Log In

Part Description

LP19680-5   CCR5 gene
The CCR5 gene (chemokine (C-C motif) receptor 5 (gene/pseudogene)) [HGNC Gene ID:1606] is located on chromosome 3p21.31. This gene encodes a member of the beta chemokine receptor family, which is predicted to be a seven transmembrane protein similar to G protein-coupled receptors. This protein is expressed by T cells and macrophages, and is known to be an important co-receptor for macrophage-tropic virus, including HIV, to enter host cells. Defective alleles of this gene have been associated with the HIV infection resistance. The ligands of this receptor include monocyte chemoattractant protein 2 (MCP-2), macrophage inflammatory protein 1 alpha (MIP-1 alpha), macrophage inflammatory protein 1 beta (MIP-1 beta) and regulated on activation normal T expressed and secreted protein (RANTES). Expression of this gene was also detected in a promyeloblastic cell line, suggesting that this protein may play a role in granulocyte lineage proliferation and differentiation. This gene is located at the chemokine receptor gene cluster region. Two transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008] [NCBI Gene ID:1234] Source: National Center for Biotechnology Information (NCBI) Gene

LOINC Names Get Info

Fully-Specified Name
CCR5 gene mutations:Prid:Pt:Bld:Nom:Targeted gene mutation analysis
Long Common Name
CCR5 gene mutations found [Identifier] in Blood by Targeted gene mutation analysis Nominal
Short Name
CCR5 gene Mut Bld Mut Anl
Display Name
CCR5 gene mutations found Targeted gene mutation analysis Nom (Bld)
Consumer Name Alpha Get Info
CCR5 gene mutations found, Blood

Part Model Get Info

  • Component
    CCR5 gene mutations
    LP451899-1
    • Analyte
      CCR5 gene mutations
      LP451899-1
      • Component Numerator
        CCR5 gene mutations
        LP451899-1
      • Component Denominator
        NULL
         
        • Component Denominator Core
          NULL
           
        • Component Denominator Core Suffix
          NULL
           
    • Challenge
      NULL
       
    • Adjustment
      NULL
       
    • Count
      NULL
       
  • Property
    Prid
    LP6850-4
  • Time
    Pt
    LP6960-1
  • System
    Bld
    LP7057-5
    • System Core
      Bld
      LP7057-5
    • Super System
      NULL
       
  • Scale
    Nom
    LP7750-5
  • Method
    Targeted gene mutation analysis
    LP95475-7

Basic Attributes

Class
MOLPATH.MUT
Type
Laboratory
First Released
Version 1.0m
Last Updated
Version 2.83 (NAM)
Change Reason
Based on LOINC Committee review (June 2016), "targeted" was added to the Component to clarify that this test is looking for a specific set of mutations as described in the LOINC User Guide under the Molecular Genetics section.
Order vs. Observation
Both

Language Variants Get Info

TagLanguageTranslation
cs-CZCzech (Czechia)Gen CCR5 cílená mutační analýza:Přítomnost nebo identita:Časový bod:Krev:Nominální:Molekulární genetika
el-GRGreek (Greece)Γονίδιο CCR5 στοχευμένη ανάλυση μεταλλάξεων:Prid:Pt:Αίμα:Nom:Μοριακή γενετική
Synonyms: MOLPATH MOLPATH.MUT Nom Prid Pt Αίμα Γονίδιο Γονίδιο CCR5 Μοριακή γενετική στοχευμένη ανάλυση μεταλλάξεων
es-ARSpanish (Argentina)análisis de la mutación del gen CCR5:presencia o identidad:punto en el tiempo:sangre:Nominal:genética molecular
es-ESSpanish (Spain)Gen CCR5 Analisis de mutaciones:Presencia o identidad:Punto temporal:Sangre:Nom:Genética molecular
es-MXSpanish (Mexico)Análisis de mutaciones dirigidas al gen CCR5:Presencia o identidad:Punto temporal:Sangre:Nominal:Genética molecular
fr-FRFrench (France)CCR5 gène mutation cible trouvée:Identification:Ponctuel:Sang:Résultat nominal:Biologie moléculaire
it-ITItalian (Italy)CCR5, gene analisi di mutazione mirata:Prid:Pt:Sangue:Nom:Molgen
Synonyms: Gene CCR5 Genetica molecolare Mutazione genica Patologia molecolare Presenza o Identità Punto nel tempo (episodio) Sangue
ko-KRKorean (Korea, Republic Of)CCR5 유전자 돌연변이 분석:존재:검사시점:전혈:명칭결과:분자유전
nl-NLDutch (Netherlands)CCR5-gen doelgerichte mutatie-analyse:identificator:moment:bloed:nominaal:moleculair genetisch onderzoek
Synonyms: CCR5 gen molgen targeted
pl-PLPolish (Poland)CCR5 gen ukierunkowana analiza mutacji:obecność lub identyfikacja:punkt w czasie:krew:skala nominalna:genetyka molekularna
Synonyms: Analiza mutacji genu CCR5 diagnostyka molekularna Gen CCR5 wynik kategorialny
pt-BRPortuguese (Brazil)CCR5 análise de mutação genética:Ident:Pt:SgTotal:Nom:Genética molecular
Synonyms: CKR5; CMKBR5; CC-CKR-5; CCCKR5; CKR-5; Chemokine (C-C motif) receptor 5; Identity or presence; Point in time; Random; Blood; WB; Whole blood; Nominal; PCR; Molecular genetics; Mut Anal; Mutations; MOLPATH.MUTATIONS; MOLPATH.MUTATIONS; Molecular pathology
ru-RURussian (Russian Federation)CCR5 ген исследование на мутацию:ПрИд:ТчкВрм:Кр:Ном:МолГен
Synonyms: Кровь Номинальный;Именной Присутствие или Идентификация Точка во времени;Момент
tr-TRTurkish (Turkey)CCR5 geni Mutasyon analizi:MevcKimlik:Zmlı:Kan:Snf:Molgen
zh-CNChinese (China)CCR5 基因 突变分析:存在与否或特征标识:时间点:全血:名义型:分子遗传学类实验室方法
Synonyms: CCCKR5;CC-CKR-5;CKR5;CKR-5;CMKBR5;趋化因子 (C-C 基元) 受体 5;趋化因子 (C-C 基序) 受体 5;趋化素 (C-C 基元) 受体 5;趋化素 (C-C 基序) 受体 5 分子病理学.基因突变;分子病理学.突变;分子病理学试验.基因突变;分子病理学试验.突变;分子病理学试验类.突变;基因突变;突变 分子病理学;分子病理学试验 分子遗传学;分子遗传学方法;分子遗传学类方法;分子遗传学类检验方法;包括 RFL、PCR 及其他方法在内，用于在分子基础上检测遗传属性的方法的大类;聚合酶链反应;聚合酶链式反应 分类型应答;分类型结果;名义性;名称型;名词型;名词性;标称性;没有自然次序的名义型或分类型应答 基因突变分析 存在;存在与否;特征标识;身份;身份标识 时刻;随机;随意;瞬间 血;血液 遗传基因;遗传因子;吉恩;生物基因

LOINC Terminology Service (API) using HL7® FHIR® Get Info

CodeSystem lookup
https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=21207-6