15499-7

Pseudorabies virus neutralizing antibody [Titer] in Serum by Neutralization test

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Part Descriptions

LP14279-1 Pseudorabies virus
Pseudorabies virus (PRV) is an endemic disease in swine. PRV is also known as suid herpesvirus 1 or Aujeszky's disease virus. The virus is spread through contact with the saliva and nasal secretions of infected swine. Secondary hosts of pseudorabies includes dogs, cats, cattle, rats, and horses (via direct contact with swine). Symptoms of infection are similar to rabies in dogs. A swine vaccine for pseudorabies is available. Source: Regenstrief LOINC

LP207365-0 Ab.Neut
Neutralizing antibodies are antibodies that interfere with the interaction between the virus and its host cell receptor, therefore preventing infectivity. Neutralizing antibodies can be detected using a traditional VNT or other methods such as pseudovirus VNT and surrogate VNT. VNT and pseudovirus VNT use live virus (the actual virus or a recombinant virus that incorporates the viral antigen of interest, respectively) and cell culture to assess the virus-host interaction and whether neutralizing antibodies are present that block that interaction. Surrogate VNT (sVNT) does not use live virus but rather uses purified viral antigen and host cell receptor protein to mimic the same interaction. The sVNT method is currently (2021) represented in LOINC as IA, because it is an immunoassay-based method. Source: Regenstrief LOINC

LP6416-4 Neut
In LOINC, the Method "Neut" represents the virus neutralization test (VNT), also called conventional VNT, which is a specific laboratory method that is used primarily for identifying whether neutralizing antibodies for the virus of interest are present in the patient sample. The VNT involves incubating patient serum with the virus of interest, and then inoculating onto cell culture. If neutralizing antibodies are present and the virus is neutralized, the cells will not be infected. If neutralizing antibodies are not present, the virus will infect the cells in the cell culture. PMID: 32170698 This method can also be used to identify specific virus serotypes or strains, by performing separate tests in which serum is incubated with each of the specific virus serotypes or strains of interest. PMID: 169804 Source: Regenstrief LOINC

LOINC Names Get Info

Fully-Specified Name: Pseudorabies virus Ab.Neut:Titr:Pt:Ser:SemiQn:Neut
Long Common Name: Pseudorabies virus neutralizing antibody [Titer] in Serum by Neutralization test
Short Name: PRV NAb Titr Ser Nt
Display Name: Pseudorabies virus neut ab Neut test (S) [Titer]
Consumer Name Alpha Get Info: Pseudorabies virus neutralizing antibody, Blood

Part Model Get Info

Component
Pseudorabies virus Ab.Neut
LP430460-8
- Analyte
  Pseudorabies virus Ab.Neut
  LP430460-8
  - Component Numerator
    Pseudorabies virus Ab.Neut
    LP430460-8
    - Component Numerator Core
      Pseudorabies virus
      LP14279-1
    - Component Numerator Core Suffix
      Ab.Neut
      LP207365-0
  - Component Denominator
    NULL
    - Component Denominator Core
      NULL
    - Component Denominator Core Suffix
      NULL
- Challenge
  NULL
- Adjustment
  NULL
- Count
  NULL
Property
Titr
LP6881-9
Time
Pt
LP6960-1
- Time Core
  Pt
  LP6960-1
- Time Modifier
  NULL
System
Ser
LP7567-3
- System Core
  Ser
  LP7567-3
- Super System
  NULL
Scale
SemiQn
LP436123-6
Method
Neut
LP6416-4

Basic Attributes

Class: MICRO
Type: Laboratory
First Released: Version 1.0k
Last Updated: Version 2.75 (MAJ)
Change Reason: Release 2.72: COMPONENT: Updated "Ab" to "Ab.Neut" since this test is detecting neutralizing antibodies.;
Order vs. Observation: Both

