19182-5

Cytokeratin 19 [Units/volume] in Serum or Plasma

Active

Part Description

LP19423-0 Cytokeratin 19
Keratin, type I cytoskeletal 19 also known as cytokeratin-19 (CK-19) or keratin-19 (K19) is a protein that in humans is encoded by the KRT19 gene.

Due to its high sensitivity, KRT19 is the most used marker for the RT-PCR-mediated detection of tumor cells disseminated in lymph nodes, peripheral blood, and bone marrow of breast cancer patients. Depending on the assays, KRT19 has been shown to be both a specific and a non-specific marker. False positivity in such KRT19 RT-PCR studies include: illegitimate transcription (expression of small amounts of KRT19 mRNA by tissues in which it has no real physiological role), haematological disorders (KRT19 induction in peripheral blood cells by cytokines and growth factors, which circulate at higher concentrations in inflammatory conditions and neutropenia), the presence of pseudogenes (two KRT19 pseudogenes, KRT19a and KRT19b, have been identified, which have significant sequence homology to KRT19 mRNA. Subsequently, attempts to detect the expression of the authentic KRT19 may result in the detection of either or both of these pseudogenes), sample contamination (introduction of contaminating epithelial cells during peripheral blood sampling for subsequent RT-PCR analysis).

Keratin 19 is often used together with keratin 8 and keratin 18 to differentiate cells of epithelial origin from hematopoietic cells in tests that enumerate circulating tumor cells in blood. Copyright Text is available under the Creative Commons Attribution/Share-Alike License. See http://creativecommons.org/licenses/by-sa/3.0/ for details. Source: Wikipedia, Wikipedia

LOINC Names Get Info

Fully-Specified Name: Cytokeratin 19:ACnc:Pt:Ser/Plas:Qn:
Long Common Name: Cytokeratin 19 [Units/volume] in Serum or Plasma
Short Name: CK 19 SerPl-aCnc
Display Name: Cytokeratin 19 Qn
Consumer Name Alpha Get Info: Cytokeratin 19, Blood

Part Model Get Info

Component
Cytokeratin 19
LP19423-0
- Analyte
  Cytokeratin 19
  LP19423-0
  - Component Numerator
    Cytokeratin 19
    LP19423-0
    - Component Numerator Core
      Cytokeratin 19
      LP19423-0
    - Component Numerator Core Suffix
      NULL
  - Component Denominator
    NULL
    - Component Denominator Core
      NULL
    - Component Denominator Core Suffix
      NULL
- Challenge
  NULL
- Adjustment
  NULL
- Count
  NULL
Property
ACnc
LP6773-8
Time
Pt
LP6960-1
- Time Core
  Pt
  LP6960-1
- Time Modifier
  NULL
System
Ser/Plas
LP7576-4
- System Core
  Ser/Plas
  LP7576-4
- Super System
  NULL
Scale
Qn
LP7753-9
Method
NULL

Basic Attributes

Class: CHEM
Type: Laboratory
First Released: Version 1.0l
Last Updated: Version 2.68 (MIN)
Order vs. Observation: Both

Language Variants Get Info

Tag	Language	Translation
cs-CZ	Czech (Czechia)	Cytokeratin 19:Arbitrární koncentrace:Časový bod:Sérum/plazma:Kvantitativní:
de-DE	German (Germany)	Zytokeratin 19:Arbiträre Konzentration:Zeitpunkt:Serum oder Plasma:Quantitativ: Synonyms: Cyfra 21-1
el-GR	Greek (Greece)	Κυτοκερατίνη 19:ACnc:Pt:Ορός/Πλάσμα:Qn: Synonyms: ACnc CHEM Pt Qn Κυτοκερατίνη 19 Ορός Ορός/Πλάσμα Πλάσμα
es-AR	Spanish (Argentina)	citoqueratina 19:concentración arbitraria:punto en el tiempo:suero/plasma:cuantitativo:
es-ES	Spanish (Spain)	Citoqueratina 19:Concentración arbitraria:Punto temporal:Suero o Plasma:Qn: Synonyms: Cuantitativo
es-MX	Spanish (Mexico)	Citoqueratina 19:Concentración arbitraria:Punto temporal:Suero o Plasma:Cuantitativo:
et-EE	Estonian (Estonia)	Tsütokeratiin 19:Acnc:Pt:S/P:Qn: Synonyms: Juhuslik Kvantitatiivne Plasma Seerum Seerum või plasma
fr-CA	French (Canada)	Cytokératine 19:Concentration arbitraire:Temps ponctuel:Sérum/Plasma:Quantitatif:
fr-FR	French (France)	Cyfra 21:Arbitraire/Volume:Ponctuel:Sérum/Plasma:Numérique:
fr-BE	French (Belgium)	Cytokératine 19:Concentration arbitraire:Temps ponctuel:Sérum/Plasma:Quantitatif:
it-IT	Italian (Italy)	Citocheratina 19:ACnc:Pt:Siero/Plasma:Qn: Synonyms: Chimica Concentrazione Arbitraria Plasma Punto nel tempo (episodio) Siero Siero o Plasma
ko-KR	Korean (Korea, Republic Of)	사이토케라틴 19:임의농도:검사시점:혈청/혈장:정량:
nl-NL	Dutch (Netherlands)	cytokeratine 19:eenheid/volume:moment:serum of plasma:kwantitatief:
pl-PL	Polish (Poland)	Cytokeratyna 19:stężenie w jednostkach umownych:punkt w czasie:surowica lub osocze:ilościowy:
pt-BR	Portuguese (Brazil)	Citoqueratina 19:ACnc:Pt:Sor/Plas:Qn: Synonyms: ; CK 19; Cyfra 21-1; Autoimmune hepatitis; Arbitrary concentration; Point in time; Random; SerPl; SerPlas; SerP; Serum; SR; Plasma; Pl; Plsm; Quantitative; QNT; Quant; Quan; Chemistry
ru-RU	Russian (Russian Federation)	Цитокератин 19:ПроизвКонц:ТчкВрм:Сыв/Плаз:Колич: Synonyms: Количественный Плазма Произвольная концентрация Сыворотка Сыворотка или Плазма Точка во времени;Момент
tr-TR	Turkish (Turkey)	Sitokeratin 19:SçKons:Zmlı:Ser/Plaz:Kant:
zh-CN	Chinese (China)	细胞角蛋白 19:任意型浓度:时间点:血清/血浆:定量型: Synonyms: CK 19;Cyfra 21-1;细胞角蛋白-19 任意型浓度(单位体积);任意浓度;单位体积的任意单位数;人工型浓度化学;化学检验项目;化学检验项目类;化学类;化学试验;非刺激耐受型化学检验项目;非刺激耐受型化学检验项目类;非刺激耐受型化学试验;非刺激耐受型化学试验类可用数量表示的;定量性;数值型;数量型;连续数值型标尺时刻;随机;随意;瞬间自身免疫型肝炎;自身免疫性肝炎血清或血浆

Example Units

Unit	Source
[arb'U]/L	Example UCUM Units

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LOINC Copyright

Copyright © Regenstrief Institute, Inc. All Rights Reserved. To the extent included herein, the LOINC table and LOINC codes are copyright © Regenstrief Institute, Inc. and the Logical Observation Identifiers Names and Codes (LOINC) Committee. See https://loinc.org/license for the full LOINC copyright and license.