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Part Description

LP14400-3   Hepatitis C virus
Hepatitis C virus (HCV) is a small (50 nm in size), enveloped, single-stranded, positive sense RNA virus in the genus hepacivirus, which is in the Flaviviridae family. More than 170 million people worldwide are affected by hepatitis C, and the majority of patients with acute hepatitis C develop chronic HCV infection, which can result in liver cirrhosis, hepatic failure or hepatocellular carcinoma. The HCV core protein is a highly basic, RNA-binding protein that forms the viral capsid. The E1 and E2 envelope glycoproteins are necessary for viral entry and fusion. Non-structural proteins include NS2, NS3, NS4A and 4B, and NS5A and 5B. The NS2-NS3 complex functions as a protease, and NS3 also has a helicase/NTPase domain. NS4A is a cofactor of NS3 protease activity. NS3-NS4A protease is one target of anti-HCV drugs. NS4B is a membrane anchor for the replication complex, and NS5A plays a role in regulating viral replication. NS5B is an RNA-dependent RNA polymerase. [NCBI Books: NBK1630] Source: Regenstrief LOINC, NCBI Books: NBK1630

LOINC Names Get Info

Fully-Specified Name
Hepatitis C virus RNA:PrThr:Pt:Ser/Plas:Ord:Probe.amp.tar
Long Common Name
Hepatitis C virus RNA [Presence] in Serum or Plasma by NAA with probe detection
Short Name
HCV RNA SerPl Ql NAA+probe
Display Name
HCV RNA NAA+probe Ql
Consumer Name Alpha Get Info
Hepatitis C virus (HCV), Blood

Part Model Get Info

  • Component
    Hepatitis C virus RNA
    LP38335-3
    • Analyte
      Hepatitis C virus RNA
      LP38335-3
      • Component Numerator
        Hepatitis C virus RNA
        LP38335-3
        • Component Numerator Core
          Hepatitis C virus
          LP14400-3
        • Component Numerator Core Suffix
          RNA
          LP32423-3
      • Component Denominator
        NULL
         
        • Component Denominator Core
          NULL
           
        • Component Denominator Core Suffix
          NULL
           
    • Challenge
      NULL
       
    • Adjustment
      NULL
       
    • Count
      NULL
       
  • Property
    PrThr
    LP217195-9
  • Time
    Pt
    LP6960-1
  • System
    Ser/Plas
    LP7576-4
    • System Core
      Ser/Plas
      LP7576-4
    • Super System
      NULL
       
  • Scale
    Ord
    LP7751-3
  • Method
    Probe.amp.tar
    LP6464-4

Basic Attributes

Class
MICRO
Type
Laboratory
First Released
Version 1.0j-a
Last Updated
Version 2.73 (MIN)
Change Reason
The PrThr property is used for LOINC terms whose results are reported using an ordered categorical scale, regardless of whether or not an internal threshold was used to make that determination. This change was approved by the Laboratory LOINC Committee in June 2016.
Order vs. Observation
Both
Common Test Rank Get Info
1104

Member of these Panels

LOINCLong Common Name
75888-8HCV RNA screening tests - Meaningful Use set
50023-1Hepatitis C virus RNA panel (viral load) in Serum or Plasma by NAA with probe detection

