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Part Descriptions

LP102596-6   Norhydrocodone
Norhydrocodone is a metabolite of hydrocodone, a narcotic analgesic related to codeine, but more potent and more addicting by weight. It is used also as cough suppressant. Drug testing of pain patients provides objective information to health specialists regarding patient compliance, diversion, and concurrent illicit drug use. The interpretation of test results can be difficult however because of complex biotransformations of parent drug to metabolites that are also available commercially and may be abused. Additional testing for normetabolites, such as norhydrocodone, provides conclusive evidence that the parent drug was consumed and is helpful in interpreting the opiate drug source, and also reduces potential false negatives. PMID: 20036472 Source: Regenstrief LOINC, PMID: 20036472

LP7565-7   Saliva
Saliva is produced primarily by the parotid, submaxillary, and sublingual glands. It is secreted at the rate of 0-3 milliliters per minute which is affected by various factors including anxiety, hydration and hunger. Oral fluid is broadly used to test for drugs of abuse in employment and forensic settings, and is especially useful since it is difficult to adulterate, is quick and is non-invasive. Oral fluid is used to test a variety of analytes, including to test alcohol, HIV and other antibodies, therapeutic drugs and steroids, but its primary use is to test for drugs of abuse including amphetamines, cocaine and metabolites, opioids, methadone, cannabis and heroin. PMID: 17268583 Source: Regenstrief LOINC

LP262420-5   Saliva DRUG/TOX
Oral fluid (or saliva) is produced primarily by the parotid, submaxillary, and sublingual glands. It is secreted at the rate of 0-3 milliliters per minute which is affected by various factors including anxiety, hydration and hunger. Oral fluid is broadly used to test for drugs of abuse in employment and forensic settings, and is especially useful since it is difficult to adulterate, is quick and is non-invasive. Oral fluid is used to test a variety of analytes, including to test alcohol, HIV and other antibodies, therapeutic drugs and steroids, but its primary use is to test for drugs of abuse including amphetamines, cocaine and metabolites, opioids, methadone, cannabis and heroin. The test procedures that use oral fluid for drug screening are usually similar to those for other specimens but adapted for oral fluid. Oral fluid is broadly used to test for drugs of abuse in employment and forensic settings, and is especially useful since it is difficult to adulterate, is quick and is non-invasive. Drugs present in oral fluid are often the parent drug rather than a metabolite and tests kits reflect those differences. Concentrations of cocaine, amphetamines and some opioids in oral fluid are either similar or higher than concentrations in plasma. The concentration of tetrahydrocannabinol (THC) in oral fluid is similar to that of plasma, though in cases where recent ingestion has occurred, levels may be higher due to the significant local absorption in the oral cavity. Confirmatory testing on oral fluid using liquid chromatography-mass spectrometry (LC-MS) is highly sensitive and specific even on relatively small sample sizes. An increased understanding of pharmacokinetics in oral fluid has flourished inover the last ten years has allowed the correlation of . As a result, the concentrations of various drugs in oral fluid have been correlated to blood concentrations and the effects they have on the individual. PMID: 17268583 Source: Regenstrief LOINC

LOINC Names Get Info

Fully-Specified Name
Norhydrocodone:PrThr:Pt:Saliva:Ord:Mass Spec
Long Common Name
Norhydrocodone [Presence] in Saliva (oral fluid) by Mass Spectrometry
Short Name
Norhydrocodone Sal Ql Mass Spec
Display Name
Norhydrocodone Mass Spec Ql (Sal)
Consumer Name Alpha Get Info
Norhydrocodone, Saliva

Part Model Get Info

  • Component
    Norhydrocodone
    LP102596-6
    • Analyte
      Norhydrocodone
      LP102596-6
      • Component Numerator
        Norhydrocodone
        LP102596-6
        • Component Numerator Core
          Norhydrocodone
          LP102596-6
        • Component Numerator Core Suffix
          NULL
           
      • Component Denominator
        NULL
         
        • Component Denominator Core
          NULL
           
        • Component Denominator Core Suffix
          NULL
           
    • Challenge
      NULL
       
    • Adjustment
      NULL
       
    • Count
      NULL
       
  • Property
    PrThr
    LP217195-9
  • Time
    Pt
    LP6960-1
  • System
    Saliva
    LP7565-7
    • System Core
      Saliva
      LP7565-7
    • Super System
      NULL
       
  • Scale
    Ord
    LP7751-3
  • Method
    Mass Spec
    LP451714-2

Example Answer List: LL744-4

Source: Regenstrief Institute
AnswerCodeScoreAnswer ID
DetectedLA11882-0
Not detectedLA11883-8

Basic Attributes

Class
DRUG/TOX
Type
Laboratory
First Released
Version 2.83
Last Updated
Version 2.83 (ADD)
Order vs. Observation
Both

Member of these Groups Get Info

LOINC GroupGroup Name
LG53039-0Norhydrocodone|PrThr|Pt|Saliva

LOINC Terminology Service (API) using HL7® FHIR® Get Info

CodeSystem lookup
https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=113270-3