Version 2.78

Part Description

LP14400-3   Hepatitis C virus
Hepatitis C virus (HCV) is a small (50 nm in size), enveloped, single-stranded, positive sense RNA virus in the genus hepacivirus, which is in the Flaviviridae family. More than 170 million people worldwide are affected by hepatitis C, and the majority of patients with acute hepatitis C develop chronic HCV infection, which can result in liver cirrhosis, hepatic failure or hepatocellular carcinoma. The HCV core protein is a highly basic, RNA-binding protein that forms the viral capsid. The E1 and E2 envelope glycoproteins are necessary for viral entry and fusion. Non-structural proteins include NS2, NS3, NS4A and 4B, and NS5A and 5B. The NS2-NS3 complex functions as a protease, and NS3 also has a helicase/NTPase domain. NS4A is a cofactor of NS3 protease activity. NS3-NS4A protease is one target of anti-HCV drugs. NS4B is a membrane anchor for the replication complex, and NS5A plays a role in regulating viral replication. NS5B is an RNA-dependent RNA polymerase. [NCBI Books: NBK1630] Source: Regenstrief LOINC, NCBI Books: NBK1630

Reference Information

Type Source Reference
Mapping Guidance Regenstrief Help Viral load Mapper’s Guide for the Top 2000 plus LOINC Laboratory Observations

Fully-Specified Name

Component
Hepatitis C virus RNA
Property
NCnc
Time
Pt
System
Ser/Plas
Scale
Qn
Method
Probe.amp.tar

Additional Names

Short Name
HCV RNA # SerPl NAA+probe
Display Name
HCV RNA NAA+probe [#/Vol]
Consumer Name Alpha Get Info
Hepatitis C virus (HCV), Blood

Basic Attributes

Class
MICRO
Type
Laboratory
First Released
Version 1.0m
Last Updated
Version 2.73
Order vs. Observation
Both
Common Test Rank Get Info
3513

Member of these Panels

LOINC Long Common Name
75888-8 HCV RNA screening tests - Meaningful Use set
50023-1 Hepatitis C virus RNA panel (viral load) in Serum or Plasma by NAA with probe detection

