115342-8
Borrelia garinii+afzelii oppA1 gene [Presence] in Specimen by Molgen
Active
Part Descriptions
LP220480-0 Borrelia garinii+afzelii oppA1 gene
Lyme disease is a multisystem, multistage infection caused by three species of tick-borne spirochetes in the Borrelia burgdorferi sensu lato genogroup. These spirochetes include B. burgdorferi sensu stricto (North America and Western Europe), B. afzelii (Central and Western Europe and Russia), and B. garinii (Europe, Russia, and northern Asia). Endemic areas for Lyme disease in the United States correspond with the distribution of two tick species, Ixodes dammini (Northeastern and Upper Midwestern US) and Ixodes pacificus (West Coast US). In Europe, Ixodes ricinus transmits the spirochete. Human Lyme borreliosis, the most prevalent arthropod-borne infection in temperate climate zones around the world, is an inflammatory disorder characterized by the skin lesion erythema migrans and the potential development of neurologic, cardiac, and joint abnormalities. B. garinii, the most neurotropic of these three genospecies, causes most neurologic Lyme disease in Europe, including cases of meningopolyneuritis and, rarely, encephalomyelitis. Although probably all three genospecies can cause all major manifestations, it appears that infection with different B. burgdorferi sensu lato genospecies results in distinct presentations of Lyme borreliosis. In Europe, B. afzelii is mostly associated with skin manifestations, such as erythema migrans, and acrodermatitis chronica atrophicans, whereas B. garinii is the main cause of Lyme neuroborreliosis. Patients with B. garinii isolated from CSF samples have a distinct clinical presentation, compared with that of patients with B. afzelii infection. PMID: 16912943 PMID: 12454161
Source: Regenstrief LOINC
LP220480-0 Borrelia garinii+afzelii oppA1 gene
The oppA1 gene is a member of a family of three genes; oppA-1, oppA-2, and oppA-3, that encode predicted peptide-binding proteins. Peptide-binding protein dependent transport systems are recognized to play important roles in microbial cell signaling and virulence. PMID: 9712756
Source: Regenstrief LOINC
LOINC Names Get Info
- Fully-Specified Name
- Borrelia garinii+afzelii oppA1 gene:
PrThr: Pt: {Specimen}: Ord: {Molgen} - Long Common Name
- Borrelia garinii+afzelii oppA1 gene [Presence] in Specimen by Molgen
- Short Name
- B gar+afz oppA1 Spec Ql
- Display Name
- B. garinii+afzelii oppA1 gene Molgen Ql (Specimen)
- Consumer Name Alpha Get Info
- Borrelia garinii+afzelii oppA1 gene, Specimen
Part Model Get Info
- Component
- Borrelia garinii+afzelii oppA1 gene
LP220480-0
- Analyte
- Borrelia garinii+afzelii oppA1 gene
LP220480-0
- Component Numerator
- Borrelia garinii+afzelii oppA1 gene
LP220480-0
- Component Numerator Core
- Borrelia garinii+afzelii oppA1 gene
LP220480-0
- Component Numerator Core Suffix
- NULL
- Component Denominator
- NULL
- Component Denominator Core
- NULL
- Component Denominator Core Suffix
- NULL
- Challenge
- NULL
- Adjustment
- NULL
- Count
- NULL
- Property
- PrThr
LP217195-9
- Time
- Pt
LP6960-1
- Time Core
- Pt
LP6960-1
- Time Modifier
- NULL
- System
- {Specimen}
LP451871-0
- System Core
- {Specimen}
LP451871-0
- Super System
- NULL
- Scale
- Ord
LP7751-3
- Method
- {Molgen}
LP452305-8
Basic Attributes
- Class
- MICRO
- Type
- Laboratory
- First Released
- Version 2.83
- Last Updated
- Version 2.83 (ADD)
- Order vs. Observation
- Both
LOINC Terminology Service (API) using HL7® FHIR® Get Info
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LOINC Copyright
Copyright © Regenstrief Institute, Inc. All Rights Reserved. To the extent included herein, the LOINC table and LOINC codes are copyright © Regenstrief Institute, Inc. and the Logical Observation Identifiers Names and Codes (LOINC) Committee. See https://