115263-6
Chikungunya virus RNA [Presence] in Specimen by Molgen
Active
Part Descriptions
LP21132-3 Chikungunya virus
A species of ALPHAVIRUS causing an acute dengue-like fever.
Source: National Library of Medicine, MeSH 2006
LP21132-3 Chikungunya virus
Chikungunya virus (CHIKV) belongs to the mosquito-borne alphavirus genus, in the family Togaviridae, and was first observed in epidemic form in Africa. Serologically, CHIKV belongs to the Semliki Forest (SF) subgroup of alphaviruses. Infection in humans is characterized by rash, high fever and, its hallmark feature, severe arthritis that can persist for years. CHIKV is a small, spherical, enveloped, positive-strand RNA virus. The virion consists of an envelope and a nucleocapsid. The envelope glycoproteins of alphaviruses are the distinguishing factors for testing. The CHIKV genome encodes for two polyproteins; the non-structural polyprotein consisting of four proteins (nsP1, nsP2, nsP3 and nsP4) and the structural polyprotein consisting of five proteins (Capsid, E3, E2, 6K and E1). CHIKV has spikes on the virion surface that are each formed by three E1-E2 heterodimers, where the E1 glycoproteins mediate fusion and E2 glycoproteins interact with the host receptor. PMID: 20111039
CHIKV can be detected between the first and fourth day of infection (the acute phase) using PCR or virus cultivation, and virus-specific IgM and IgG antibodies can be detected during the 8th to the 10th day of infection. Antibody investigation should be performed using serum samples from the acute and convalescent stage.
Source: Regenstrief LOINC
LOINC Names Get Info
- Fully-Specified Name
- Chikungunya virus RNA:
PrThr: Pt: {Specimen}: Ord: {Molgen} - Long Common Name
- Chikungunya virus RNA [Presence] in Specimen by Molgen
- Short Name
- CHIKV RNA Spec Ql
- Display Name
- CHIKV RNA Molgen Ql (Specimen)
- Consumer Name Alpha Get Info
- Chikungunya virus, Specimen
Part Model Get Info
- Component
- Chikungunya virus RNA
LP66615-3
- Analyte
- Chikungunya virus RNA
LP66615-3
- Challenge
- NULL
- Adjustment
- NULL
- Count
- NULL
- Property
- PrThr
LP217195-9
- Time
- Pt
LP6960-1
- Time Core
- Pt
LP6960-1
- Time Modifier
- NULL
- System
- {Specimen}
LP451871-0
- System Core
- {Specimen}
LP451871-0
- Super System
- NULL
- Scale
- Ord
LP7751-3
- Method
- {Molgen}
LP452305-8
Basic Attributes
- Class
- MICRO
- Type
- Laboratory
- First Released
- Version 2.83
- Last Updated
- Version 2.83 (ADD)
- Order vs. Observation
- Both
Member of these Groups Get Info
| LOINC Group | Group Name |
|---|---|
| LG51028-5 | Chikungunya virus |
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LOINC Copyright
Copyright © Regenstrief Institute, Inc. All Rights Reserved. To the extent included herein, the LOINC table and LOINC codes are copyright © Regenstrief Institute, Inc. and the Logical Observation Identifiers Names and Codes (LOINC) Committee. See https://