107563-9

MDA5 Ab [Presence] in Serum or Plasma

Active

Part Description

LP220403-2 MDA5
MDA5, more formally known as interferon-induced helicase C domain-containing protein 1, is an immune receptor for viral nucleic acids and plays a major role in activating antiviral responses, including the induction of type I interferons and proinflammatory cytokines. Anti-MDA5 autoantibodies, also known as anti-CADM-140, are associated with autoimmune disorders including dermatomyositis and interstitial lung disease. [UniProt: Q9BYX4] Anti-MDA5 autoantibodies are also found in a subset of patients with juvenile dermatomyositis (JDM) who have polyarthritis and ulcerative skin disease but milder muscle disease. Anti-MDA5 assays may be useful during the work-up of patients with inflammatory disorders and may help guide treatment. PMID: 24989778 Source: Regenstrief LOINC, PMID: 24989778

LOINC Names Get Info

Fully-Specified Name: MDA5 Ab:PrThr:Pt:Ser/Plas:Ord:
Long Common Name: MDA5 Ab [Presence] in Serum or Plasma
Short Name: MDA5 Ab SerPl Ql
Display Name: MDA5 Ab Ql
Consumer Name Alpha Get Info: MDA5 antibody, Blood

Part Model Get Info

Component
MDA5 Ab
LP220404-0
- Analyte
  MDA5 Ab
  LP220404-0
  - Component Numerator
    MDA5 Ab
    LP220404-0
    - Component Numerator Core
      MDA5
      LP220403-2
    - Component Numerator Core Suffix
      Ab
      LP20667-9
  - Component Denominator
    NULL
    - Component Denominator Core
      NULL
    - Component Denominator Core Suffix
      NULL
- Challenge
  NULL
- Adjustment
  NULL
- Count
  NULL
Property
PrThr
LP217195-9
Time
Pt
LP6960-1
- Time Core
  Pt
  LP6960-1
- Time Modifier
  NULL
System
Ser/Plas
LP7576-4
- System Core
  Ser/Plas
  LP7576-4
- Super System
  NULL
Scale
Ord
LP7751-3
Method
NULL

Basic Attributes

Class: SERO
Type: Laboratory
First Released: Version 2.81
Last Updated: Version 2.81 (ADD)
Order vs. Observation: Both

Member of these Panels

LOINC	Long Common Name
107564-7	Myositis specific Ab panel - Serum or Plasma

Member of these Groups Get Info

LOINC Group	Group Name
LG51793-4	MDA5 Ab\|PrThr\|Pt\|ANYBldSerPl

Language Variants Get Info

Tag	Language	Translation
el-GR	Greek (Greece)	MDA5 Αντίσωμα:PrThr:Pt:Ορός/Πλάσμα:Ord: Synonyms: MDA5 Ord PrThr Pt SERO Αντίσωμα Ορός Ορός/Πλάσμα Πλάσμα
es-ES	Spanish (Spain)	MDA5 Anticuerpos:PrThr:Punto temporal:Suero o Plasma:Ord:
fr-FR	French (France)	MDA5 Ac:Présence/Seuil:Ponctuel:Sérum/Plasma:Qualitatif:
it-IT	Italian (Italy)	MDA5 Ab:PrThr:Pt:Siero/Plasma:Ord: Synonyms: anticorpo Plasma Presenza o Soglia Punto nel tempo (episodio) Siero Siero o Plasma Sierologia (anticorpi e la maggior parte degli ant
nl-NL	Dutch (Netherlands)	MDA5 As:aanwezigheid:moment:serum of plasma:ordinaal: Synonyms: antistof; antilichaam
zh-CN	Chinese (China)	MDA5 抗体:存在情况或阈值:时间点:血清/血浆:序数型: Synonyms: Ab;自身抗体依次型;分类顺序型;定性的;序数型（或称等级型）;性质上的;有序型;有序性分类应答;有序性分类结果;秩次型;等级型;筛查;顺序型存在情况;存在;存在与否;是否存在;阈值;界值;界限;阀值;临界值;存在情况（存在、存在与否、是否存在）或阈值（界值、界限、阀值、临界值）干扰素诱导型解旋酶 C 结构域包含型蛋白 1;interferon-induced helicase C domain-containing protein 1 时刻;随机;随意;瞬间血清;血清学;血清学检验项目;血清学检验项目 (非微生物学);血清学检验项目（非微生物学）;血清学检验项目类;血清学检验项目类 (非微生物学);血清学类;血清学类检验项目;血清学类检验项目 (非微生物学);血清学类试验;血清学类试验 (非微生物学);血清学试验;血清学试验 (非微生物学);血清学试验（非微生物学）;血清学试验类 (非微生物学);血清类血清或血浆

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CodeSystem lookup: https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=107563-9

LOINC Copyright

Copyright © Regenstrief Institute, Inc. All Rights Reserved. To the extent included herein, the LOINC table and LOINC codes are copyright © Regenstrief Institute, Inc. and the Logical Observation Identifiers Names and Codes (LOINC) Committee. See https://loinc.org/license for the full LOINC copyright and license.