Log In

Part Description

LP18384-5   Mitotane
Dichlorodiphenyldichloroethane (o,p'- DDD or Mitotane) is an isomer of 4,4′-Dichlorodiphenyldichloroethane (p,p'DDD) used broadly as a pesticide. as well as an oral chemotherapeutic drug used to treat Cushing's syndrome and adrenal cortical carcinoma. o,p'- DDD directly suppresses the adrenal cortex and alters the degradation of steroids. Despite the ability of o,p'- DDD to prevent excess hormone production, its side-effects are difficult to tolerate. The adverse reactions include the following:
• gastrointestinal disorders: 80% of patients endured anorexia, nausea or vomiting, diarrhea
• central nervous system: 40% of patients experience depression in the form of lethargy and somnolence (25%) and dizziness and vertigo (15%)
• skin toxicity: 15% of patients transient rashes
• infrequently occurring adverse effects include: visual blurring, diplopia, lens opacity, toxic retinopathy, hematuria, hemorrhagic cystitis, albuminuria, hypertension, orthostatic hypotension, flushing, generalized aching, hyperpyrexia, lowered protein bound iodine
http://flipper.diff.org/app/items/info/2929[CID: 6294] Source: Regenstrief LOINC

LOINC Names Get Info

Fully-Specified Name
Mitotane:MCnc:Pt:Ser/Plas:Qn:
Long Common Name
Mitotane [Mass/volume] in Serum or Plasma
Short Name
Mitotane SerPl-mCnc
Display Name
Mitotane [Mass/Vol]
Consumer Name Alpha Get Info
Mitotane, Blood

Part Model Get Info

  • Component
    Mitotane
    LP18384-5
    • Analyte
      Mitotane
      LP18384-5
      • Component Numerator
        Mitotane
        LP18384-5
        • Component Numerator Core
          Mitotane
          LP18384-5
        • Component Numerator Core Suffix
          NULL
           
      • Component Denominator
        NULL
         
        • Component Denominator Core
          NULL
           
        • Component Denominator Core Suffix
          NULL
           
    • Challenge
      NULL
       
    • Adjustment
      NULL
       
    • Count
      NULL
       
  • Property
    MCnc
    LP6827-2
  • Time
    Pt
    LP6960-1
  • System
    Ser/Plas
    LP7576-4
    • System Core
      Ser/Plas
      LP7576-4
    • Super System
      NULL
       
  • Scale
    Qn
    LP7753-9
  • Method
    NULL
     

Basic Attributes

Class
DRUG/TOX
Type
Laboratory
First Released
Version 1.0k
Last Updated
Version 2.73 (MIN)
Order vs. Observation
Both
Common Test Rank Get Info
5880

Language Variants Get Info

TagLanguageTranslation
ar-JOArabic (Jordan)المايتوتان في المصل أو البلازما ( بتقنية الكتلة / الحجم )
cs-CZCzech (Czechia)Mitotan:Hmotnostní koncentrace:Časový bod:Sérum/plazma:Kvantitativní:
el-GRGreek (Greece)Μιτοτάνη:MCnc:Pt:Ορός/Πλάσμα:Qn:
Synonyms: DRUG/TOX MCnc Pt Qn Μιτοτάνη Ορός Ορός/Πλάσμα Πλάσμα
es-ARSpanish (Argentina)mitotano:concentración de masa:punto en el tiempo:suero/plasma:cuantitativo:
es-ESSpanish (Spain)Mitotano:Concentración de masa:Punto temporal:Suero o Plasma:Qn:
Synonyms: Cuantitativo
es-MXSpanish (Mexico)Mitotano:Concentración de masa:Punto temporal:Suero o Plasma:Cuantitativo:
et-EEEstonian (Estonia)Mitotaan:MCnc:Pt:S/P:Qn:
Synonyms: Juhuslik Kvantitatiivne Plasma Seerum Seerum või plasma
fr-CAFrench (Canada)Mitotane:Concentration de masse:Temps ponctuel:Sérum/Plasma:Quantitatif:
fr-FRFrench (France)Mitotane:Masse/Volume:Ponctuel:Sérum/Plasma:Numérique:
fr-BEFrench (Belgium)Mitotane:Concentration de masse:Temps ponctuel:Sérum/Plasma:Quantitatif:
it-ITItalian (Italy)Mitotane:MCnc:Pt:Siero/Plasma:Qn:
Synonyms: Concentrazione di Massa Livelli farmacologici e tossicologia Mitotano Plasma Punto nel tempo (episodio) Siero Siero o Plasma
ko-KRKorean (Korea, Republic Of)마이토테인:질량농도:검사시점:혈청/혈장:정량:
nl-NLDutch (Netherlands)mitotaan:massa/volume:moment:serum of plasma:kwantitatief:
pt-BRPortuguese (Brazil)Mitotano:MCnc:Pt:Sor/Plas:Qn:
Synonyms: o,p'-DDD; Lysodren; Mass concentration; Level; Point in time; Random; SerPl; SerPlas; SerP; Serum; SR; Plasma; Pl; Plsm; Quantitative; QNT; Quant; Quan; Drugs; DRUG/TOXICOLOGY; DRUG/TOXICOLOGY
ru-RURussian (Russian Federation)Митотан:МассКонц:ТчкВрм:Сыв/Плаз:Колич:
Synonyms: Количественный Массовая концентрация Плазма Сыворотка Сыворотка или Плазма Точка во времени;Момент
tr-TRTurkish (Turkey)Mitotan:KütlKons:Zmlı:Ser/Plaz:Kant:
zh-CNChinese (China)米托坦:质量浓度:时间点:血清/血浆:定量型:
Synonyms: 可用数量表示的;定量性;数值型;数量型;连续数值型标尺 时刻;随机;随意;瞬间 毒品 毒品类 水平;浓度;质量浓度(单位体积) 药品类 药物 药物/毒理学;药物/毒理学试验;药物毒理学试验;药物毒理学试验类 药物类 血清或血浆 邻氯苯对氯苯二氯乙烷;曼托坦;双氯苯二氯乙烷;氯苯二氯乙烷;1-(2-chlorophenyl)-1-(4-chlorophenyl)-2,2-dichloroethane;1-(2-Chlorophenyl)-1-(4-chlorophenyl)-2,2-dichlor;Mitotane;2,2,o,p-tetrachloroethylidenebisbenzene;Mitotan;CAS 53-19-0;EINECS 200-166-6;C14H10Cl4

Example Units

UnitSource
ug/mLExample UCUM Units

LOINC Terminology Service (API) using HL7® FHIR® Get Info

CodeSystem lookup
https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=13626-7