Version 2.80

Part Description

LP36918-8   21-hydroxylase Ab
Adrenal enzyme steroid 21-hydroxylase (P450c21, CYP21A2) lesions lead to faulty synthesis of adrenal cortisol with frequent deficiency of aldosterone. PMID: 8478006 Cytochrome P450c21 is the essential enzyme in the synthesis of cortisol. It converts progesterone and 17 alpha-hydroxyprogesterone to 11-deoxycorticosterone and 11-doxycortisol, respectively, which in turn are needed to synthesize aldosterone and cortisol. There are two CYP21 genes on chromosome 6 that are arranged together. One that is a pseudogene (CYP21A) and one that is a functional gene (CYP21B). It is proposed that gene crossover between CYP21A and CYP21B may be one of the causes of P450c21 deficiency that ultimately leads to congenital adrenal hyperplasia. One in 10,000 births are found to have P450c21 deficiency and is the primary cause of adrenal hyperplasia. PMID: 2233746[http://www.sciencedirect.com/science/article/pii/S0006291X06005924) Source: Regenstrief LOINC

Fully-Specified Name

Component
21-Hydroxylase Ab
Property
ACnc
Time
Pt
System
Ser
Scale
Qn
Method

Additional Names

Long Common Name
21-Hydroxylase Ab [Units/volume] in Serum
Short Name
21Hydroxylase Ab Ser-aCnc
Display Name
21-Hydroxylase Ab Qn (S)
Consumer Name Alpha Get Info
21-Hydroxylase antibody, Blood

Basic Attributes

Class
SERO
Type
Laboratory
First Released
Version 1.0l
Last Updated
Version 2.73 (MIN)
Order vs. Observation
Both
Common Test Rank Get Info
3568

Language Variants Get Info

Tag Language Translation
de-DE German (Germany) Steroid-21-Hydroxylase Ak:Arbiträre Konzentration:Zeitpunkt:Serum:Quantitativ:
Synonyms: CYP21A2; Steroid-21-Hydroxylase
de-AT German (Austria) Synonyms: 21-Hydroxylase AK
el-GR Greek (Greece) 21-υδροξυλάση Αντίσωμα:ACnc:Pt:Ορός:Qn:
Synonyms: ACnc
es-ES Spanish (Spain) 21- Hidroxilasa Anticuerpos:Concentración arbitraria:Punto temporal:Suero:Qn:
Synonyms: Cuantitativo
es-MX Spanish (Mexico) 21-hidroxilasa Ab:Concentración arbitraria:Punto temporal:Suero:Cuantitativo:
es-AR Spanish (Argentina) [anticuerpo anti - ] 21-hidroxilasa:concentración arbitraria:punto en el tiempo:suero:cuantitativo:
et-EE Estonian (Estonia) 21-hüdroksülaasi vastased antikehad:Acnc:Pt:S:Qn:
Synonyms: Juhuslik Kvantitatiivne Seerum
fr-CA French (Canada) 21-hydroxylase, Ac:Concentration arbitraire:Temps ponctuel:Sérum:Quantitatif:
fr-FR French (France) 21-hydroxylase anticorps:Arbitraire/Volume:Ponctuel:Sérum:Numérique:
fr-BE French (Belgium) 21-hydroxylase Ac:Concentration arbitraire:Temps ponctuel:Sérum:Quantitatif:
Synonyms: Anticorps
it-IT Italian (Italy) 21-Idrossilasi Ab:ACnc:Pt:Siero:Qn:
Synonyms: anticorpo Concentrazione Arbitraria Punto nel tempo (episodio) Siero Sierologia (anticorpi e la maggior parte degli ant
ko-KR Korean (Korea, Republic Of) 21-수산화효소 항체:임의농도:검사시점:혈청:정량:
nl-NL Dutch (Netherlands) 21-hydroxylase As:eenheid/volume:moment:serum:kwantitatief:
Synonyms: antistof; antilichaam
pt-BR Portuguese (Brazil) 21-Hidroxilase Ac:ACnc:Pt:Soro:Qn:
Synonyms: ; 21Hydroxylase; Steroid 21-monooxygenase; Steroid 21-hydroxylase; Arbitrary concentration; Point in time; Random; Serum; SR; Quantitative; QNT; Quant; Quan; Antibodies; Autoantibody; Antibody; Autoantibodies; Antby; Acy; Anti; Hydroxyl; Serology
ru-RU Russian (Russian Federation) 21-Гидроксилаза Ат:ПроизвКонц:ТчкВрм:Сыв:Колич:
Synonyms: Антитело Количественный Произвольная концентрация Сыворотка Точка во времени;Момент
tr-TR Turkish (Turkey) 21-Hidroksilaz Ab:SçKons:Zmlı:Ser:Kant:
zh-CN Chinese (China) 21-羟化酶 抗体:任意型浓度:时间点:血清:定量型:
Synonyms: 21-羟化酶 Ab Ab;自身抗体 任意型浓度(单位体积);任意浓度;单位体积的任意单位数;人工型浓度 可用数量表示的;定量性;数值型;数量型;连续数值型标尺 时刻;随机;随意;瞬间 氢氧酶 类固醇 21-单加氧酶 Ab 类固醇 21-单加氧酶;类固醇 21-单氧酶;类固醇 21-羟化酶 类固醇 21-单加氧酶抗体 类固醇 21-单氧酶 Ab 类固醇 21-单氧酶抗体 类固醇 21-羟化酶 Ab 类固醇 21-羟化酶抗体 血清;血清学;血清学检验项目;血清学检验项目 (非微生物学);血清学检验项目（非微生物学）;血清学检验项目类;血清学检验项目类 (非微生物学);血清学类;血清学类检验项目;血清学类检验项目 (非微生物学);血清学类试验;血清学类试验 (非微生物学);血清学试验;血清学试验 (非微生物学);血清学试验（非微生物学）;血清学试验类 (非微生物学);血清类

Example Units

Unit Source
units/mL REGENSTRIEF
[arb'U]/mL Example UCUM Units

LOINC Terminology Service (API) using HL7® FHIR® Get Info

CodeSystem lookup
https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=17781-6