115770-0

Methotrexate --trough [Moles/volume] of Serum

Active

Part Descriptions

LP16198-1 Methotrexate
High-dose methotrexate (MTX) is an antimetabolite drug used in treatment of cancer, and low-dose methotrexate (MTX) is used as a disease modifying antirheumatic drug (DMARD) for long-term treatment of rheumatoid arthritis (RA), psoriasis, and other autoimmune diseases. Methotrexate is a first-line drug in RA treatment. One challenge in the use of the drug is that about 30% of patients do not respond to treatment or experience adverse effects, such as gastrointestinal symptoms, malaise, and psychological complaints. PMID: 20665136 Source: Regenstrief LOINC, PMID: 20665136

LP20176-1 trough
In medicine, a trough level is the lowest level that a medicine is present in the body. In a medicine that is administered periodically, the trough level should be measured just before the administration of the next dose in order to avoid overdosing. It should be contrasted with a "peak level", which is the highest level of the medicine in the body, and the "average level", which is the mean level over time. It helps in therapeutic drug monitoring. It is widely used in clinical trials for newer medicines for its therapeutic effectiveness and safety. Copyright Text is available under the Creative Commons Attribution/Share-Alike License. See http://creativecommons.org/licenses/by-sa/3.0/ for details. Source: Wikipedia, Trough levels for therapeutic drug monitoring

LOINC Names Get Info

Fully-Specified Name: Methotrexate^trough:SCnc:Pt:Ser:Qn:
Long Common Name: Methotrexate --trough [Moles/volume] of Serum
Short Name: MTX Trough Ser-sCnc
Display Name: Methotrexate trough (S) [Moles/Vol]
Consumer Name Alpha Get Info: Methotrexate trough, Blood

Part Model Get Info

Component
Methotrexate^trough
LP453304-0
- Analyte
  Methotrexate
  LP16198-1
  - Component Numerator
    Methotrexate
    LP16198-1
    - Component Numerator Core
      Methotrexate
      LP16198-1
    - Component Numerator Core Suffix
      NULL
  - Component Denominator
    NULL
    - Component Denominator Core
      NULL
    - Component Denominator Core Suffix
      NULL
- Challenge
  trough
  LP20176-1
- Adjustment
  NULL
- Count
  NULL
Property
SCnc
LP6860-3
Time
Pt
LP6960-1
- Time Core
  Pt
  LP6960-1
- Time Modifier
  NULL
System
Ser
LP7567-3
- System Core
  Ser
  LP7567-3
- Super System
  NULL
Scale
Qn
LP7753-9
Method
NULL

Basic Attributes

Class: DRUGDOSE
Type: Laboratory
First Released: Version 2.83
Last Updated: Version 2.83 (ADD)
Order vs. Observation: Both

Language Variants Get Info

Tag	Language	Translation
el-GR	Greek (Greece)	Μεθοτρεξάτη^ελάχιστα επίπεδα:SCnc:Pt:Ορός:Qn: Synonyms: DRUGDOSE Pt Qn SCnc ελάχιστα επίπεδα Μεθοτρεξάτη Ορός
es-ES	Spanish (Spain)	Metotrexato^Valle monitorización terapéutica de fármacos:Concentración de sustancia:Punto temporal:Suero:Qn: Synonyms: Cuantitativo
et-EE	Estonian (Estonia)	Metotreksaat^baas:SCnc:Pt:S:Qn: Synonyms: Aine kontsentratsioon Juhuslik Kvantitatiivne Seerum
fr-CA	French (Canada)	Méthotrexate^Creux:Concentration de substance:Temps ponctuel:Sérum:Quantitatif:
fr-FR	French (France)	Méthotrexate^taux résiduel:Moles/Volume:Ponctuel:Sérum:Numérique:
fr-BE	French (Belgium)	Méthotrexate^Creux:Concentration de substance:Temps ponctuel:Sérum:Quantitatif: Synonyms: Minimum, nadir
it-IT	Italian (Italy)	Metotrexato^valore minimo:SCnc:Pt:Siero:Qn: Synonyms: Concentrazione di Sostanza Dosaggio farmacologico (per la trasmissione di dos Punto nel tempo (episodio) Siero valore minimo TDM
nl-NL	Dutch (Netherlands)	methotrexaat^dalspiegel:mol/volume:moment:serum:kwantitatief:
ru-RU	Russian (Russian Federation)	Метотрексат^остаточная концентрация:МолКонц:ТчкВрм:Сыв:Колич: Synonyms: Количественный минимум концентрации Молярность;Молярная объёмная концентрация Сыворотка Точка во времени;Момент
tr-TR	Turkish (Turkey)	Metotreksat^en düşük:SubKons:Zmlı:Ser:Kant: Synonyms: çukur düzey
zh-CN	Chinese (China)	氨甲喋呤^波谷:物质的量浓度:时间点:血清:定量型: Synonyms: C20H22N8O5;甲氨喋呤;氨甲基叶酸;氨甲蝶呤;甲基蝶啶胺;甲基蝶啶胺(化学不孕剂) 一剂药物的初始剂量;初始剂量;剂量药物的初始剂量;前剂量;曲线上的最小值;最低点;本底剂量;治疗药物监测 - 波谷;预剂量克分子浓度;克分子浓度(单位体积);摩尔浓度;摩尔浓度(单位体积);物质的量浓度(单位体积) 可用数量表示的;定量性;数值型;数量型;连续数值型标尺时刻;随机;随意;瞬间药物剂量

Example Units

Unit	Source
umol/L	Example UCUM Units

LOINC Terminology Service (API) using HL7^® FHIR^® Get Info

CodeSystem lookup: https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=115770-0

LOINC Copyright

Copyright © Regenstrief Institute, Inc. All Rights Reserved. To the extent included herein, the LOINC table and LOINC codes are copyright © Regenstrief Institute, Inc. and the Logical Observation Identifiers Names and Codes (LOINC) Committee. See https://loinc.org/license for the full LOINC copyright and license.