13820-6

Urate/Creatinine [Mass Ratio] in 24 hour Urine

Active

Part Descriptions

LP15935-7   Urate
Uric acid (urate) is a product of the metabolic breakdown of purine nucleotides. In humans, about 70% of daily uric acid disposal occurs via the kidneys.

Elevated levels of uric acid, or hyperuricemia, may be due to genetic inheritance or diet. Excess serum levels of uric acid can lead to a type of arthritis known as gout, kidney stones, cardiovascular disease, Type 2 diabetes, and metabolic syndrome. Lesch-Nyhan syndrome (LNS), an extremely rare inherited disorder, is also associated with very high serum uric acid levels. Spasticity, involuntary movement and cognitive retardation as well as manifestations of gout are seen in cases of this syndrome. LNS is due to mutations in the HPRT1 gene. To date (2012), mutations in nine other genes have been linked to the excretion of uric acid by the kidneys: SLC2A9; ABCG2; SLC17A1; SLC22A11; SLC22A12; SLC16A9; GCKR; LRRC16A; and PDZK1.

Decreased levels of uric acid, known as hypouricemia, can have numerous causes, including low dietary zinc or iron intake. Hypouricemia has been associated with multiple sclerosis (MS). Copyright Text is available under the Creative Commons Attribution/Share-Alike License. See http://creativecommons.org/licenses/by-sa/3.0/ for details. Source: Wikipedia, Urate (Wikipedia)

LP32035-5   Creatinine
Creatinine or creatine anhydride, is a breakdown product of creatine phosphate in muscle. The loss of water molecule from creatine results in the formation of creatinine. It is transferred to the kidneys by blood plasma, whereupon it is eliminated by glomular filtration and partial tubular excretion. Creatinine is usually produced at a fairly constant rate and measuring its serum level is a simple test. A rise in blood creatinine levels is observed only with marked damage to functioning nephrons; therefore this test is not suitable for detecting early kidney disease. Creatine and creatinine are metabolized in the kidneys, muscle, liver and pancreas. Copyright Copyright ©2005-2009 Genome Alberta (Reference to original publication: Wishart DS, Knox C, Guo AC, et al. HMDB: a knowledgebase for the human metabolome. Nucleic Acids Res. 2009 37(Database issue):D603-610.) Source: Human Metabolome Database, Creatinine

Fully-Specified Name

Component

Urate/Creatinine

Property

MRto

Time

24H

System

Urine

Scale

Qn

Method

Additional Names

Short Name

Urate/Creat 24h Ur

Display Name

Urate/Creatinine (24H U) [Mass ratio]

Consumer Name Alpha Get Info

Urate/Creatinine, Urine

Basic Attributes

Class

CHEM

Type

Laboratory

First Released

Version 1.0k

Last Updated

Version 2.73

Order vs. Observation

Both

Common Test Rank Get Info

10126

Member of these Groups Get Info

Language Variants Get Info

Related Names

• 1 day
• 24 hours
• 24HR
• Chemistry
• CR
• Crea
• Creat
• Kidney
• Mass concentration ratio
• Mass ratio
• MCRto
• Nephrology
• QNT
• Quan
• Quant
• Quantitative
• Renal
• UA
• UCr
• UR
• Urates
• Uric acid
• Urn

Example Units

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CodeSystem lookup

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