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Part Description

LP14853-3   Varicella zoster virus
Varicella zoster virus (VZV) is a double-stranded alphaherpesvirus that causes seasonal outbreaks of chickenpox and shingles in non-immunized populations. VZV is highly infectious and is transmitted by contact with the ruptured fluid filled blisters and respiratory secretions of infected individuals. Immunity post infection is usually lifelong though the latent virus inhabits the sensory nerve ganglia where it can reactivate causing shingles when immunity declines with aging.http://jvi.asm.org/content/88/24/13936.full In the over fifty strains of VZV that have been sequenced it has been found that a single nucleotide polymorphism occurs about every 100 bases. The patterns of polymorphisms in VZV correlate with different geographical regions of infection and is the basis for the classification of viral clades.https://grose.lab.uiowa.edu/vzv-genomes-and-evolution Breuer proposed the nomenclature for the VZV clades as 1-5 with the suspected clades VI and VII to be confirmed later. The geographical regions associated with the seven clades are as follows:
Clades 1 and 3-represent the dominant clades of the circulating VZV in Europe and the Americas
Clades 4 and 5-found in Africa
Clade VI found in France, Italy
Clade VII exclusively isolated in the US
Clade 2-Asia from Korea, Japan, China not found in India, Nepal and Bangladesh where clades 4 and 5 were dominant
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5054591/ Source: Regenstrief LOINC

LOINC Names Get Info

Fully-Specified Name
Varicella zoster virus DNA:PrThr:Pt:{Specimen}:Ord:{Molgen}
Long Common Name
Varicella zoster virus DNA [Presence] in Specimen by Molgen
Short Name
VZV DNA Spec Ql
Display Name
VZV DNA Molgen Ql (Specimen)
Consumer Name Alpha Get Info
Varicella zoster virus (VZV; Chickenpox), Specimen

Part Model Get Info

  • Component
    Varicella zoster virus DNA
    LP40115-5
    • Analyte
      Varicella zoster virus DNA
      LP40115-5
      • Component Numerator
        Varicella zoster virus DNA
        LP40115-5
        • Component Numerator Core
          Varicella zoster virus
          LP14853-3
        • Component Numerator Core Suffix
          DNA
          LP32416-7
      • Component Denominator
        NULL
         
        • Component Denominator Core
          NULL
           
        • Component Denominator Core Suffix
          NULL
           
    • Challenge
      NULL
       
    • Adjustment
      NULL
       
    • Count
      NULL
       
  • Property
    PrThr
    LP217195-9
  • Time
    Pt
    LP6960-1
  • System
    {Specimen}
    LP451871-0
  • Scale
    Ord
    LP7751-3
  • Method
    {Molgen}
    LP452305-8

Basic Attributes

Class
MICRO
Type
Laboratory
First Released
Version 2.83
Last Updated
Version 2.83 (ADD)
Order vs. Observation
Both

Member of these Groups Get Info

LOINC GroupGroup Name
LG32750-8Varicella zoster virus

LOINC Terminology Service (API) using HL7® FHIR® Get Info

CodeSystem lookup
https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=114525-9