11577-4

Sulfamethoxazole [Susceptibility] by Gradient strip

Active

Part Descriptions

LP14550-5   Sulfamethoxazole
Sulfamethoxazole is a sulfonamide bacteriostatic antibiotic. It is most often used as part of a synergistic combination with trimethoprim in a 5:1 ratio in co-trimoxazole, which is also known as Bactrim or Septrin. It can be used as an alternative to amoxicillin -based antibiotics to treat sinusitis. Mechanism of action:Sulfonamides are structural anologs and competitive antagonists of para-aminobenzoic acid (PABA). They inhibit normal bacterial utilization of PABA for the synthesis of folic acid, an important metabolite in DNA synthesis. The effects seen are usually bacteriostatic in nature. Folic acid is not synthesized in humans, but is instead a dietary requirement. This allows for the selective toxicity to bacterial cells (or any cell dependent on synthesizing folic acid) over human cells. Copyright Text is available under the Creative Commons Attribution/Share-Alike License. See http://creativecommons.org/licenses/by-sa/3.0/ for details. Source: Wikipedia, Sulfamethoxazole (Wikipedia)

LP6300-0   Gradient strip
A gradient strip is a reagent strip that contains a predefined concentration gradient of a specific antibiotic or combination of antibiotics that is used for antimicrobial susceptibility testing (AST) and antimicrobial resistance detection (ARD).
For AST, the result is reported in terms of the minimum inhibitory concentration (MIC) of a specific antimicrobial that prevents the visible growth of bacteria. In LOINC, the "Gradient strip" method is used for AST gradient strips that result in an MIC result.
For ARD, the result is reported as the presence or absence of a specific enzyme or other mechanism that confers resistance, which is determined based on comparing the inhibitory concentration (IC) of a specific antimicrobial with the IC of that antimicrobial plus a resistance inhibitor. In LOINC, the "Gradient strip ARD" method is used for ARD gradient strips, which are not intended for determining individual MIC values. Source: Regenstrief LOINC

Fully-Specified Name

Component

Sulfamethoxazole

Property

Susc

Time

Pt

System

Isolate

Scale

OrdQn

Method

Gradient strip

Additional Names

Short Name

Sulfamethoxazole Islt Grad strip

Display Name

Sulfamethoxazole Strip [Susc]

Consumer Name Alpha Get Info

Susceptibility to Sulfamethoxazole

Basic Attributes

Class

ABXBACT

Type

Laboratory

First Released

Version 1.0j-a

Last Updated

Version 2.56

Change Reason

Feb 2016-removed "E-test" from the short and long names because the "ETEST" name is trademarked

Order vs. Observation

Observation

Member of these Panels

Member of these Groups Get Info

Language Variants Get Info

Related Names

• Acetylsulfamethoxazole
• ANTIBIOTIC SUSCEPTIBILITIES
• AST
• c203
• c223
• C61
• Epsilometer
• Estrip
• E-strip
• Gantanol
• Grad strip
• ID
• Infectious Disease
• InfectiousDisease
• Islt
• Isol
• MIC
• Minimum inhibitory concentration
• Point in time
• Random
• SMX
• Sulfa
• Sulfamethox
• Sus
• Suscept
• Susceptibilities
• Susceptibility
• Susceptibilty

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CodeSystem lookup

https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=11577-4

LOINC Copyright

Copyright © 2024 Regenstrief Institute, Inc. All Rights Reserved. To the extent included herein, the LOINC table and LOINC codes are copyright © 1995-2024, Regenstrief Institute, Inc. and the Logical Observation Identifiers Names and Codes (LOINC) Committee. See https://loinc.org/license for the full LOINC copyright and license.