Member of these Groups Get Info

LOINC GroupGroup Name
LG32754-0Hepatitis C virus

Language Variants Get Info

TagLanguageTranslation
cs-CZCzech (Czechia)Virus hepatitidy C RNA:Přítomnost nebo práh:Časový bod:Sérum/plazma:Ordinální:Amplifikace nukleových kyselin s detekcí sondou
de-ATGerman (Austria)Synonyms: HCV RNA PCR
de-DEGerman (Germany)Hepatitis-C-Virus RNA:Nachweis oder Schwellenwert:Zeitpunkt:Serum oder Plasma:Ordinal:Zielfragmentamplifikation mit Sondendetektion
Synonyms: Hepacivirus C; HCV
el-GRGreek (Greece)Ιός Ηπατίτιδας C RNA:PrThr:Pt:Ορός/Πλάσμα:Ord:Ανιχνευτής.ενίσχυση.στόχου
Synonyms: C MICRO Ord PrThr Pt RNA Ανιχνευτής Ανιχνευτής.ενίσχυση Ανιχνευτής.ενίσχυση.στόχου Ιός Ιός ηπατίτιδας C Ορός Ορός/Πλάσμα Πλάσμα
es-ARSpanish (Argentina)ARN del virus de la hepatitis C:concentración arbitraria:punto en el tiempo:suero/plasma:ordinal:sonda.amplificación.blanco
es-ESSpanish (Spain)Virus Hepatitis C RNA:PrThr:Punto temporal:Suero o Plasma:Ord:Sonda con amplificación dirigida
es-MXSpanish (Mexico)ARN del virus de la hepatitis C:Presencia o umbral:Punto temporal:Suero o Plasma:Ordinal:Amplificación de ácidos nucleicos con detección de sonda
fr-CAFrench (Canada)Virus de l'hépatite C ARN:Présence-Seuil:Temps ponctuel:Sérum/Plasma:Ordinal:Sonde avec amplification de la cible
fr-FRFrench (France)Hépatite C virus ARN:Présence/Seuil:Ponctuel:Sérum/Plasma:Qualitatif:PCR amplification de cible
fr-BEFrench (Belgium)Virus de l'hépatite C ARN:PrThr:Temps ponctuel:Sérum/Plasma:Ordinal:Sonde avec amplification de la cible
Synonyms: HCV
it-ITItalian (Italy)Epatite C, virus RNA:PrThr:Pt:Siero/Plasma:Ord:Sonda.amp.tar
Synonyms: Microbiologia Plasma Presenza o Soglia Punto nel tempo (episodio) Siero Siero o Plasma Sonda con amplificazione Sonda con amplificazione del target Sonda di DNA Virus dell''epatite C
ko-KRKorean (Korea, Republic Of)C형 간염 바이러스 리보핵산:임의농도:검사시점:혈청/혈장:순위척도:DNA 탐색자.증폭.표적
nl-NLDutch (Netherlands)Hepatitis C-virus RNA:aanwezigheid:moment:serum of plasma:ordinaal:probe-detectie
Synonyms: probe.amp.tar
pl-PLPolish (Poland)Wirus zapalenia wątroby typu C RNA:granica wykrywalności:punkt w czasie:surowica lub osocze:uporządkowany:sonda.amplifikacja.cel
Synonyms: amplifikacja kwasu nukleinowego z detekcją za pomocą sondy amplifikacja z detekcją za pomocą sondy RNA wirusa zapalenia wątroby typu C
pt-BRPortuguese (Brazil)Hepatite C vírus RNA:ACnc:Pt:Sor/Plas:Ord:Sonda com limite de detecção da amplificação de alvo
Synonyms: Ribonucleic acid; HCV; Hep C; Arbitrary concentration; Point in time; Random; SerPl; SerPlas; SerP; Serum; SR; Plasma; Pl; Plsm; Ql; Ordinal; QL; Qualitative; Qual; Screen; PCR; Polymerase chain reaction; Transcription mediated amplification; NASBA; Nucleic acid sequence based analysis; SDA; Strand Displacement Amplification; LAT; Ligation-activated transcription; 3SR SR; 3 Self-Sustaining Sequence Replication; LCR; Ligase chain reaction; QBR; Q-Beta Replicase or probe amplification category method; Probe with target amplification; NAAT; TMA; Amp Prb; Probe with ampification; DNA probe; Amplified; Hepatit; Hepatis; Microbiology
ru-RURussian (Russian Federation)Гепатита С вирус РНК:PrThr:ТчкВрм:Сыв/Плаз:Пор:Проба.усил.миш
Synonyms: ДНК проба;ДНК зонд Плазма Порядковый Проба с мишени усилением Сыворотка Сыворотка или Плазма Точка во времени;Момент
tr-TRTurkish (Turkey)Hepatit C virüsü RNA:MevcEşik:Zmlı:Ser/Plaz:Srl:Prob.amf.hdf
Synonyms: Mevcut
uk-UAUkrainian (Ukraine)Вірусу Гепатиту С РНК:Наявність або Поріг:МоментЧасу:Сироватка/Плазма:Порядково:Зонд-детекція. цільова аміпліфікація НК
Synonyms: 3 Self-Sustaining Sequence Replication; 3SR SR; Amplif; Amplification; Amplified; DNA NUCLEIC ACID PROBE; DNA probe; HCV; Hep; Hep C; Hepatis; Hepatit; Hepatology; ID; Infectious Disease; InfectiousDisease; LAT; LCR; Ligase chain reaction; Ligation-activated transcription; Liver; Microbiology; NAA+probe; NAAT; NASBA; Nucleic acid sequence based analysis; Ordinal; PCR; Pl; Plasma; Plsm; Point in time; Polymerase chain reaction; PR; Probe amp; Probe with ampification; Probe with target amplification; QBR; QL; Qual; Qualitative; Random; Ribonucleic acid; Screen; SDA; SerP; SerPl; SerPlas; Serum; Serum or plasma; SR; Strand Displacement Amplification; TMA; Transcription mediated amplification; UniversalLabOrders
zh-CNChinese (China)丙型肝炎病毒 RNA:存在情况或阈值:时间点:血清/血浆:序数型:探针法.基因扩增.靶向
Synonyms: C 型;丙;丙型 HCV RNA HCV;Hep C;丙型肝炎;丙肝;丙肝病毒;肝炎病毒 C 型 Hep C RNA 丙肝病毒 RNA 传染性肝炎 传染毒;传染毒素;滤过性病原体;病毒类;过滤性病原体 依次型;分类顺序型;定性的;序数型（或称等级型）;性质上的;有序型;有序性分类应答;有序性分类结果;秩次型;等级型;筛查;顺序型 借助扩增的探针方法;借助扩增的探针法;探针法.扩增 借助靶向扩增的探针方法;借助靶向扩增的探针法;探针法.扩增.靶向 存在情况;存在;存在与否;是否存在;阈值;界值;界限;阀值;临界值;存在情况（存在、存在与否、是否存在）或阈值（界值、界限、阀值、临界值） 微生物学;微生物学试验;微生物学试验（培养、DNA、抗原及抗体） 扩增型 扩增性 时刻;随机;随意;瞬间 核糖核酸;Ribonucleic acid 经过扩增的 肝 肝炎病毒 C 型 RNA 脱氧核糖核酸探针 血清或血浆

LOINC Terminology Service (API) using HL7® FHIR® Get Info

CodeSystem lookup
https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=11259-9