20802-5

Epizootic hemorrhagic disease virus neutralizing antibody [Presence] in Serum by Neutralization test

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Part Descriptions

LP18831-5 Epizootic hemorrhagic disease virus
Epizootic Hemorrhagic Disease virus (EHDV) causes an arthropod-bourne illness primarily of white-tailed deer, mule deer and pronghorn antelope (although other species can be affected). It belongs to the genus Orbivirus, family Reoviridae with seven serotypes currently recognized. EHDV is transmitted by Cullicoides midges (tiny biting flies), and causes anorexia, weakness, fever, and edema. It can be fatal within 8-36 hours in naive animals. Although it primarily circulates in the southern United States, the periodic movement of infected vector insects to the northern United States in recent years has resulted in severe outbreaks in northern states (such as NY in 2011). EHDV virus has also been reported in South America, Asia, Africa, Australia, and the Caribbean. The EHD virus is sometimes confused with the related Bluetongue virus and crossreacts with it on many blood testshttps://cwhl.vet.cornell.edu/disease/epizootic-hemorrhagic-disease. Source: Regenstrief LOINC

LP207365-0 Ab.Neut
Neutralizing antibodies are antibodies that interfere with the interaction between the virus and its host cell receptor, therefore preventing infectivity. Neutralizing antibodies can be detected using a traditional VNT or other methods such as pseudovirus VNT and surrogate VNT. VNT and pseudovirus VNT use live virus (the actual virus or a recombinant virus that incorporates the viral antigen of interest, respectively) and cell culture to assess the virus-host interaction and whether neutralizing antibodies are present that block that interaction. Surrogate VNT (sVNT) does not use live virus but rather uses purified viral antigen and host cell receptor protein to mimic the same interaction. The sVNT method is currently (2021) represented in LOINC as IA, because it is an immunoassay-based method. Source: Regenstrief LOINC

LP6416-4 Neut
In LOINC, the Method "Neut" represents the virus neutralization test (VNT), also called conventional VNT, which is a specific laboratory method that is used primarily for identifying whether neutralizing antibodies for the virus of interest are present in the patient sample. The VNT involves incubating patient serum with the virus of interest, and then inoculating onto cell culture. If neutralizing antibodies are present and the virus is neutralized, the cells will not be infected. If neutralizing antibodies are not present, the virus will infect the cells in the cell culture. PMID: 32170698 This method can also be used to identify specific virus serotypes or strains, by performing separate tests in which serum is incubated with each of the specific virus serotypes or strains of interest. PMID: 169804 Source: Regenstrief LOINC

LOINC Names Get Info

Fully-Specified Name: Epizootic hemorrhagic disease virus Ab.Neut:PrThr:Pt:Ser:Ord:Neut
Long Common Name: Epizootic hemorrhagic disease virus neutralizing antibody [Presence] in Serum by Neutralization test
Short Name: EHDV NAb Ser Ql Nt
Display Name: Epizootic hemorrhagic disease virus neut ab Neut test Ql (S)
Consumer Name Alpha Get Info: Epizootic Hemorrhagic Disease virus neutralizing antibody, Blood

Part Model Get Info

Component
Epizootic hemorrhagic disease virus Ab.Neut
LP430385-7
- Analyte
  Epizootic hemorrhagic disease virus Ab.Neut
  LP430385-7
  - Component Numerator
    Epizootic hemorrhagic disease virus Ab.Neut
    LP430385-7
    - Component Numerator Core
      Epizootic hemorrhagic disease virus
      LP18831-5
    - Component Numerator Core Suffix
      Ab.Neut
      LP207365-0
  - Component Denominator
    NULL
    - Component Denominator Core
      NULL
    - Component Denominator Core Suffix
      NULL
- Challenge
  NULL
- Adjustment
  NULL
- Count
  NULL
Property
PrThr
LP217195-9
Time
Pt
LP6960-1
- Time Core
  Pt
  LP6960-1
- Time Modifier
  NULL
System
Ser
LP7567-3
- System Core
  Ser
  LP7567-3
- Super System
  NULL
Scale
Ord
LP7751-3
Method
Neut
LP6416-4

Basic Attributes

Class: MICRO
Type: Laboratory
First Released: Version 1.0m
Last Updated: Version 2.72 (NAM)
Change Reason: Release 2.72: COMPONENT: Updated "Ab" to "Ab.Neut" since this test is detecting neutralizing antibodies.; Previous Releases: The PrThr property is used for LOINC terms whose results are reported using an ordered categorical scale, regardless of whether or not an internal threshold was used to make that determination. This change was approved by the Laboratory LOINC Committee in June 2016.
Order vs. Observation: Both

