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Part Descriptions

LP146623-6   Plasmodium knowlesi
Plasmodium knowlesi is a primate malaria parasite commonly found in Southeast Asia. It causes malaria in long-tailed macaques (Macaca fascicularis), but it may also infect humans, either naturally or artificially.

Plasmodium knowlesi is the fifth major human malaria parasite. It may cause severe malaria as indicated by its asexual erythrocytic cycle of about 24 hours, with an associated fever that typically occurs at the same frequency (i.e. the fever is quotidian). This is an emerging infection that was reported for the first time in humans in 1965. It accounts for up to 70% of malaria cases in certain areas in South East Asia where it is mostly found. This parasite is transmitted by the bite of an Anopheles mosquito. Plasmodium knowlesi has health, social and economic consequences for the regions affected by it.

Although the current infection rate with Plasmodium knowlesi is relatively low, one risk it presents is misdiagnosis with other forms of malarial parasites such as P. malariae especially when microscopy is used. P. knowlesi can only be accurately distinguished from P. malariae using PCR assay and/or molecular characterization.

Because P. knowlesi takes only 24 hours to complete its erythrocytic cycle, it can result in very high parasite density quickly and may be fatal in humans. For this reason early treatment is advised. It responds well to treatment with chloroquine and primaquine. but if parasite counts are high and patients are severe, then infections should be treated as intensively as for severe falcipaum malaria. Copyright Text is available under the Creative Commons Attribution/Share-Alike License. See http://creativecommons.org/licenses/by-sa/3.0/ for details. Source: Wikipedia, Wikipedia

LP20149-8   Plasmodium
Malaria is a parasitic disease that is passed from one human to another by the bite of an infected Anopheles mosquito with one of four protozoan parasites: Plasmodium falciparum, vivax, malariae or ovale. The parasites enter the bloodstream and infect red blood cells where they multiply and infect more red blood cells. Symptoms usually occur 10 days to 4 weeks after infection and include anemia, high fevers, shaking chills, muscle pain, and nausea. Antimalarial agents used to treat malaria include Quinine, Quinidine, Mefloquine, Chloroquine, and Hydroxychloroquine. The effectiveness of the agents depends on which phase or phases of the Plasmodium life cycle is interrupted. In most cases, treatment outcome is expected to be good except in cases of a p. falciparum infection. Adverse effects from antimalaria medications include vomiting, diarrhea, headaches, cardiac arrhythmias, EKG abnormalities, deafness, damage to liver and kidney and muscle weakness. Source: NMS labs

LOINC Names Get Info

Fully-Specified Name
Plasmodium knowlesi DNA:PrThr:Pt:{Specimen}:Ord:{Molgen}
Long Common Name
Plasmodium knowlesi DNA [Presence] in Specimen by Molgen
Short Name
P knowlesi DNA Spec Ql
Display Name
P. knowlesi DNA Molgen Ql (Specimen)
Consumer Name Alpha Get Info
Plasmodium knowlesi, Specimen

Part Model Get Info

Basic Attributes

Class
MICRO
Type
Laboratory
First Released
Version 2.83
Last Updated
Version 2.83 (ADD)
Order vs. Observation
Both

Member of these Groups Get Info

LOINC GroupGroup Name
LG41640-0Plasmodium

LOINC Terminology Service (API) using HL7® FHIR® Get Info

CodeSystem lookup
https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=114739-6