107162-0

Lipoprotein a [Moles/volume] in DBS by Turbidimetry

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Term Description

This term represents an assay quantifying lipoprotein(a) (Lp(a)) levels in blood samples, including dried blood spots, by measuring the turbidity produced when specific antibodies bind to Lp(a) particles. This technique has demonstrated improved accuracy with the addition of L-proline, allowing for effective assessment of Lp(a) concentrations, which are critical for evaluating cardiovascular disease risk. PMID: 7634492}

Part Descriptions

LP14886-3 Lipoprotein (little a)
Increased levels of lipoprotein (a) are observed in patients with coronary artery disease, stroke, cerebrovascular and peripheral vascular disease and rarely in venous thrombosis. Substantial increases are observed in nephrotic syndrome and end-state renal disease. DecreasedlLipoprotein (a) levels may be seen in several rare disorders such as lecithin:cholesterol acyltranferase [LCAT] deficiency, lipoprotein lipase [LPL] deficiency, and liver disease). Levels in African Americans may be 2 to 3 times higher than in Caucasians and Asians whereas Native Americans and Mexican Americans have lower levels than in Caucasians and Asians. Information from Quest Diagnostics.

Lipoprotein (a) is an LDL cholesterol particle that is attached to a special protein called apo(a). In large part, a person's level of Lp(a) is genetically inherited. Elevated levels of Lp(a), higher than 20 mg/dL to 30 mg/dL in the blood are linked to a greated likelihood of atherosclerosis and heart attacks in both men and women. (The risk is even more significant if the Lp(a) cholesterol elevation is accompanied by high LDL/HDL ratios.) It accounts for only 15% of cholesterol so elevations can be missed in patients with normal cholesterols. Has 95% homology with plasminogen and possible interesting biologic relation to other phenomenon. Source: Regenstrief Institute

LP14886-3 Lipoprotein (little a)
Lipoprotein (a) is a modified form of LDL to which another glycoprotein, termed apolipoprotein (a), is covalently bound. It contributes to atherogenic risk by multiple mechanisms that include inhibition of fibrinolysis, increased cholesterol deposition in the arterial wall, and enhanced oxidation of LDL cholesterol. The evidence linking Lp(a) levels and the risk of coronary disease is strongest for middle aged white men. Higher Lp(a) levels have been consistently observed in white and Asian groups with vascular disease, but not in African Americans. Copyright Copyright © 2006 - 2008 ClinLab Navigator, LLC. Source: ClinLab Navigator, Apolipoprotein (a)

LOINC Names Get Info

Fully-Specified Name: Lipoprotein (little a):SCnc:Pt:Bld.dot:Qn:Turbidimetry
Long Common Name: Lipoprotein a [Moles/volume] in DBS by Turbidimetry
Short Name: LPa DBS-sCnc
Display Name: Lipoprotein a Turbidimetry (DBS) [Moles/Vol]
Consumer Name Alpha Get Info: Lipoprotein A, Dried blood spot

Part Model Get Info

Component
Lipoprotein (little a)
LP14886-3
- Analyte
  Lipoprotein (little a)
  LP14886-3
  - Component Numerator
    Lipoprotein (little a)
    LP14886-3
    - Component Numerator Core
      Lipoprotein (little a)
      LP14886-3
    - Component Numerator Core Suffix
      NULL
  - Component Denominator
    NULL
    - Component Denominator Core
      NULL
    - Component Denominator Core Suffix
      NULL
- Challenge
  NULL
- Adjustment
  NULL
- Count
  NULL
Property
SCnc
LP6860-3
Time
Pt
LP6960-1
- Time Core
  Pt
  LP6960-1
- Time Modifier
  NULL
System
Bld.dot
LP21304-8
- System Core
  Bld.dot
  LP21304-8
- Super System
  NULL
Scale
Qn
LP7753-9
Method
Turbidimetry
LP173457-5

Basic Attributes

Class: CHEM
Type: Laboratory
First Released: Version 2.79
Last Updated: Version 2.79 (ADD)
Order vs. Observation: Both

Language Variants Get Info

Tag	Language	Translation
el-GR	Greek (Greece)	Λιποπρωτεΐνη (πεζό a):SCnc:Pt:Bld.dot:Qn:Θολωσιμετρία Synonyms: A Bld.dot CHEM Pt Qn SCnc Αίμα Θολωσιμετρία Λιποπρωτεΐνη Λιποπρωτεΐνη (πεζό a)
es-ES	Spanish (Spain)	Lipoproteína a:Concentración de sustancia:Punto temporal:gota de sangre (papel de filtro):Qn:Turbidimetría Synonyms: Cuantitativo
fr-FR	French (France)	Lipoprotéine petit a:Moles/Volume:Ponctuel:Sang buvard:Numérique:Turbidimétrie
it-IT	Italian (Italy)	Lipoproteina (a minuscola):SCnc:Pt:Sangue.su carta da filtro:Qn:Turbidimetria Synonyms: Chimica Concentrazione di Sostanza Lipoproteina a Lipoproteine Punto nel tempo (episodio) Sangue Spot sangue secco
pl-PL	Polish (Poland)	Lipoproteina (a):stężenie molowe:punkt w czasie:sucha kropla krwi:ilościowy:Turbidymetria
zh-CN	Chinese (China)	脂蛋白 (a):物质的量浓度:时间点:全血.斑点:定量型:比浊法 Synonyms: A 型 Lp(a);LPa;脂蛋白 (little a);脂蛋白 a LP;成分 - 化学 - 脂蛋白;脂蛋白类克分子浓度;克分子浓度(单位体积);摩尔浓度;摩尔浓度(单位体积);物质的量浓度(单位体积) 全血斑点(滤纸);滤纸;血液.斑点;血液斑点(滤纸) 化学;化学检验项目;化学检验项目类;化学类;化学试验;非刺激耐受型化学检验项目;非刺激耐受型化学检验项目类;非刺激耐受型化学试验;非刺激耐受型化学试验类可用数量表示的;定量性;数值型;数量型;连续数值型标尺时刻;随机;随意;瞬间浊度测量法;浊度测定法;浊度法血;血液

Example Units

Unit	Source
nmol/L	Example UCUM Units

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LOINC Copyright

Copyright © Regenstrief Institute, Inc. All Rights Reserved. To the extent included herein, the LOINC table and LOINC codes are copyright © Regenstrief Institute, Inc. and the Logical Observation Identifiers Names and Codes (LOINC) Committee. See https://loinc.org/license for the full LOINC copyright and license.