109932-4
Ganglioside GQ1b IgM Ab [Measurement] in Serum
Trial
Status Information
- Status
- TRIAL
Term Description
This term is intended to collate similar measurements for the LOINC SNOMED CT Collaboration in an ontological view. Additionally, it can be used to communicate a laboratory order, either alone or in combination with specimen or other information in the order. It may NOT be used to report back the measured patient value. https://lo.inc/ce2mb6
Part Descriptions
LP28754-7 Ganglioside GQ1b
Gangliosides are a family of molecules that are present throughout the body but especially prevalent in cells of the nervous system. Specific gangliosides are named for the carbohydrate sequence they contain and have a unique distribution within the nervous system. The oligosaccharide groups on gangliosides act as cell surface markers that play a role in cellular recognition and cell-to-cell communication, and they also act as specific receptors for certain pituitary glycoprotein hormones and certain bacterial protein toxins such as cholera toxin.
Anti-ganglioside antibodies, primarily IgG, are present in the sera from approximately 60% of patients with Guillain-Barré syndrome (GBS), and antibodies against different gangliosides are associated with different forms of GBS.
1. Antibodies against GD1a/GD1b and GD1b/GT1b complexes have been found in patients with more severe GBS requiring mechanical ventilation;
2. Antibodies against GM1 or those against GalNAc-GD1a have been associated with acute motor axonal neuropathy;
3. Anti-GQ1b antibodies are specifically associated with a variant of GBS called Fisher syndrome, which is characterized by ophthalmoplegia and ataxia.
Detection of specific markers early in the course of GBS may help guide the plan of care. PMID: 21214559
Source: Regenstrief LOINC,
PMID: 2121455
LP447904-6 {Measurement}
{Measurement} is a Property grouper part used to collate terms with comparable measurement-related properties. It encompasses the following LOINC Properties: ACnc, AFr, ARat, CAct, CCnc, CCnt, CRat, CSub, EntLen, LaCnc, LnCnc, Mass, MCnc, MCnt, MRat, MRto, MSCnc, MSRat, Naric, NCnc, NFr, Prctl, PrThr, Ratio, SatFr, SCnc, SCnt, SRat, SRto, Sub, ThreshNum, Titr, and TmMCn.
Source: Regenstrief LOINC
LP222219-0 Ganglioside
A ganglioside molecule consists of a glycosphingolipid (ceramide and oligosaccharide) with one or more sialic acid residues linked to the sugar chain. Molecules with one sialic acid residue are called monosialogangliosides (GM), those with two are called disialogangliosides (GD), and those with three are trisialogangliosides (GT). Gangliosides without any sialic acid residues are called asialogangliosides, while those that do not have a ceramide N-acyl group are called lysogangliosides. The number that typically is included at the end of the name indicates the order in which the molecule was discovered. For example, GM2 is a ganglioside with one sialic acid residue that was the second GM to be identified.
Source: Regenstrief LOINC
LOINC Names Get Info
- Fully-Specified Name
- Ganglioside GQ1b Ab.IgM:
{Measurement}: -: Ser: -: - Long Common Name
- Ganglioside GQ1b IgM Ab [Measurement] in Serum
- Short Name
- GQ1b Gangl IgM Msmt Ser
- Display Name
- Ganglioside GQ1b IgM (S) [Measurement]
- Consumer Name Alpha Get Info
- Ganglioside GQ1b IgM antibody, Blood
Part Model Get Info
Basic Attributes
- Class
- LABORDERS.ONTOLOGY
- Type
- Laboratory
- First Released
- Version 2.81
- Last Updated
- Version 2.81 (ADD)
- Order vs. Observation
- Order
Language Variants Get Info
| Tag | Language | Translation |
|---|---|---|
| es-ES | Spanish (Spain) | Gangliósido GQ1b IgM: |
| fr-FR | French (France) | Ganglioside GQ1b Ac IgM: |
| it-IT | Italian (Italy) | Ganglioside GQ1b Ab.IgM: Synonyms: Anticorpi IgM anticorpo Codici richieste di laboratorio LABORDERS.ONTOLOGY Misurazione Siero |
| pl-PL | Polish (Poland) | Gangliozyd GQ1b Ab.IgM: Synonyms: IgM Przeciwciała do gangliozydu GQ1b Przeciwciała IgM do gangliozydu GQ1b |
| zh-CN | Chinese (China) | 神经节苷脂 GQ1b 抗体.IgM: Synonyms: {测量}; |
LOINC Terminology Service (API) using HL7® FHIR® Get Info
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LOINC Copyright
Copyright © Regenstrief Institute, Inc. All Rights Reserved. To the extent included herein, the LOINC table and LOINC codes are copyright © Regenstrief Institute, Inc. and the Logical Observation Identifiers Names and Codes (LOINC) Committee. See https://