106774-3
24,25-dihydroxyvitamin D3+24,25-dihydroxyvitamin D2 [Moles/volume] in Serum or Plasma
Active
Part Description
LP417252-6 24r-Hydroxycalcidiol+24r-Hydroxyercalcidiol
24,25-dihydroxyvitamin D (24,25 DHD), also known as 24r-Hydroxycalcidiol, is an INactive metabolite produced by alternative hydroxylation of 25 hydroxyvitamin D (25HDN) by the CYP24A1 enzyme. The hydroxylation by CYP24A1 competes with hydroxylation to active form 1,25-dihydroxyvitamin D (1,25 DHD) by the CYP27B1 enzyme, and is an important process that prevents overproduction of 1,25 DHD and resulting vitamin D toxicity. Testing for an elevated ratio of 25HDN to 24,25 DHD can be used to reveal the likely presence of mutations in the CYP24A1 gene PMID: 22648296.
Source: Regenstrief LOINC
Fully-Specified Name
- Component
- 24r-Hydroxycalcidiol+24r-Hydroxyercalcidiol
- Property
- SCnc
- Time
- Pt
- System
- Ser/Plas
- Scale
- Qn
- Method
Additional Names
- Long Common Name
- 24,25-dihydroxyvitamin D3+24,25-dihydroxyvitamin D2 [Moles/volume] in Serum or Plasma
- Short Name
- 24,25(OH)2 VitD SerPl-sCnc
- Display Name
- 24,25-dihydroxyvitamin D3+24,25-dihydroxyvitamin D2 [Moles/Vol]
- Consumer Name Alpha Get Info
- 24,25-dihydroxyvitamin D3+24,25-dihydroxyvitamin D2, Blood
Basic Attributes
- Class
- CHEM
- Type
- Laboratory
- First Released
- Version 2.79
- Last Updated
- Version 2.79 (ADD)
- Order vs. Observation
- Both
Member of these Groups Get Info
LOINC Group | Group Name |
---|---|
LG51734-8 | 24r-Hydroxycalcidiol+24r-Hydroxyercalcidiol| |
Language Variants Get Info
Tag | Language | Translation |
---|---|---|
el-GR | Greek (Greece) | 24r-υδροξυκαλσιδιόλη+24r-υδροξυερκαλσιδιόλη: Synonyms: SCnc |
es-ES | Spanish (Spain) | 24,25-dihidroxivitamina D3 + 24,25-dihidroxivitamina D2: Synonyms: Cuantitativo |
it-IT | Italian (Italy) | 24r-Idrossicalcidiolo+24r-Idrossicalcidiolo: Synonyms: 24,25-Diidrossivitamina D3+24,25-diidrossivitamina D2 Chimica Concentrazione di Sostanza Plasma Punto nel tempo (episodio) Siero Siero o Plasma |
nl-NL | Dutch (Netherlands) | 24,25-dihydroxyvitamine D3 + 24,25-dihydroxyvitamine D2: Synonyms: calcidiol; |
zh-CN | Chinese (China) | 24r-羟基钙二醇+24r,25-羟基钙化醇: Synonyms: 24(R),25-二羟基维生素 D; |
Example Units
Unit | Source |
---|---|
nmol/L | Example UCUM Units |
LOINC Terminology Service (API) using HL7® FHIR® Get Info
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- CodeSystem lookup
- https:
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LOINC Copyright
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