Version 2.66

2006-5Cancer Ag 125 [Presence] in Serum or PlasmaActive

Cancer Ag 125

Additional Names

Short Name
Cancer Ag125 SerPl Ql
Display Name Beta
Cancer Ag 125 Ql
Consumer Name Alpha
Cancer Ag 125, Blood

Part Description

LP14543-0   Cancer Ag 125
CA 125 is an antigenic determinant associated with a mucin-like glycoprotein, molecular weight exceeding 500,000 Daltons. This determinant is recognized by the murine monoclonal antibody OC 125, which reacts with over 80% of epithelial ovarian cancers. Elevated CA 125 levels have been reported in subjects with serous, endometrioid, clear cell, and undifferentiated ovarian carcinoma adenocarcinoma of the endometrium or fallopian tube, as well as some nongynocologic malignancies and certain nonmalignant conditions. Elevated levels also have been observed in pregnant women, most often during the first trimester. CA 125 levels may have significant value in monitoring ovarian carcinoma patients. A persistently rising CA 125 value may be associated with progressive malignant disease and poor therapeutic response. A declining CA 125 value is indicative of favorable prognosis and good response to treatment. CA 125 levels may help predict whether an invasive second-look procedure such as laparoscopy or laparotomy is required after treatment for epithelial ovarian cancer.
I.A. KOELMA, M. NAP, C.J. RODENBURG, G.J. FLEUREN (1987) The value of tumour marker CA 125 in surgical pathology
Histopathology 11 (3) , 287–294 doi:10.1111/j.1365-2559.1987.tb02633. Source: Regenstrief Institute

Basic Attributes

First Released
Version 1.0
Last Updated
Version 2.56
Change Reason
The PrThr property is used for LOINC terms whose results are reported using an ordered categorical scale, regardless of whether or not an internal threshold was used to make that determination. This change was approved by the Laboratory LOINC Committee in June 2016.
Order vs. Observation
Common US Lab Results Rank
Common SI Lab Results Rank

Reference Information

Type Source Reference
Mapping Guidance Regenstrief Help Usually reported as a quantitative test in ser/plas [LOINC: 10334-1]. Mapper’s Guide for the Top 2000 plus LOINC Laboratory Observations

Language Variants Get Info

zh-CNChinese (China)
癌抗原 125:存在情况或阈值:时间点:血清/血浆:序数型:
nl-NLDutch (Netherlands)
CA125:aanwezigheid:moment:serum of plasma:ordinaal:
et-EEEstonian (Estonia)
Kasvajaantigeen CA 125:PrThr:Pt:S/P:Ord:
fr-BEFrench (Belgium)
Ag carbohydraté 125:PrThr:Temps ponctuel:Sérum/Plasma:Ordinal:
fr-CAFrench (Canada)
Ag carbohydraté 125:Présence-Seuil:Temps ponctuel:Sérum/Plasma:Ordinal:
fr-FRFrench (France)
Cancer Ag 125:PrThr:Pt:Ser/Plas:Ord:
el-GRGreek (Greece)
Καρκινικό αντιγόνο 125:PrThr:Χρονική στιγμή:Ορός/Πλάσμα:Τακτική:
it-ITItalian (Italy)
Cancro, Ag 125:PrThr:Pt:Siero/Plasma:Ord:
ko-KRKorean (Korea, Republic of)
암 항원 125:임의농도:검사시점:혈청/혈장:순위척도:
pt-BRPortuguese (Brazil)
Câncer Ag 125:ACnc:Pt:Sor/Plas:Ord:
ru-RURussian (Russian Federation)
Раковый Аг 125:PrThr:ТчкВрм:Сыв/Плаз:Пор:
es-ARSpanish (Argentina)
antígeno 125 del cáncer:concentración arbitraria:punto en el tiempo:suero/plasma:ordinal:
es-ESSpanish (Spain)
Ag de cáncer 125:PrThr:Punto temporal:Suero o Plasma:Ord:
tr-TRTurkish (Turkey)
Kanser Ag 125:MevcEşik:Zmlı:Ser/Plaz:Srl:

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