Language Variants Get Info

Tag	Language	Translation
cs-CZ	Czech (Czechia)	Virus pseudovztekliny Ab.neutralizační:Arbitrární koncentrace (titr):Časový bod:Sérum:Semikvantitativní:Neutralizační test
el-GR	Greek (Greece)	Ιός ψευδολύσσας Ab.Neut:Titr:Pt:Ορός:Ημιποσοτική:Ουδετερόφιλα Synonyms: Ab.Neut MICRO Pt Titr Αντίσωμα Ημιποσοτική Ιός Ιός ψευδολύσσας Ορός Ουδετερόφιλα
es-AR	Spanish (Argentina)	[anticuerpo anti - ] virus de la seudorrabia [Ac]:factor de dilución (titulación):punto en el tiempo:suero:cuantitativo:neutralización
es-ES	Spanish (Spain)	Virus de Pseudorrabia (Herpes Virus Porcino 1) Anticuerpos antineutrófilos:Titulo / Factor de dilución:Punto temporal:Suero:Semicuantitativo:Prueba de neutralización Synonyms: Semicuantitativo
es-MX	Spanish (Mexico)	Virus de la pseudorrabia Ab:Título:Punto temporal:Suero:Cuantitativo:Prueba de neutralización
fr-FR	French (France)	Virus pseudorabique Ac neutralisant:Titre:Ponctuel:Sérum:Semi-Quantitatif:Neutralisation
fr-CA	French (Canada)	Virus de la pseudorage Ac.neut:Titre:Temps ponctuel:Sérum:SemiQn:Test de neutralisation
it-IT	Italian (Italy)	Pseudorabbia, virus Ab.Neut:Titr:Pt:Siero:SemiQn:Neut Synonyms: anticorpo Microbiologia Punto nel tempo (episodio) Siero Test di neutralizzazione Titolo Virus della pseudorabbia
ko-KR	Korean (Korea, Republic Of)	거짓미친개병 바이러스 항체:역가:검사시점:혈청:정량:중화
nl-NL	Dutch (Netherlands)	Pseudorabies virus As.neutraliserend:titer:moment:serum:semikwantitatief:neutralisatietest Synonyms: antistof; antilichaam
pl-PL	Polish (Poland)	Wirus wścieklizny rzekomej Ab.Neutralizujące:miano:punkt w czasie:surowica:półilościowy:test neutralizacji Synonyms: Przeciwciała do wirusa wścieklizny rzekomej Przeciwciała neutralizujące do wirusa wścieklizny rzekomej
pt-BR	Portuguese (Brazil)	Pseudoraiva vírus Ac:Título:Pt:Soro:Qn:Teste de neutralização Synonyms: ; PRV; Aujeszky's disease; Porcine herpes virus 1; PHV1; Suid herpesvirus-1; SHV-1; Aujezskys disease; Alpha-herpesvirus; Dilution factor; Titer; Titre; Ttr; Titered; Point in time; Random; Serum; SR; Quantitative; QNT; Quant; Quan; Nt; NT; Neutralization test; Antibodies; Autoantibody; Antibody; Autoantibodies; Antby; Acy; Anti; Microbiology
zh-CN	Chinese (China)	伪狂犬病病毒抗体.中和:滴定度:时间点:血清:半定量型:中和试验 Synonyms: Ab;自身抗体 Alpha-疱疹病毒 Ab Alpha-疱疹病毒;Aujeszkys 病;Aujezskys 病;PRV;α-疱疹病毒;传染性延髓麻痹;传染性延髓麻痹病毒;伪狂犬病;奇痒症;奇痒症病毒;奥叶兹基氏病;奥叶兹基氏病病毒;猪疱疹病毒 1 型;猪疱疹病毒 I 型;猪疱疹病毒Ⅰ型;甲疱疹病毒 Alpha-疱疹病毒抗体 PRV Ab PRV 抗体 α-疱疹病毒 Ab α-疱疹病毒抗体中和试验;中和抗体;中和传染性延髓麻痹病毒 Ab 传染性延髓麻痹病毒抗体传染毒;传染毒素;滤过性病原体;病毒类;过滤性病原体伪狂犬病病毒 Ab 奇痒症病毒 Ab 奇痒症病毒抗体奥叶兹基氏病病毒 Ab 奥叶兹基氏病病毒抗体微生物学;微生物学试验;微生物学试验（培养、DNA、抗原及抗体）效价;滴定浓度;滴定率;滴定量;滴度;稀释倍数;稀释因子;稀释系数时刻;随机;随意;瞬间猪疱疹病毒 1 型 Ab 猪疱疹病毒 1 型抗体猪疱疹病毒 I 型 Ab 猪疱疹病毒 I 型抗体猪疱疹病毒Ⅰ型 Ab 猪疱疹病毒Ⅰ型抗体

Example Units

Unit	Source
{titer}	Example UCUM Units

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LOINC Copyright

Copyright © Regenstrief Institute, Inc. All Rights Reserved. To the extent included herein, the LOINC table and LOINC codes are copyright © Regenstrief Institute, Inc. and the Logical Observation Identifiers Names and Codes (LOINC) Committee. See https://loinc.org/license for the full LOINC copyright and license.