Version 2.77

Part Description

LP16650-1   Histoplasma capsulatum
Histoplasmosis capsulatum is a dimorphic fungal pathogen with filamentous or yeast forms,depending on nutritional factors and temperature.The M antigen is a well-known glycoprotein used as a diagnostic antigen for acute histoplasmosis as it induces the first precipitins during disease. Monoclonal antibodies (mAbs) to the M antigen have been found to modify the pathogenesis of histoplasmosis.Given the shortcomings of current therapies, the administration of mAbs is being investigated. PMID: 22347215 The H band is less commonly seen than the M band and is indicative of chronic or severe acute infections with H capsulatum.

H. capsulatum is found in nature primarily as a saprophytic mold. The mold form is comprised of hyaline septate hyphae, which produce two different asexual reproduction structures, macroconidia and microconidia. The micronidia are believed to be responsible for disease propagation since their 2-6 µm size is well suited for disposition into the distal alveoli. Infection is typically acquired through inhalation of fungal propagules upon disturbances of contaminated soil or excreta. Environmental and genetic factors influence disease manifestations which can range from asymptomatic or mild influenza-like disease to a disseminated sepsis form. Manifestations depend on the magnitude of exposure, the host's immunological status and the virulence of the infective strain. Reactivation of latent infection can result in significant disease, particularly for immunosuppressed individuals. Despite the availability of potent antifungal drugs, nearly one in ten patients hospitalized with histoplasmosis dies. PMID: 17223625 Source: Regenstrief LOINC

Fully-Specified Name

Component
Histoplasma capsulatum Ag
Property
ACnc
Time
Pt
System
Urine
Scale
Qn
Method
IA

Additional Names

Short Name
H capsul Ag Ur IA-aCnc
Display Name
H. capsulatum Ag IA Qn (U)
Consumer Name Alpha Get Info
Histoplasma capsulatum antigen, Urine

Basic Attributes

Class
MICRO
Type
Laboratory
First Released
Version 1.0k
Last Updated
Version 2.73
Change Reason
The EIA method, which was always intended to cover more than just enzyme-linked immunoassay and whose display name for the long common name has always been Immunoassay, was renamed IA in order to eliminate ambiguity about whether the method has a broader meaning than just enzyme-linked immunoassay. Likewise, EIA.rapid was renamed IA.rapid. These changes were approved by the Laboratory LOINC Committee in June 2016.
Order vs. Observation
Both
Common Test Rank Get Info
4354

Member of these Groups Get Info

LOINC Group Group Name
LG34194-7 Histoplasma capsulatum Ag|ACnc|Sys:ANYGU
LG34716-7 Histoplasma capsulatum Ag|ACnc|Urine

Language Variants Get Info

Tag Language Translation
es-AR Spanish (Argentina) [antígeno de] Histoplasma capsulatum [Ag]:concentración arbitraria:punto en el tiempo:orina:cuantitativo:enzimoinmunoanálisis
es-ES Spanish (Spain) Histoplasma capsulatum Antígeno:Concentración arbitraria:Punto temporal:Orina:Qn:IA
Synonyms: Cuantitativo
es-MX Spanish (Mexico) Histoplasma capsulatum Ag:Concentración arbitraria:Punto temporal:Orina:Cuantitativo:Inmunoensayo
et-EE Estonian (Estonia) Histoplasma capsulatum antigeen:Acnc:Pt:U:Qn:IA
Synonyms: Juhuslik Kvantitatiivne Uriin
fr-CA French (Canada) Histoplasma capsulatum , Ag:Concentration arbitraire:Temps ponctuel:Urine:Quantitatif:IA
fr-FR French (France) Histoplasma capsulatum Ag:Arbitraire/Volume:Ponctuel:Urine:Numérique:Immunoanalyse
fr-BE French (Belgium) Histoplasma capsulatum Ag:Concentration arbitraire:Temps ponctuel:Urine:Quantitatif:IA
Synonyms: Antigène
it-IT Italian (Italy) Histoplasma capsulatum , Ag:ACnc:Pt:Urine:Qn:IA
Synonyms: Concentrazione Arbitraria Immunoassay Microbiologia Punto nel tempo (episodio)
ko-KR Korean (Korea, Republic Of) 히스토플라스마 캡슐라툼 항원:임의농도:검사시점:뇨:정량:효소면역측정법
nl-NL Dutch (Netherlands) Histoplasma capsulatum Ag:eenheid/volume:moment:urine:kwantitatief:immunoassay
Synonyms: antigeen IA
pt-BR Portuguese (Brazil) Histoplasma capsulatum Ag:ACnc:Pt:Urina:Qn:Imunoensaio
Synonyms: ; H capsul; H capsulatum; H farciminosum; Histoplasma farciminosum; Arbitrary concentration; Point in time; Random; Ur; UR; Urn; UA; Quantitative; QNT; Quant; Quan; Enzyme immunoassay; ELISA; MEIA; SUDS; ELFA; IAA; Antigen; Antigens; Histo; Histopl; Histoplasmos; Histoplasmosis; Microbiology
ru-RU Russian (Russian Federation) Histoplasma capsulatum Аг:ПроизвКонц:ТчкВрм:Моча:Колич:IA
Synonyms: Количественный Произвольная концентрация Точка во времени;Момент
tr-TR Turkish (Turkey) Histoplazma Kapsulatum Ag:SçKons:Zmlı:İdrar:Kant:İA
Synonyms: Antijen İmmünölçüm, immünoassay
zh-CN Chinese (China) 荚膜组织胞浆菌 抗原:任意型浓度:时间点:尿液:定量型:免疫测定法
Synonyms: Ag 任意型浓度(单位体积);任意浓度;单位体积的任意单位数;人工型浓度 免疫测定;免疫分析法;免疫检定法;免疫检定;免疫试验;酶免疫测定法;酶免疫测定;酶免疫分析法;酶免疫检定法;酶免疫检定;酶免疫试验 可用数量表示的;定量性;数值型;数量型;连续数值型标尺 尿;小便;下泉 微生物学;微生物学试验;微生物学试验(培养、DNA、抗原及抗体) 时刻;随机;随意;瞬间 皮疽组织胞浆菌 Ag 皮疽组织胞浆菌;美洲型组织胞浆菌;鼻疽性组织浆菌 皮疽组织胞浆菌抗原 组织胞浆菌属 组织胞浆菌病 美洲型组织胞浆菌 Ag 美洲型组织胞浆菌抗原 荚膜组织胞浆菌 Ag 鼻疽性组织浆菌 Ag 鼻疽性组织浆菌抗原

Example Units

Unit Source
[arb'U]/mL Example UCUM Units

LOINC Terminology Service (API) using HL7® FHIR® Get Info

CodeSystem lookup
https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=13971-7