Member of these Groups Get Info

LOINC Group Group Name
LG32754-0 Hepatitis C virus

Language Variants Get Info

Tag Language Translation
de-DE German (Germany) Hepatitis-C-Virus RNA:Anzahl pro Volumen:Zeitpunkt:Serum oder Plasma:Quantitativ:Zielfragmentamplifikation mit Sondendetektion
Synonyms: Hepacivirus C; HCV
el-GR Greek (Greece) Ιός Ηπατίτιδας C RNA:Αριθμητική συγκέντρωση:Χρονική στιγμή:Ορός/Πλάσμα:Ποσοτική:Ανιχνευτής με ενίσχυση στόχου
es-AR Spanish (Argentina) ARN del virus de la hepatitis C:concentración de número:punto en el tiempo:suero/plasma:cuantitativo:sonda.amplificación.blanco
es-ES Spanish (Spain) Virus Hepatitis C RNA:Concentración de número:Punto temporal:Suero o Plasma:Qn:Sonda con amplificación dirigida
Synonyms: Cuantitativo
es-MX Spanish (Mexico) ARN del virus de la hepatitis C:Concentración numérica:Punto temporal:Suero o Plasma:Cuantitativo:Amplificación de ácidos nucleicos con detección de sonda
fr-CA French (Canada) Virus de l'hépatite C ARN:Concentration numérique:Temps ponctuel:Sérum/Plasma:Quantitatif:Sonde avec amplification de la cible
fr-FR French (France) Hépatite C virus ARN:Nombre/Volume:Ponctuel:Sérum/Plasma:Numérique:PCR amplification de cible
fr-BE French (Belgium) Virus de l'hépatite C ARN:Concentration numérique:Temps ponctuel:Sérum/Plasma:Quantitatif:Sonde avec amplification de la cible
Synonyms: HCV
it-IT Italian (Italy) Epatite C, virus RNA:NCnc:Pt:Siero/Plasma:Qn:Sonda.amp.tar
Synonyms: Concentrazione Numerica Microbiologia Plasma Punto nel tempo (episodio) Siero Siero o Plasma Sonda con amplificazione Sonda con amplificazione del target Sonda di DNA Virus dell''epatite C
ko-KR Korean (Korea, Republic Of) C형 간염 바이러스 리보핵산:계수/부피:검사시점:혈청/혈장:정량:DNA 탐색자.증폭.표적
nl-NL Dutch (Netherlands) Hepatitis C-virus RNA:aantal/volume:moment:serum of plasma:kwantitatief:probe-detectie
Synonyms: probe.amp.tar
pt-BR Portuguese (Brazil) Hepatite C vírus RNA:NCnc:Pt:Sor/Plas:Qn:Sonda com limite de detecção da amplificação de alvo
Synonyms: Ribonucleic acid; HCV; Hep C; #; Number concentration; Count/mass; Count; AcS; CT; Acsolute; Acsolutes; Cnt; Point in time; Random; SerPl; SerPlas; SerP; Serum; SR; Plasma; Pl; Plsm; Quantitative; QNT; Quant; Quan; PCR; Polymerase chain reaction; Transcription mediated amplification; NASBA; Nucleic acid sequence based analysis; SDA; Strand Displacement Amplification; LAT; Ligation-activated transcription; 3SR SR; 3 Self-Sustaining Sequence Replication; LCR; Ligase chain reaction; QBR; Q-Beta Replicase or probe amplification category method; Probe with target amplification; NAAT; TMA; Amp Prb; Probe with ampification; DNA probe; Amplified; Hepatit; Hepatis; Microbiology; Viral load
ru-RU Russian (Russian Federation) Гепатита С вирус РНК:КолОб:ТчкВрм:Сыв/Плаз:Колич:Проба.усил.миш
Synonyms: ДНК проба;ДНК зонд Количественный Количество в объеме Плазма Проба с мишени усилением Сыворотка Сыворотка или Плазма Точка во времени;Момент
tr-TR Turkish (Turkey) Hepatit C virüsü RNA:SayKons:Zmlı:Ser/Plaz:Kant:Prob.amf.hdf
uk-UA Ukrainian (Ukraine) Вірусу Гепатиту С РНК:Чисельна Концентрація:МоментЧасу:Сироватка/Плазма:Кількісно:Зонд-детекція. цільова аміпліфікація НК
Synonyms: #; 3 Self-Sustaining Sequence Replication; 3SR SR; ABS; absolute; absolutes; Amplif; Amplification; Amplified; Cnt; Count; Count/volume; CT; DNA NUCLEIC ACID PROBE; DNA probe; HCV; Hep; Hep C; Hepatis; Hepatit; Hepatology; ID; Infectious Disease; InfectiousDisease; LAT; LCR; Ligase chain reaction; Ligation-activated transcription; Liver; Microbiology; NAA+probe; NAAT; NASBA; Nucleic acid sequence based analysis; Number concentration; Number Concentration (count/vol); PCR; Pl; Plasma; Plsm; Point in time; Polymerase chain reaction; Probe amp; Probe with ampification; Probe with target amplification; QBR; QNT; Quan; Quant; Quantitative; Random; Ribonucleic acid; SDA; SerP; SerPl; SerPlas; Serum; Serum or plasma; SR; Strand Displacement Amplification; TMA; Transcription mediated amplification; UniversalLabOrders; Viral load
zh-CN Chinese (China) 丙型肝炎病毒 RNA:计数型浓度:时间点:血清/血浆:定量型:探针法.基因扩增.靶向
Synonyms: C 型;丙;丙型 HCV RNA HCV;Hep C;丙型肝炎;丙肝;丙肝病毒;肝炎病毒 C 型 Hep C RNA 丙肝病毒 RNA 传染性肝炎 传染毒;传染毒素;滤过性病原体;病毒类;过滤性病原体 借助扩增的探针方法;借助扩增的探针法;探针法.扩增 借助靶向扩增的探针方法;借助靶向扩增的探针法;探针法.扩增.靶向 单位体积内的数量或计数;数量型浓度(单位体积);数量或计数型浓度(计数/体积);数量或计数型浓度(单位体积);计数型浓度(单位体积) 可用数量表示的;定量性;数值型;数量型;连续数值型标尺 微生物学;微生物学试验;微生物学试验（培养、DNA、抗原及抗体） 扩增型 扩增性 数量型浓度 探针法.基因扩增.靶向 数量型浓度 探针法.扩增.靶向 数量或计数型浓度 探针法.扩增.靶向 时刻;随机;随意;瞬间 核糖核酸;Ribonucleic acid 病毒负荷 病毒负荷量 病毒负载 病毒载量 病毒载量（Viral load） 经过扩增的 肝 肝炎病毒 C 型 RNA 脱氧核糖核酸探针 血清或血浆 计数型浓度 探针法.基因扩增.靶向 计数型浓度 探针法.扩增.靶向

Example Units

Unit Source
Copies/mL REGENSTRIEF
{copies}/mL Example UCUM Units

LOINC Terminology Service (API) using HL7® FHIR® Get Info

CodeSystem lookup
https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=20416-4