Names Get Info

Fully-Specified Name
Bacillus anthracis lethal factor Ab:PrThr:Pt:Ser:Ord:IA
Long Common Name
Bacillus anthracis lethal factor Ab [Presence] in Serum by Immunoassay
Short Name
B. anthracis LF Ab Ser Ql IA
Display Name
Bacillus anthracis lethal factor Ab IA Ql (S)
Consumer Name Alpha Get Info
Bacillus anthracis lethal factor antibody, Blood

Part Model Get Info

  • Component
    Bacillus anthracis lethal factor Ab
    LP444042-8
    • Analyte
      Bacillus anthracis lethal factor Ab
      LP444042-8
      • Component Numerator
        Bacillus anthracis lethal factor Ab
        LP444042-8
        • Component Numerator Core
          Bacillus anthracis lethal factor
          LP444041-0
        • Component Numerator Core Suffix
          Ab
          LP20667-9
      • Component Denominator
        NULL
         
        • Component Denominator Core
          NULL
           
        • Component Denominator Core Suffix
          NULL
           
    • Challenge
      NULL
       
    • Adjustment
      NULL
       
    • Count
      NULL
       
  • Property
    PrThr
    LP217195-9
  • Time
    Pt
    LP6960-1
  • System
    Ser
    LP7567-3
    • System Core
      Ser
      LP7567-3
    • Super System
      NULL
       
  • Scale
    Ord
    LP7751-3
  • Method
    IA
    LP217197-5

Example Answer List: LL6976-6

AnswerCodeScoreAnswer ID
PositiveCopyright http://snomed.info/sct ID:10828004 Positive (qualifier value)LA6576-8
NegativeCopyright http://snomed.info/sct ID:260385009 Negative (qualifier value)LA6577-6

Basic Attributes

Class
MICRO
Type
Laboratory
First Released
Version 2.79
Last Updated
Version 2.79 (ADD)
Order vs. Observation
Observation

Member of these Groups Get Info

LOINC GroupGroup Name
LG41626-9Bacillus anthracis

Language Variants Get Info

TagLanguageTranslation
de-DEGerman (Germany)Bacillus anthracis Letaler Faktor Ak:Nachweis oder Schwellenwert:Zeitpunkt:Serum:Ordinal:Immunoassay
fr-FRFrench (France)Bacillus anthracis facteur létal Ac:Présence/Seuil:Ponctuel:Sérum:Qualitatif:Immunoanalyse
it-ITItalian (Italy)Fattore letale di Bacillus anthracis Ab:PrThr:Pt:Siero:Ord:IA
Synonyms: anticorpo Fattore letale (LF) di Bacillus anthracis Immunoassay Microbiologia Presenza o Soglia Punto nel tempo (episodio) Siero
pl-PLPolish (Poland)Czynnik letalny Bacillus anthracis Ab:granica wykrywalności:punkt w czasie:surowica:uporządkowany:metoda immunologiczna
Synonyms: Laseczka wąglika Toksyna LF Bacillus anthracis;czynnik letalny laseczki wąglika;toksyna LF laseczki wąglika
zh-CNChinese (China)炭疽芽孢杆菌致死因子 抗体:存在情况或阈值:时间点:血清:序数型:免疫测定法
Synonyms: Ab;自身抗体 依次型;分类顺序型;定性的;序数型（或称等级型）;性质上的;有序型;有序性分类应答;有序性分类结果;秩次型;等级型;筛查;顺序型 免疫测定;免疫分析法;免疫检定法;免疫检定;免疫试验;酶免疫测定法;酶免疫测定;酶免疫分析法;酶免疫检定法;酶免疫检定;酶免疫试验 吸入性炭疽;恶性炭疽;恶性痈;恶性脓;拾垃圾者病;炭疽;炭疽杆菌;炭疽热;炭疽病;肺炭疽;脾热 因素 存在情况;存在;存在与否;是否存在;阈值;界值;界限;阀值;临界值;存在情况（存在、存在与否、是否存在）或阈值（界值、界限、阀值、临界值） 微生物学;微生物学试验;微生物学试验（培养、DNA、抗原及抗体） 时刻;随机;随意;瞬间 炭疽杆菌致死因子;炭疽致死因子;炭疽毒素致死组分 系数

LOINC Terminology Service (API) using HL7® FHIR® Get Info

CodeSystem lookup
https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=106743-8