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Part Description

LP14543-0   Cancer Ag 125
CA 125 is an antigenic determinant associated with a mucin-like glycoprotein, molecular weight exceeding 500,000 Daltons. This determinant is recognized by the murine monoclonal antibody OC 125, which reacts with over 80% of epithelial ovarian cancers. Elevated CA 125 levels have been reported in subjects with serous, endometrioid, clear cell, and undifferentiated ovarian carcinoma adenocarcinoma of the endometrium or fallopian tube, as well as some nongynocologic malignancies and certain nonmalignant conditions. Elevated levels also have been observed in pregnant women, most often during the first trimester. CA 125 levels may have significant value in monitoring ovarian carcinoma patients. A persistently rising CA 125 value may be associated with progressive malignant disease and poor therapeutic response. A declining CA 125 value is indicative of favorable prognosis and good response to treatment. CA 125 levels may help predict whether an invasive second-look procedure such as laparoscopy or laparotomy is required after treatment for epithelial ovarian cancer.
I.A. KOELMA, M. NAP, C.J. RODENBURG, G.J. FLEUREN (1987) The value of tumour marker CA 125 in surgical pathology
Histopathology 11 (3) , 287-294 doi:10.1111/j.1365-2559.1987.tb02633. Source: Regenstrief Institute

Reference Information

TypeSourceReference
Mapping GuidanceRegenstrief HelpUsually reported as a quantitative test in ser/plas LOINC 10334-1. Mapper’s Guide for the Top 2000 plus LOINC Laboratory Observations

LOINC Names Get Info

Fully-Specified Name
Cancer Ag 125:PrThr:Pt:Ser/Plas:Ord:
Long Common Name
Cancer Ag 125 [Presence] in Serum or Plasma
Short Name
Cancer Ag125 SerPl Ql
Display Name
Cancer Ag 125 Ql
Consumer Name Alpha Get Info
Cancer Ag 125, Blood

Part Model Get Info

  • Component
    Cancer Ag 125
    LP14543-0
    • Analyte
      Cancer Ag 125
      LP14543-0
      • Component Numerator
        Cancer Ag 125
        LP14543-0
        • Component Numerator Core
          Cancer Ag 125
          LP14543-0
        • Component Numerator Core Suffix
          NULL
           
      • Component Denominator
        NULL
         
        • Component Denominator Core
          NULL
           
        • Component Denominator Core Suffix
          NULL
           
    • Challenge
      NULL
       
    • Adjustment
      NULL
       
    • Count
      NULL
       
  • Property
    PrThr
    LP217195-9
  • Time
    Pt
    LP6960-1
  • System
    Ser/Plas
    LP7576-4
    • System Core
      Ser/Plas
      LP7576-4
    • Super System
      NULL
       
  • Scale
    Ord
    LP7751-3
  • Method
    NULL
     

Basic Attributes

Class
CHEM
Type
Laboratory
First Released
Version 1.0
Last Updated
Version 2.73 (MIN)
Change Reason
The PrThr property is used for LOINC terms whose results are reported using an ordered categorical scale, regardless of whether or not an internal threshold was used to make that determination. This change was approved by the Laboratory LOINC Committee in June 2016.
Order vs. Observation
Both
Common Test Rank Get Info
3593

Language Variants Get Info

TagLanguageTranslation
ar-JOArabic (Jordan)الواسم " المؤشر " " المستضد " السرطاني 125
Synonyms: المؤشر السرطاني 125
cs-CZCzech (Czechia)Cancer Ag 125:Přítomnost nebo práh:Časový bod:Sérum/plazma:Ordinální:
el-GRGreek (Greece)Καρκινικό αντιγόνο 125:PrThr:Pt:Ορός/Πλάσμα:Ord:
Synonyms: CHEM Ord PrThr Pt Καρκινικό αντιγόνο 125 Καρκίνος Ορός Ορός/Πλάσμα Πλάσμα
es-ARSpanish (Argentina)antígeno 125 del cáncer:concentración arbitraria:punto en el tiempo:suero/plasma:ordinal:
es-ESSpanish (Spain)Ag de cáncer 125:PrThr:Punto temporal:Suero o Plasma:Ord:
es-MXSpanish (Mexico)Cáncer Ag 125:Presencia o umbral:Punto temporal:Suero o Plasma:Ordinal:
et-EEEstonian (Estonia)Kasvajaantigeen CA 125:PrThr:Pt:S/P:Ord:
Synonyms: Järgarvuline Juhuslik Plasma Seerum Seerum või plasma
fr-CAFrench (Canada)Ag carbohydraté 125:Présence-Seuil:Temps ponctuel:Sérum/Plasma:Ordinal:
fr-FRFrench (France)Carbohydrate antigène 125:Présence/Seuil:Ponctuel:Sérum/Plasma:Qualitatif:
fr-BEFrench (Belgium)Ag carbohydraté 125:PrThr:Temps ponctuel:Sérum/Plasma:Ordinal:
Synonyms: Ca 125
it-ITItalian (Italy)Cancro, Ag 125:PrThr:Pt:Siero/Plasma:Ord:
Synonyms: Antigene 125 di cancro Chimica Plasma Presenza o Soglia Punto nel tempo (episodio) Siero Siero o Plasma
ko-KRKorean (Korea, Republic Of)암 항원 125:임의농도:검사시점:혈청/혈장:순위척도:
nl-NLDutch (Netherlands)CA125:aanwezigheid:moment:serum of plasma:ordinaal:
Synonyms: kanker Ag 125
pl-PLPolish (Poland)CA 125 Ag:granica wykrywalności:punkt w czasie:surowica lub osocze:uporządkowany:
Synonyms: Antygen CA 125
pt-BRPortuguese (Brazil)Câncer Ag 125:ACnc:Pt:Sor/Plas:Ord:
Synonyms: ; Cancer Ag125; OC125; CA 125; Cancer antigen 125; Arbitrary concentration; Point in time; Random; SerPl; SerPlas; SerP; Serum; SR; Plasma; Pl; Plsm; Ql; Ordinal; QL; Qualitative; Qual; Screen; Antigen; Antigens; Chemistry
ru-RURussian (Russian Federation)Раковый Аг 125:PrThr:ТчкВрм:Сыв/Плаз:Пор:
Synonyms: Плазма Порядковый Сыворотка Сыворотка или Плазма Точка во времени;Момент
tr-TRTurkish (Turkey)Kanser Ag 125:MevcEşik:Zmlı:Ser/Plaz:Srl:
Synonyms: Mevcut
zh-CNChinese (China)癌抗原 125:存在情况或阈值:时间点:血清/血浆:序数型:
Synonyms: CA CA 125;OC125;癌 Ag 125;癌抗原 125（Cancer Antigen 125，CA 125） 依次型;分类顺序型;定性的;序数型（或称等级型）;性质上的;有序型;有序性分类应答;有序性分类结果;秩次型;等级型;筛查;顺序型 化学;化学检验项目;化学检验项目类;化学类;化学试验;非刺激耐受型化学检验项目;非刺激耐受型化学检验项目类;非刺激耐受型化学试验;非刺激耐受型化学试验类 存在情况;存在;存在与否;是否存在;阈值;界值;界限;阀值;临界值;存在情况（存在、存在与否、是否存在）或阈值（界值、界限、阀值、临界值） 时刻;随机;随意;瞬间 癌 癌 Ag 癌症抗原 血清或血浆

LOINC Terminology Service (API) using HL7® FHIR® Get Info

CodeSystem lookup
https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=2006-5