Language Variants Get Info

Tag	Language	Translation
cs-CZ	Czech (Czechia)	Virus epizootického hemoragického onemocnění Ab.neutralizační:Přítomnost nebo práh:Časový bod:Sérum:Ordinální:Neutralizační test
el-GR	Greek (Greece)	Ιός επιζωοτικής αιμορραγικής νόσου Ab.Neut:PrThr:Pt:Ορός:Ord:Ουδετερόφιλα Synonyms: Ab.Neut MICRO Ord PrThr Pt Αντίσωμα Ιός Ιός επιζωοτικής αιμορραγικής νόσου Ορός Ουδετερόφιλα
es-AR	Spanish (Argentina)	[anticuerpo anti - ] virus de la enfermedad hemorrágica epizoótica [Ac]:concentración arbitraria:punto en el tiempo:suero:ordinal:neutralización
es-ES	Spanish (Spain)	Virus de la enfermedad epizootica hemorrágica Anticuerpos antineutrófilos:PrThr:Punto temporal:Suero:Ord:Prueba de neutralización
es-MX	Spanish (Mexico)	Virus de la enfermedad hemorrágica epizoótica Ab:Presencia o umbral:Punto temporal:Suero:Ordinal:Prueba de neutralización
fr-FR	French (France)	Virus de la fièvre hémorragique épizootique Ac neutralisant:Présence/Seuil:Ponctuel:Sérum:Qualitatif:Neutralisation
fr-CA	French (Canada)	Virus maladie hémorragique épizootique Ac.neut:Présence-Seuil:Temps ponctuel:Sérum:Ordinal:Test de neutralisation
it-IT	Italian (Italy)	Malattia emorragica epizootica, virus Ab.Neut:PrThr:Pt:Siero:Ord:Neut Synonyms: anticorpo Microbiologia Presenza o Soglia Punto nel tempo (episodio) Siero Test di neutralizzazione Virus della malattia emorragica epizootica
ko-KR	Korean (Korea, Republic Of)	가축유행성 출혈성 질환 바이러스 항체:임의농도:검사시점:혈청:순위척도:중화
nl-NL	Dutch (Netherlands)	Epizootic hemorrhagic disease virus As.neutraliserend:aanwezigheid:moment:serum:ordinaal:neutralisatietest Synonyms: antistof; antilichaam
pl-PL	Polish (Poland)	Wirus epizootycznej choroby krwotocznej Ab.Neutralizujące:granica wykrywalności:punkt w czasie:surowica:uporządkowany:test neutralizacji Synonyms: Przeciwciała do wirusa epizootycznej choroby krwotocznej Przeciwciała neutralizuące do wirusa epizootycznej choroby krwotocznej Wirus epizootycznej choroby krwotocznej
pt-BR	Portuguese (Brazil)	Doença Epizootica hemorrágica vírus Ac:ACnc:Pt:Soro:Ord:Teste de neutralização Synonyms: ; EHDV; Orbivirus; Epizootic hemorrhagic disease of deer; Arbovirus; Culicoides; Arbitrary concentration; Point in time; Random; Serum; SR; Ql; Ordinal; QL; Qualitative; Qual; Screen; Nt; NT; Neutralization test; Antibodies; Autoantibody; Antibody; Autoantibodies; Antby; Acy; Anti; Dis; Microbiology
zh-CN	Chinese (China)	流行性出血热病毒抗体.中和:存在情况或阈值:时间点:血清:序数型:中和试验 Synonyms: Ab;自身抗体 EHDV Ab EHDV 抗体 EHDV;库蠓;流行性出血热;流行性出血病;流行性出血病病毒;环状病毒;节肢介体病毒;虫传病毒;虫媒病毒;鹿流行性出血热;鹿流行性出血病中和试验;中和抗体;中和传染毒;传染毒素;滤过性病原体;病毒类;过滤性病原体依次型;分类顺序型;定性的;序数型（或称等级型）;性质上的;有序型;有序性分类应答;有序性分类结果;秩次型;等级型;筛查;顺序型存在情况;存在;存在与否;是否存在;阈值;界值;界限;阀值;临界值;存在情况（存在、存在与否、是否存在）或阈值（界值、界限、阀值、临界值）微生物学;微生物学试验;微生物学试验（培养、DNA、抗原及抗体）时刻;随机;随意;瞬间流行性出血热病毒 Ab 流行性出血病病毒 Ab 流行性出血病病毒抗体疾病症

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LOINC Copyright

Copyright © Regenstrief Institute, Inc. All Rights Reserved. To the extent included herein, the LOINC table and LOINC codes are copyright © Regenstrief Institute, Inc. and the Logical Observation Identifiers Names and Codes (LOINC) Committee. See https://loinc.org/license for the full LOINC copyright and license.