13804-0

Pyridinoline/Creatinine [Mass Ratio] in 2 hour Urine

Discouraged

Status Information

Status: DISCOURAGED
Comment: Most laboratories report this in moles. Double check with your lab for reporting units.

Map-To	Long Common Name	Mapping Guidance
25131-4	Pyridinoline/Creatinine [Molar ratio] in 2 hour Urine

Part Descriptions

LP14914-3 Pyridinoline
Pyridinoline is a fluorescent cross-linking compound of collagen fibers. Crosslinks in collagen and elastin are derived from lysyl and hydroxylysyl residues, a process catalyzed by lysyl oxidase. Fujimoto and colleagues first described the isolation and characterization of a fluorescent material in bovine achilles tendon collagen and termed it pyridinoline. It is reported to be present in collagen of bone and cartilage, but is absent in collagen of skin. It is not present in newly synthesized collagen and is formed from aldimine cross-links during maturation of collagen fibers.

Pyridinoline and deoxypyridinoline were found to be released into the blood during bone degradation and rapidly exereted in the urine. In a preliminary study, both these compounds were proposed as a marker for metastatic bone tumor in patients with prostate cancer. Copyright Text is available under the Creative Commons Attribution/Share-Alike License. See http://creativecommons.org/licenses/by-sa/3.0/ for details. Source: Wikipedia, Wikipedia

LP32035-5 Creatinine
Creatinine or creatine anhydride, is a breakdown product of creatine phosphate in muscle. The loss of water molecule from creatine results in the formation of creatinine. It is transferred to the kidneys by blood plasma, whereupon it is eliminated by glomular filtration and partial tubular excretion. Creatinine is usually produced at a fairly constant rate and measuring its serum level is a simple test. A rise in blood creatinine levels is observed only with marked damage to functioning nephrons; therefore this test is not suitable for detecting early kidney disease. Creatine and creatinine are metabolized in the kidneys, muscle, liver and pancreas. Copyright Copyright ©2005-2009 Genome Alberta (Reference to original publication: Wishart DS, Knox C, Guo AC, et al. HMDB: a knowledgebase for the human metabolome. Nucleic Acids Res. 2009 37(Database issue):D603-610.) Source: Human Metabolome Database, Creatinine

LOINC Names Get Info

Fully-Specified Name: Pyridinoline/Creatinine:MRto:2H:Urine:Qn:
Long Common Name: Pyridinoline/Creatinine [Mass Ratio] in 2 hour Urine
Short Name: PYD/Creat 2h Ur
Display Name: Pyridinoline/Creatinine (2H U) [Mass ratio]
Consumer Name Alpha Get Info: Pyridinoline/Creatinine, Urine

Part Model Get Info

Component
Pyridinoline/Creatinine
LP286957-8
- Analyte
  Pyridinoline/Creatinine
  LP286957-8
  - Component Numerator
    Pyridinoline
    LP14914-3
    - Component Numerator Core
      Pyridinoline
      LP14914-3
    - Component Numerator Core Suffix
      NULL
  - Component Denominator
    Creatinine
    LP32035-5
    - Component Denominator Core
      Creatinine
      LP32035-5
    - Component Denominator Core Suffix
      NULL
- Challenge
  NULL
- Adjustment
  NULL
- Count
  NULL
Property
MRto
LP6834-8
Time
2H
LP6929-6
- Time Core
  2H
  LP6929-6
- Time Modifier
  NULL
System
Urine
LP7681-2
- System Core
  Urine
  LP7681-2
- Super System
  NULL
Scale
Qn
LP7753-9
Method
NULL

Basic Attributes

Class: CHEM
Type: Laboratory
First Released: Version 1.0k
Last Updated: Version 2.73 (MIN)
Order vs. Observation: Both
Common Test Rank Get Info: 19031

Member of these Groups Get Info

LOINC Group	Group Name
LG34792-8	Pyridinoline/Creatinine\|MRto\|Urine

Language Variants Get Info

Tag	Language	Translation
cs-CZ	Czech (Czechia)	Pyridinolin/kreatinin:Hmotnostní poměr:2 hodiny:Moč:Kvantitativní:
el-GR	Greek (Greece)	Πυριδινολίνη/Κρεατινίνη:MRto:2H:Ούρα:Qn: Synonyms: 2H CHEM MRto Qn Κρεατινίνη Ούρα Πυριδινολίνη
es-AR	Spanish (Argentina)	piridinolina/creatinina:relación de concentración de masa:2 horas:orina:cuantitativo:
es-ES	Spanish (Spain)	Piridinolina/Creatinina:Relacion de Masa:2 Horas:Orina:Qn: Synonyms: Cuantitativo
es-MX	Spanish (Mexico)	Piridinolina / Creatinina:Relación de masa:2H:Orina:Cuantitativo:
et-EE	Estonian (Estonia)	Püridinoliin/kreatiniin:MRto:2 tunni:U:Qn: Synonyms: Kvantitatiivne Uriin
fr-CA	French (Canada)	Pyridinoline/Créatinine:Ratio de masse:2 h:Urine:Quantitatif:
fr-BE	French (Belgium)	Pyridinoline/Créatinine:Ratio de masse:2 h:Urine:Quantitatif: Synonyms: Rapport de masse
fr-FR	French (France)	Pyridinoline/créatinine:Masse ratio:02H:Urine:Numérique:
it-IT	Italian (Italy)	Piridinolina/Creatinina:MRto:2h:Urine:Qn: Synonyms: 2 Ore Chimica Rapporto di Massa
ko-KR	Korean (Korea, Republic Of)	피리디놀린/크레아티닌:질량농도비:2시간:뇨:정량:
nl-NL	Dutch (Netherlands)	pyridinoline/creatinine:massaverhouding:2 uur:urine:kwantitatief: Synonyms: 2U kreatinine
pt-BR	Portuguese (Brazil)	Piridinolina/Creatinina:MCrto:2H:Urina:Qn: Synonyms: ; PYD; Pyr; Pyridinium collagen crosslinks; Creat; CR; mRto; Mass concentration ratio; 2 hours; 120 minutes; 120 min; 120min; 2HR; Ur; UR; Urn; UA; Quantitative; QNT; Quant; Quan; Chemistry; UCr
ru-RU	Russian (Russian Federation)	Пиридинолин/Креатинин:МассОтн:2 часа:Моча:Колич: Synonyms: Количественный Масс отношение
tr-TR	Turkish (Turkey)	Piridinolin/Kreatinin:KütlOr:2Sa:İdrar:Kant:
zh-CN	Chinese (China)	吡啶啉/肌酐:质量比率:2小时:尿液:定量型: Synonyms: 120分;120分钟;2.0小时;两小时;二小时 CR;Creat;肌氨酸酐;肌酸内酰胺;肌酸酐 UCr 化学;化学检验项目;化学检验项目类;化学类;化学试验;非刺激耐受型化学检验项目;非刺激耐受型化学检验项目类;非刺激耐受型化学试验;非刺激耐受型化学试验类可用数量表示的;定量性;数值型;数量型;连续数值型标尺吡啶诺林;PYD;Pyr;吡啶醚;吡啶酚尿;小便;下泉尿液肌酐尿液肌酸酐尿肌酸酐来自于同一体系的两种分析物的质量之比;质量比肌酸内酰胺

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LOINC Copyright

Copyright © Regenstrief Institute, Inc. All Rights Reserved. To the extent included herein, the LOINC table and LOINC codes are copyright © Regenstrief Institute, Inc. and the Logical Observation Identifiers Names and Codes (LOINC) Committee. See https://loinc.org/license for the full LOINC copyright and license.