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Status Information

Status
DISCOURAGED
Comment
Most laboratories report this in moles. Double check with your lab for reporting units.

Part Description

LP15301-2   3-Hydroxyisovalerate
3-Hydroxyisovaleric acid is a normal human metabolite excreted in the urine. Elevated levels of this compound are found in several inherited disorders such as Dihydrolipoamide dehydrogenase Deficiency, 3-Methylcrotonyl-CoA carboxylase 1 deficiency, 3-Hydroxy-3-methylglutaryl-CoA lyase deficiency (3-hydroxy-3-methylglutaryl -CoA lyase Deficiency, Biotinidase deficiency multiple carboxylase deficiency late-onset , Late onset multiple carboxylase deficiency, HolMcarboxylase synthetase deficiency, 3-Methylcrotonyl-CoA carboxylase 2 deficiency. 3-Hydroxyisovaleric acid is also elevated in smokers, in subjects undergoing long-term anticonvulsant therapy with carbamazepine and/or phenytoin. These levels are elevated due to impairment of renal reclamation of biotin. Levels may also be increased from prolonged consumption of raw egg-whites PMID: 16895887, PMID: 9523856, PMID: 15447901, PMID: 9176832, [OMIM: 210210], [OMIM: 253270], [OMIM: 600529], [OMIM: 253260], [OMIM: 246450], [OMIM: 210200], [OMIM: 238331] Copyright Copyright ©2005-2009 Genome Alberta (Reference to original publication: Wishart DS, Knox C, Guo AC, et al. HMDB: a knowledgebase for the human metabolome. Nucleic Acids Res. 2009 37(Database issue):D603-610.) Source: Human Metabolome Database, Human Metabolome Database

LOINC Names Get Info

Fully-Specified Name
3-Hydroxyisovalerate:MCnc:Pt:Urine:Qn:
Long Common Name
3-Hydroxyisovalerate [Mass/volume] in Urine
Short Name
3OH-Isovalerate Ur-mCnc
Display Name
3-Hydroxyisovalerate (U) [Mass/Vol]
Consumer Name Alpha Get Info
3-Hydroxyisovalerate, Urine

Part Model Get Info

  • Component
    3-Hydroxyisovalerate
    LP15301-2
    • Analyte
      3-Hydroxyisovalerate
      LP15301-2
      • Component Numerator
        3-Hydroxyisovalerate
        LP15301-2
        • Component Numerator Core
          3-Hydroxyisovalerate
          LP15301-2
        • Component Numerator Core Suffix
          NULL
           
      • Component Denominator
        NULL
         
        • Component Denominator Core
          NULL
           
        • Component Denominator Core Suffix
          NULL
           
    • Challenge
      NULL
       
    • Adjustment
      NULL
       
    • Count
      NULL
       
  • Property
    MCnc
    LP6827-2
  • Time
    Pt
    LP6960-1
  • System
    Urine
    LP7681-2
    • System Core
      Urine
      LP7681-2
    • Super System
      NULL
       
  • Scale
    Qn
    LP7753-9
  • Method
    NULL
     

Basic Attributes

Class
CHEM
Type
Laboratory
First Released
Version 1.0
Last Updated
Version 2.42 (MIN)
Order vs. Observation
Observation

Language Variants Get Info

TagLanguageTranslation
cs-CZCzech (Czechia)3-hydroxyizovalerát:Hmotnostní koncentrace:Časový bod:Moč:Kvantitativní:
el-GRGreek (Greece)3-υδροξυϊσοβαλεριανικό:MCnc:Pt:Ούρα:Qn:
Synonyms: 3-υδροξυϊσοβαλεριανικό CHEM MCnc Pt Qn Ούρα
es-ARSpanish (Argentina)3-hidroxiisovalerato:concentración de masa:punto en el tiempo:orina:cuantitativo:
es-ESSpanish (Spain)3-Hidroxiisovalerato:Concentración de masa:Punto temporal:Orina:Qn:
Synonyms: Cuantitativo
es-MXSpanish (Mexico)3-hidroxiisovalerato:Concentración de masa:Punto temporal:Orina:Cuantitativo:
et-EEEstonian (Estonia)3-hüdroksüisovaleraat:MCnc:Pt:U:Qn:
Synonyms: Juhuslik Kvantitatiivne Uriin
fr-CAFrench (Canada)3-hydroxyisovalérate:Concentration de masse:Temps ponctuel:Urine:Quantitatif:
fr-BEFrench (Belgium)3-hydroxyisovalérate:Concentration de masse:Temps ponctuel:Urine:Quantitatif:
fr-FRFrench (France)3-hydroxyisovalérate:Masse/Volume:Ponctuel:Urine:Numérique:
it-ITItalian (Italy)3-Idrossiisovalerato:MCnc:Pt:Urine:Qn:
Synonyms: Chimica Concentrazione di Massa Punto nel tempo (episodio)
ko-KRKorean (Korea, Republic Of)3-하이드록시이소발레레이트:질량농도:검사시점:뇨:정량:
nl-NLDutch (Netherlands)3-hydroxyisovaleraat:massa/volume:moment:urine:kwantitatief:
pl-PLPolish (Poland)3-Hydroksyizowalerian:stężenie masowe:punkt w czasie:mocz:ilościowy:
pt-BRPortuguese (Brazil)3-Hidroxiisovalerato:MCnc:Pt:Urina:Qn:
Synonyms: ; 3OH-Isovalerate; 3-hydroxy-isovalerate; 3-HIA; 3-hydroxyisovaleric acid; Mass concentration; Level; Point in time; Random; Ur; UR; Urn; UA; Quantitative; QNT; Quant; Quan; III; Chemistry
ru-RURussian (Russian Federation)3-Гидроксиизовалерат:МассКонц:ТчкВрм:Моча:Колич:
Synonyms: Количественный Массовая концентрация Точка во времени;Момент
tr-TRTurkish (Turkey)3-Hidroksiizovalerat:KütlKons:Zmlı:İdrar:Kant:
zh-CNChinese (China)3-羟基异戊酸:质量浓度:时间点:尿液:定量型:
Synonyms: 3-HIA;3OH-异戊酸;3-羟基-异戊酸 Ⅲ III 三 化学;化学检验项目;化学检验项目类;化学类;化学试验;非刺激耐受型化学检验项目;非刺激耐受型化学检验项目类;非刺激耐受型化学试验;非刺激耐受型化学试验类 叁 可用数量表示的;定量性;数值型;数量型;连续数值型标尺 尿;小便;下泉 时刻;随机;随意;瞬间 水平;浓度;质量浓度(单位体积)

LOINC Terminology Service (API) using HL7® FHIR® Get Info

CodeSystem lookup
https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=1683-2